Search Results - "Lormand, Justin"

Oxidative guanine base damage regulates human telomerase activity by Fouquerel, Elise, Lormand, Justin, Bose, Arindam, Lee, Hui-Ting, Kim, Grace S, Li, Jianfeng, Sobol, Robert W, Freudenthal, Bret D, Myong, Sua, Opresko, Patricia L

“…Opposing effects of 8-oxodGTP on telomerase activity – promoting elongation by destabilizing G4 structures or inhibiting elongation by acting as a chain…”
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Structural characterization of NrnC identifies unifying features of dinucleotidases by Lormand, Justin D, Kim, Soo-Kyoung, Walters-Marrah, George A, Brownfield, Bryce A, Fromme, J Christopher, Winkler, Wade C, Goodson, Jonathan R, Lee, Vincent T, Sondermann, Holger

“…RNA degradation is fundamental for cellular homeostasis. The process is carried out by various classes of endolytic and exolytic enzymes that together degrade…”
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A dedicated diribonucleotidase resolves a key bottleneck for the terminal step of RNA degradation by Kim, Soo-Kyoung, Lormand, Justin D, Weiss, Cordelia A, Eger, Karin A, Turdiev, Husan, Turdiev, Asan, Winkler, Wade C, Sondermann, Holger, Lee, Vincent T

“…Degradation of RNA polymers, an ubiquitous process in all cells, is catalyzed by specific subsets of endo- and exoribonucleases that together recycle RNA…”
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Diribonuclease activity eliminates toxic diribonucleotide accumulation by Kim, Soo-Kyoung, Orr, Mona W., Turdiev, Husan, Jenkins, Conor C., Lormand, Justin D., Myers, Tanner M., Burnim, Audrey Andy, Carter, Jared.A., Kung, Warren C., Jiang, Xiaofang, Sondermann, Holger, Winkler, Wade C., Lee, Vincent T.

“…RNA degradation is a central process required for transcriptional regulation. Eventually, this process degrades diribonucleotides into mononucleotides by…”
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Correction: A dedicated diribonuclease resolves a key bottleneck for the terminal step of RNA degradation by Kim, Soo-Kyoung, Lormand, Justin D, Weiss, Cordelia A, Eger, Karin A, Turdiev, Husan, Turdiev, Asan, Winkler, Wade C, Sondermann, Holger, Lee, Vincent T

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Correction: Structural characterization of NrnC identifies unifying features of dinucleases by Lormand, Justin D, Kim, Soo-Kyoung, Walters-Marrah, George A, Brownfield, Bryce A, Fromme, J Christopher, Winkler, Wade C, Goodson, Jonathan R, Lee, Vincent T, Sondermann, Holger

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Telomeric Overhang Length Determines Structural Dynamics and Accessibility to Telomerase and ALT-Associated Proteins by Hwang, Helen, Kreig, Alex, Calvert, Jacob, Lormand, Justin, Kwon, Yongho, Daley, James M., Sung, Patrick, Opresko, Patricia L., Myong, Sua

“…The G-rich single-stranded DNA at the 3′ end of human telomeres can self-fold into G-quaduplex (GQ). However, telomere lengthening by telomerase or the…”
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DNA polymerase δ stalls on telomeric lagging strand templates independently from G-quadruplex formation by Lormand, Justin D, Buncher, Noah, Murphy, Connor T, Kaur, Parminder, Lee, Marietta Y, Burgers, Peter, Wang, Hong, Kunkel, Thomas A, Opresko, Patricia L

“…Previous evidence indicates that telomeres resemble common fragile sites and present a challenge for DNA replication. The precise impediments to replication…”
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Structural characterization of NrnC identifies unifying features of dinucleases by Lormand, Justin D, Kim, Soo-Kyoung, Walters-Marrah, George A, Brownfield, Bryce A, Fromme, J Christopher, Winkler, Wade C, Goodson, Jonathan R, Lee, Vincent T, Sondermann, Holger

“…RNA degradation is fundamental for cellular homeostasis. The process is carried out by various classes of endolytic and exolytic enzymes that together degrade…”
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A dedicated diribonuclease resolves a key bottleneck for the terminal step of RNA degradation by Kim, Soo-Kyoung, Lormand, Justin D, Weiss, Cordelia A, Eger, Karin A, Turdiev, Husan, Turdiev, Asan, Winkler, Wade C, Sondermann, Holger, Lee, Vincent T

“…Degradation of RNA polymers, an ubiquitous process in all cells, is catalyzed by specific subsets of endo- and exoribonucleases that together recycle RNA…”
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Unifying the Features that Determine Substrate Preferences of NanoRNases by Lormand, Justin David

“…RNA polymers are synthesized, degraded, and modified through several varied cellular processes. The ability of cells to degrade and recycle their RNA products…”
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