Search Results - "Los Marek"

Novel trends in application of stem cells in skin wound healing by Kucharzewski, Marek, Rojczyk, Ewa, Wilemska-Kucharzewska, Katarzyna, Wilk, Renata, Hudecki, Jacek, Los, Marek J.

“…The latest findings indicate the huge therapeutic potential of stem cells in regenerative medicine, including the healing of chronic wounds. Main stem cell…”
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Betulin and its derivatives as novel compounds with different pharmacological effects by Amiri, Shayan, Dastghaib, Sanaz, Ahmadi, Mazaher, Mehrbod, Parvaneh, Khadem, Forough, Behrouj, Hamid, Aghanoori, Mohamad-Reza, Machaj, Filip, Ghamsari, Mahdi, Rosik, Jakub, Hudecki, Andrzej, Afkhami, Abbas, Hashemi, Mohammad, Los, Marek J., Mokarram, Pooneh, Madrakian, Tayyebeh, Ghavami, Saeid

“…Betulin (B) and Betulinic acid (BA) are natural pentacyclic lupane-structure triterpenoids which possess a wide range of pharmacological activities. Recent…”
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Cancer stem cell markers in common cancers – therapeutic implications by Klonisch, Thomas, Wiechec, Emilia, Hombach-Klonisch, Sabine, Ande, Sudharsana R, Wesselborg, Sebastian, Schulze-Osthoff, Klaus, Los, Marek

“…Rapid advances in the cancer stem cell (CSC) field have provided cause for optimism for the development of more reliable cancer therapies in the future…”
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Airway mesenchymal cell death by mevalonate cascade inhibition: Integration of autophagy, unfolded protein response and apoptosis focusing on Bcl2 family proteins by Ghavami, Saeid, Sharma, Pawan, Yeganeh, Behzad, Ojo, Oluwaseun O., Jha, Aruni, Mutawe, Mark M., Kashani, Hessam H., Los, Marek J., Klonisch, Thomas, Unruh, Helmut, Halayko, Andrew J.

“…HMG-CoA reductase, the proximal rate-limiting enzyme in the mevalonate pathway, is inhibited by statins. Beyond their cholesterol lowering impact, statins have…”
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Direct Mechanical Stimulation of Stem Cells: A Beating Electromechanically Active Scaffold for Cardiac Tissue Engineering by Gelmi, Amy, Cieslar-Pobuda, Artur, de Muinck, Ebo, Los, Marek, Rafat, Mehrdad, Jager, Edwin W. H.

“…The combination of stem cell therapy with a supportive scaffold is a promising approach to improving cardiac tissue engineering. Stem cell therapy can be used…”
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Switching Akt: from survival signaling to deadly response by Los, Marek, Maddika, Subbareddy, Erb, Bettina, Schulze-Osthoff, Klaus

“…Akt, a protein kinase hyperactivated in many tumors, plays a major role in both cell survival and resistance to tumor therapy. A recent study,1 along with…”
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S100A8/A9 induces autophagy and apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes that involves BNIP3 by Ghavami, Saeid, Eshragi, Mehdi, Ande, Sudharsana R, Chazin, Walter J, Klonisch, Thomas, Halayko, Andrew J, Mcneill, Karol D, Hashemi, Mohammad, Kerkhoff, Claus, Los, Marek

“…The complex formed by two members of the S100 calcium-binding protein family, S100A8/A9, exerts apoptosisinducing activity in various cells of different…”
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Akt-mediated phosphorylation of CDK2 regulates its dual role in cell cycle progression and apoptosis by Maddika, Subbareddy, Ande, Sudharsana Rao, Wiechec, Emilia, Hansen, Lise Lotte, Wesselborg, Sebastian, Los, Marek

“…Here, we show that CDK2, an S-phase cyclin-dependent kinase, is a novel target for Akt during cell cycle progression and apoptosis. Akt phosphorylates CDK2 at…”
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S100A8/A9 at low concentration promotes tumor cell growth via RAGE ligation and MAP kinase-dependent pathway by Ghavami, Saeid, Rashedi, Iran, Dattilo, Brian M., Eshraghi, Mehdi, Chazin, Walter J., Hashemi, Mohammad, Wesselborg, Sebastian, Kerkhoff, Claus, Los, Marek

“…The complex formed by two members of the S100 calcium‐binding protein family, S100A8/A9, exerts apoptosis‐inducing activity against various cells, especially…”
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Nuclear localized Akt enhances breast cancer stem-like cells through counter-regulation of p21Waf1/Cip1 and p27kip1 by Jain, Mayur Vilas, Jangamreddy, Jaganmohan R, Grabarek, Jerzy, Schweizer, Frank, Klonisch, Thomas, Cieślar-Pobuda, Artur, Łos, Marek J

