Search Results - "Lory, Alex"

Antibody-Mediated Inhibition of the FGFR1c Isoform Induces a Catabolic Lean State in Siberian Hamsters by Samms, Ricardo J., Lewis, Jo E., Lory, Alex, Fowler, Maxine J., Cooper, Scott, Warner, Amy, Emmerson, Paul, Adams, Andrew C., Luckett, Jeni C., Perkins, Alan C., Wilson, Dana, Barrett, Perry, Tsintzas, Kostas, Ebling, Francis J.P.

“…Hypothalamic tanycytes are considered to function as sensors of peripheral metabolism [1]. To facilitate this role, they express a wide range of receptors,…”
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A monoclonal antibody targetting the FGFR‐1c isoform reduces body weight and food intake, which is, associated with a suppression of deiodinase 2 mRNA expression in hypothalamic tanycytes by Samms, Ricardo, Lory, Alex, Roberts, Jessica, Warner, Amy, Sundquis, Sarah, Emmerson, Paul, Perry, Barrett, Tsintzas, Kostas, Ebling, Fran

“…Abstract only FGF21 plays a role in the peripheral regulation of energy balance, but its putative receptor (FGFR1c) is also expressed in tanycyte cells of the…”
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