Search Results - "Lorini, Luigi"

Human Papilloma Virus (HPV) driven oropharyngeal cancer in current or previous heavy smokers: should we look for a different treatment paradigm? by Lorini, Luigi, Bossi, Paolo, Psyrri, Amanda, Bonomo, Pierluigi

“…Human papillomavirus Virus (HPV)-associated oropharyngeal squamous cell carcinoma (OSCC) has increased in incidence in recent decades and represents a…”
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Prognosis and management of recurrent and/or metastatic head and neck adenoid cystic carcinoma by Lorini, Luigi, Ardighieri, Laura, Bozzola, Anna, Romani, Chiara, Bignotti, Eliana, Buglione, Michela, Guerini, Andrea, Lombardi, Davide, Deganello, Alberto, Tomasoni, Michele, Bonini, Sara Anna, Sigala, Sandra, Farina, Davide, Ravanelli, Marco, Bossi, Paolo

“…•Adenoid cystic carcinoma is a rare tumor with a long-term prognosis.•Lack of clinical data about prognostic factors in recurrent/metastatic disease.•Clinical…”
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Diving into hot topics of salivary gland carcinoma management—an EORTC young and early career investigator survey by Lorini, Luigi, Ronchi, Sara, Nevens, Daan, Klinghammer, Konrad, Orlandi, Ester, Bossi, Paolo, Szturz, Petr

“…Introduction Recently, the ASCO and ESMO guidelines on salivary gland carcinomas (SGCs) have been released. However, several crucial points lack strong…”
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Advanced Cutaneous Squamous Cell Carcinoma Management in Immunotherapy Era: Achievements and New Challenges by Lorini, Luigi, Alberti, Andrea, Bossi, Paolo

“…Introduction of immunotherapy (IT) has radically changed the therapeutic scenario in patients affected by locally advanced and/or metastatic cutaneous squamous…”
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Treatment of Cutaneous Squamous Cell Carcinoma with Immune Checkpoint Inhibitors in Special Populations by Bossi, Paolo, Lorini, Luigi

“…Cutaneous squamous cell carcinoma (cSCC) may develop in patients with dysregulated immune activation (pre-existing autoimmune diseases or immunosuppression due…”
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Functional profiles of curatively treated adenoid cystic carcinoma unveil prognostic features and potentially targetable pathways by Romani, Chiara, Lorini, Luigi, Bozzola, Anna, Bignotti, Eliana, Tomasoni, Michele, Ardighieri, Laura, Bugatti, Mattia, Battocchio, Simonetta, Ravaggi, Antonella, Tomasini, Davide, Ravanelli, Marco, Gurizzan, Cristina, Lombardi, Davide, Mattavelli, Davide, Calza, Stefano, Piazza, Cesare, Bossi, Paolo

“…Adenoid cystic carcinoma (ACC) of salivary gland is a slowly growing tumor showing a propensity for delayed recurrence, with decreased survival rates. The…”
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Cytotoxic effects of targeted agent alone or with chemotherapy in the treatment of adenoid cystic carcinoma: a preclinical study by Savarese, Teresa, Abate, Andrea, Basnet, Ram Manohar, Lorini, Luigi, Gurizzan, Cristina, Tomasoni, Michele, Lombardi, Davide, Tomasini, Davide, Zizioli, Daniela, Memo, Maurizio, Berruti, Alfredo, Bonini, Sara A., Sigala, Sandra, Bossi, Paolo

“…Adenoid cystic carcinoma (ACC) is a rare malignancy characterized by high incidence of relapse. When relapsing, ACC has an indolent but relentless behaviour,…”
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The association of cemiplimab plus sonidegib for synchronous cutaneous squamous cell carcinoma and basal cell carcinoma of the head and neck: Two case reports by Colombo, Elena, Gurizzan, Cristina, Ottini, Arianna, Caspani, Francesca, Bergamini, Cristiana, Locati, Laura D, Marchiselli, Chiara, Alberti, Andrea, Lorini, Luigi, Licitra, Lisa F, Bossi, Paolo, Resteghini, Carlo

“…Basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (cSCC) are the most frequent cancers in humans, with cumulative ultraviolet radiation…”
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Immunotherapy in elderly head and neck cancer patients: a systematic review and meta-analysis by Salvestrini, Viola, Caini, Saverio, Scricciolo, Melissa, Saerens, Michael, Bollen, Heleen, Bonomo, Pierluigi, Caparrotti, Francesca, Lorini, Luigi, Oliva, Marc, Urbanowicz-Nijaki, Maria, Szturz, Petr

“…Over the past years, there has been a growing interest in the role of immunotherapy in locally advanced (LA) and recurrent and metastatic head and neck…”
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Immunotherapy for the prevention of high-risk oral disorders malignant transformation: the IMPEDE trial by Gurizzan, Cristina, Lorini, Luigi, Paderno, Alberto, Tomasoni, Michele, Zigliani, Gabriele, Bozzola, Anna, Ardighieri, Laura, Battocchio, Simonetta, Bignotti, Eliana, Ravaggi, Antonella, Romani, Chiara, De Cecco, Loris, Serafini, Mara Serena, Miceli, Rosalba, Bardellini, Elena, Majorana, Alessandra, Piazza, Cesare, Bossi, Paolo

“…Oral Potentially Malignant Disorders (OPMD) have a non-negligible malignant transformation rate of up to 8%. Loss of heterozygosity (LOH) in critical…”
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Treatment Stratification in First-Line Recurrent or Metastatic Head and Neck Cancer, on Behalf of the EORTC Young Investigator Head and Neck Cancer Group by Klinghammer, Konrad, Lorini, Luigi, Nevens, Daan, Simon, Christian, Machiels, Jean-Pascal, Bossi, Paolo