“…Cancer stem-like cells (CSCs) are a rare subpopulation of cancer cells capable of propagating the disease and causing cancer recurrence. In this study, we…”
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Apoptin, a tumor-selective killer by Los, Marek, Panigrahi, Soumya, Rashedi, Iran, Mandal, Sanat, Stetefeld, Joerg, Essmann, Frank, Schulze-Osthoff, Klaus

“…Apoptin, a small protein from chicken anemia virus, has attracted great attention, because it specifically kills tumor cells while leaving normal cells…”
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New, exciting developments in experimental therapies in the early 21st century by Los, Marek

“…The volume is dedicated to novel anticancer strategies. Our aim was to identify and cover novel, emerging anticancer approaches that will form the backbone of…”
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Mevalonate cascade regulation of airway mesenchymal cell autophagy and apoptosis: a dual role for p53 by Ghavami, Saeid, Mutawe, Mark M, Sharma, Pawan, Yeganeh, Behzad, McNeill, Karol D, Klonisch, Thomas, Unruh, Helmut, Kashani, Hessam H, Schaafsma, Dedmer, Los, Marek, Halayko, Andrew J

“…Statins inhibit the proximal steps of cholesterol biosynthesis, and are linked to health benefits in various conditions, including cancer and lung disease. We…”
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Progress in Precision Medicine for Head and Neck Cancer by Vakili, Sanaz, Behrooz, Amir Barzegar, Whichelo, Rachel, Fernandes, Alexandra, Emwas, Abdul-Hamid, Jaremko, Mariusz, Markowski, Jarosław, Los, Marek J, Ghavami, Saeid, Vitorino, Rui

“…This paper presents a comprehensive comparative analysis of biomarkers for head and neck cancer (HNC), a prevalent but molecularly diverse malignancy. We…”
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Obesity: pathophysiology and clinical management by Gurevich-Panigrahi, Tatiana, Panigrahi, Soumya, Wiechec, Emilia, Los, Marek

“…Obesity is an increasingly serious socioeconomic and clinical problem. Between (1/4)-(1/3) of population in the developed countries can be classified as obese…”
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Unscheduled Akt-Triggered Activation of Cyclin-Dependent Kinase 2 as a Key Effector Mechanism of Apoptin's Anticancer Toxicity by Maddika, Subbareddy, Panigrahi, Soumya, Wiechec, Emilia, Wesselborg, Sebastian, Fischer, Ute, Schulze-Osthoff, Klaus, Los, Marek

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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New Visions on Natural Products and Cancer Therapy: Autophagy and Related Regulatory Pathways by Martelli, Alma, Omrani, Marzieh, Zarghooni, Maryam, Citi, Valentina, Brogi, Simone, Calderone, Vincenzo, Sureda, Antoni, Lorzadeh, Shahrokh, da Silva Rosa, Simone C, Grabarek, Beniamin Oscar, Staszkiewicz, Rafał, Los, Marek J, Nabavi, Seyed Fazel, Nabavi, Seyed Mohammad, Mehrbod, Parvaneh, Klionsky, Daniel J, Ghavami, Saeid

“…Macroautophagy (autophagy) has been a highly conserved process throughout evolution and allows cells to degrade aggregated/misfolded proteins, dysfunctional or…”
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Adult stem cells and their trans-differentiation potential—perspectives and therapeutic applications by Hombach-Klonisch, Sabine, Panigrahi, Soumya, Rashedi, Iran, Seifert, Anja, Alberti, Esteban, Pocar, Paola, Kurpisz, Maciej, Schulze-Osthoff, Klaus, Mackiewicz, Andrzej, Los, Marek

“…Stem cells are self-renewing multipotent progenitors with the broadest developmental potential in a given tissue at a given time. Normal stem cells in the…”
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Cell survival, cell death and cell cycle pathways are interconnected: Implications for cancer therapy by Maddika, Subbareddy, Ande, Sudharsana Rao, Panigrahi, Soumya, Paranjothy, Ted, Weglarczyk, Kazimierz, Zuse, Anne, Eshraghi, Mehdi, Manda, Kamala D, Wiechec, Emilia, Los, Marek

“…Abstract The partial cross-utilization of molecules and pathways involved in opposing processes like cell survival, proliferation and cell death, assures that…”
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Targeting the EGFR pathway for cancer therapy by Johnston, James B, Navaratnam, Sri, Pitz, Marshall W, Maniate, Jerry M, Wiechec, Emilia, Baust, Heinrich, Gingerich, Joel, Skliris, Georgios P, Murphy, Leigh C, Los, Marek

“…Clinical studies have shown that HER-2/Neu is over-expressed in up to one-third of patients with a variety of cancers, including B-cell acute lymphoblastic…”
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