Search Results - "Lorizio, Wendy"
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Clinical and biomarker predictors of side effects from tamoxifen
Published in Breast cancer research and treatment (01-04-2012)“…Tamoxifen decreases breast cancer recurrence, mortality, and breast cancer risk in high-risk women. Despite these proven benefits, tamoxifen use is often…”
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Multi-omics in nasal epithelium reveals three axes of dysregulation for asthma risk in the African Diaspora populations
Published in Nature communications (28-05-2024)“…Asthma has striking disparities across ancestral groups, but the molecular underpinning of these differences is poorly understood and minimally studied. A goal…”
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Pharmacogenetic testing affects choice of therapy among women considering tamoxifen treatment
Published in Genome medicine (04-10-2011)“…Pharmacogenetic testing holds major promise in allowing physicians to tailor therapy to patients based on genotype. However, there is little data on the impact…”
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4
Estimation of tamoxifen metabolite concentrations in the blood of breast cancer patients through CYP2D6 genotype activity score
Published in Breast cancer research and treatment (01-06-2012)“…Tamoxifen, a prodrug used for adjuvant breast cancer therapy, requires conversion to the active metabolite endoxifen through CYP 2D6. We aimed to construct an…”
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Genetic Ancestry and Risk Factors for Breast Cancer among Latinas in the San Francisco Bay Area
Published in Cancer epidemiology, biomarkers & prevention (01-10-2006)“…Background: Genetic association studies using case-control designs are susceptible to false-positive and false-negative results if there are differences in…”
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Principal stratification analysis to determine health benefit of indoor air pollution reduction in a randomized environmental intervention in COPD: Results from the CLEAN AIR study
Published in The Science of the total environment (10-04-2023)“…Indoor air quality represents a modifiable exposure to Chronic Obstructive Pulmonary Disease (COPD) health. In a randomized controlled trial (CLEAN AIR study),…”
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Prevalence of BRCA Mutations Among Women with Triple-Negative Breast Cancer (TNBC) in a Genetic Counseling Cohort
Published in Annals of surgical oncology (01-10-2013)“…Background Revised NCCN guidelines recommend that women ≤60 years with triple-negative breast cancer (TNBC) be referred for consideration of genetic…”
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A cross sectional pilot study to assess the role of phthalates on respiratory morbidity among patients with chronic obstructive pulmonary disease
Published in Environmental research (15-05-2023)“…Chronic Obstructive Pulmonary Disease (COPD) affects ∼16 million U.S. adults. Phthalates, synthetic chemicals in consumer products, may adversely impact…”
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Indoor Pollution and Lung Function Decline in Current and Former Smokers: SPIROMICS AIR
Published in American journal of respiratory and critical care medicine (15-11-2023)“…Indoor pollutants have been associated with chronic obstructive pulmonary disease morbidity, but it is unclear whether they contribute to disease progression…”
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Patterns and Predictors of Air Cleaner Adherence Among Adults with COPD
Published in Chronic obstructive pulmonary diseases (29-07-2022)“…Poor indoor air quality has been associated with worse chronic obstructive pulmonary disease (COPD) morbidity. In-home portable air cleaners reduce indoor…”
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Higher Plasma Omega-3 Levels are Associated With Improved Exacerbation Risk and Respiratory-Specific Quality of Life in COPD
Published in Chronic obstructive pulmonary diseases (29-05-2024)“…Omega-3 polyunsaturated fatty acids (PUFAs) have been associated with systemic anti-inflammatory responses. Dietary intake of omega-3 PUFAs eicosapentaenoic…”
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Food Insecurity is Associated With COPD Morbidity and Perceived Stress
Published in Chronic obstructive pulmonary diseases (01-01-2024)“…Low socioeconomic status (SES) has been associated with worse clinical outcomes in chronic obstructive pulmonary disease (COPD). Food insecurity is more common…”
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