“…Multiple factors differentially influence treatment decisions in the first line treatment of recurrent/metastatic HNSCC. The EORTC Young investigator group…”
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Biomarkers in head and neck squamous cell carcinoma: unraveling the path to precision immunotherapy by Saini, Kamal S, Somara, Sasikala, Ko, Heidi C, Thatai, Purva, Quintana, Angela, Wallen, Zachary D, Green, Michelle F, Mehrotra, Ravi, McGuigan, Sandra, Pang, Lingjuan, Das, Soma, Yadav, Kavita, Neric, Dobrica, Cantini, Luca, Joshi, Chinmayee, Iwamoto, Kazuya, Dubbewar, Sudha, Vidal, Laura, Chico, Isagani, Severson, Eric, Lorini, Luigi, Badve, Sunil, Bossi, Paolo

“…Recent strides in understanding the molecular underpinnings of head and neck cancers have sparked considerable interest in identifying precise biomarkers that…”
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Is precision medicine the solution to improve organ preservation in laryngeal/hypopharyngeal cancer? A position paper by the Preserve Research Group by Mattavelli, Davide, Wichmann, Gunnar, Smussi, Davide, Paderno, Alberto, Plana, Maria Serrahima, Mesia, Ricard Nin, Compagnoni, Micaela, Medda, Alessandro, Chiocca, Susanna, Calza, Stefano, Zhan, Yinxiu, Rognoni, Carla, Tarricone, Rosanna, Stucchi, Erika, Lorini, Luigi, Gurizzan, Cristina, Khelik, Ksenia, Hovig, Eivind, Dietz, Andreas, Piazza, Cesare, Bossi, Paolo

“…In locally advanced (LA) laryngeal/hypopharyngeal squamous cell carcinoma (LHSCC), larynx preservation (LP) strategies aim at the cure of the disease while…”
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Not all hematopoietic growth factors are created equal: should we gain information for their use with immunotherapy? by Bossi, Paolo, Gurizzan, Cristina, Lorini, Luigi, di Mauro, Pierluigi, Sardini, Chiara, Merlano, Marco

“…Myeloid growth factors, either granulocyte colony-stimulating factor (CSF) or granulocyte-macrophage CSF, are widely used to reduce the incidence and severity…”
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Molecular Basis and Rationale for the Use of Targeted Agents and Immunotherapy in Sinonasal Cancers by Esposito, Andrea, Stucchi, Erika, Baronchelli, Maria, Di Mauro, Pierluigi, Ferrari, Marco, Lorini, Luigi, Gurizzan, Cristina, London, Nyall Robert Jr, Hermsen, Mario, Lechner, Matt, Bossi, Paolo

“…Despite the progress of surgery, radiotherapy, and neoadjuvant chemotherapy, the prognosis for advanced sinonasal cancers (SNCs) remains poor. In the era of…”
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New Challenges in Evaluating Outcomes after Immunotherapy in Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma by Alberti, Andrea, Lorini, Luigi, Ravanelli, Marco, Perri, Francesco, Vinches, Marie, Rondi, Paolo, Romani, Chiara, Bossi, Paolo

“…In many recurrent and/or metastatic cancers, the advent of immunotherapy opens up new scenarios of treatment response, with new phenomena, such as…”
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Clinical and Histological Prognostic Factors of Recurrence and Malignant Transformation in a Large Series of Oral Potentially Malignant Disorders by Lorini, Luigi, Tomasoni, Michele, Gurizzan, Cristina, Magri, Chiara, Facchetti, Mattia, Battocchio, Simonetta, Romani, Chiara, Ravanelli, Marco, Oberti, Arianna, Bozzola, Anna, Bardellini, Elena, Paderno, Alberto, Mattavelli, Davide, Lombardi, Davide, Grammatica, Alberto, Deganello, Alberto, Facchetti, Fabio, Calza, Stefano, Majorana, Alessandra, Piazza, Cesare, Bossi, Paolo

“…Oral potentially malignant disorders (OPMDs) represent a heterogeneous set of different histological lesions, characterized by the capacity to transform in…”
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Accurate Triage of Oncological Patients for Safely Continuing Cancer Therapy During the SARS-CoV-2 Pandemic by Gurizzan, Cristina, Pedersini, Rebecca, Fornaro, Carla, Sardini, Chiara, Zamparini, Manuel, Monteverdi, Sara, Tovazzi, Valeria, Cosentini, Deborah, Dalla Volta, Alberto, Baggi, Alice, Turla, Antonella, Di Mauro, Pierluigi, Lorini, Luigi, Laganà, Marta, Bianchi, Susanna, Grisanti, Salvatore, Consoli, Francesca, Conti, Elisabetta, Bossi, Paolo, Berruti, Alfredo

“…To evaluate the efficacy of clinical triage of oncological patients for safe continuation of cancer therapy implemented during the first SARS-CoV-2 outbreak…”
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Oral potentially malignant disorders: new insights for future treatment by Gurizzan, Crisitna, Lorini, Luigi, Bossi, Paolo

“…The purpose of this review is to define the issues regarding oral potentially malignant disorders (OPMDs) and provide an overview of currently available…”
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The predictive role of PD-L1 in head and neck cancer: A systematic review and meta-analysis by Paderno, Alberto, Petrelli, Fausto, Lorini, Luigi, Capriotti, Vincenzo, Gurizzan, Cristina, Bossi, Paolo

“…•PD-L1 expression in HNSCC patients is significantly correlated with improved overall survival when treated with PD-1 or PD-L1 inhibitors.•Patients with higher…”
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