Search Results - "Lorieau, L."
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complete influenza hemagglutinin fusion domain adopts a tight helical hairpin arrangement at the lipid:water interface
Published in Proceedings of the National Academy of Sciences - PNAS (22-06-2010)“…All but five of the N-terminal 23 residues of the HA2 domain of the influenza virus glycoprotein hemagglutinin (HA) are strictly conserved across all 16…”
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pH-triggered, activated-state conformations of the influenza hemagglutinin fusion peptide revealed by NMR
Published in Proceedings of the National Academy of Sciences - PNAS (04-12-2012)“…The highly conserved first 23 residues of the influenza hemagglutinin HA2 subunit constitute the fusion domain, which plays a pivotal role in fusing viral and…”
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Conformational dynamics of an intact virus: Order parameters for the coat protein of Pf1 bacteriophage
Published in Proceedings of the National Academy of Sciences - PNAS (29-07-2008)“…This study has examined the atomic-level dynamics of the protein in the capsid of filamentous phage Pf1. This capsid consists of [almost equal to]7,300 small…”
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4
Bolus quality and food comfortability of model cheeses for the elderly as influenced by their texture
Published in Food research international (01-09-2018)“…The aim of this study was to examine the influence of the texture of dairy products on bolus properties and food comfortability as perceived by elderly…”
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Use of Isotropically Tumbling Bicelles to Measure Curvature Induced by Membrane Components
Published in Langmuir (07-10-2014)“…Isotropically tumbling discoidal bicelles are a useful biophysical tool for the study of lipids and proteins by NMR, dynamic light scattering, and small-angle…”
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Relationship among oral health status, bolus formation and food comfortability during consumption of model cheeses in elderly
Published in Food & function (21-08-2021)“…The aim of this study was to investigate the impact of oral impairment on chewing behaviour, food bolus properties and food comfortability during elderly…”
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Partial alignment, residual dipolar couplings and molecular symmetry in solution NMR
Published in Journal of biomolecular NMR (01-09-2019)“…Residual dipolar couplings (RDCs) and residual anisotropic chemical shifts (RACSs) are produced by the partial alignment of solution NMR samples. RDCs and…”
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Mollib: a molecular and NMR data analysis software
Published in Journal of biomolecular NMR (01-10-2017)“…Mollib is a software framework for the analysis of molecular structures, properties and data with an emphasis on data collected by NMR. It uses an open source…”
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Pro‐islet amyloid polypeptide in micelles contains a helical prohormone segment
Published in The FEBS journal (01-10-2020)“…Pro‐islet amyloid polypeptide (proIAPP) is the prohormone precursor molecule to IAPP, also known as amylin. IAPP is a calcitonin family peptide hormone that is…”
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The Influenza Hemagglutinin Fusion Domain Is an Amphipathic Helical Hairpin That Functions by Inducing Membrane Curvature
Published in The Journal of biological chemistry (02-01-2015)“…The highly conserved N-terminal 23 residues of the hemagglutinin glycoprotein, known as the fusion peptide domain (HAfp23), is vital to the membrane fusion and…”
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Structure and Dynamics of Membrane Proteins and Membrane Associated Proteins with Native Bicelles from Eukaryotic Tissues
Published in Biochemistry (Easton) (10-10-2017)“…In vitro studies of protein structure, function, and dynamics typically preclude the complex range of molecular interactions found in living tissues. In vivo…”
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Hybrid NMR: A Union of Solution- and Solid-State NMR
Published in Journal of the American Chemical Society (05-04-2017)“…Hybrid NMR (hdNMR) is a powerful new tool that combines the strengths of solution- and solid-state NMR to measure dipolar, chemical shift, and quadrupolar…”
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Conformational Flexibility of a Microcrystalline Globular Protein: Order Parameters by Solid-State NMR Spectroscopy
Published in Journal of the American Chemical Society (06-09-2006)“…The majority of protein structures are determined in the crystalline state, yet few methods exist for the characterization of dynamics for crystalline…”
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Super resolution NOESY spectra of proteins
Published in Journal of biomolecular NMR (01-04-2019)“…Spectral resolution remains one of the most significant limitations in the NMR study of biomolecules. We present the srNOESY (super resolution nuclear…”
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Membrane Fusion and Infection of the Influenza Hemagglutinin
Published in Advances in experimental medicine and biology (2017)“…The influenza virus is a major health concern associated with an estimated 5000 to 30,000 deaths every year (Reed et al. 2015) and a significant economic…”
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Helical Hairpin Structure of Influenza Hemagglutinin Fusion Peptide Stabilized by Charge−Dipole Interactions between the N-Terminal Amino Group and the Second Helix
Published in Journal of the American Chemical Society (09-03-2011)“…The fusion domain of the influenza coat protein hemagglutinin HA2, bound to dodecyl phosphocholine micelles, was recently shown to adopt a structure consisting…”
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The impact of influenza hemagglutinin fusion peptide length and viral subtype on its structure and dynamics
Published in Biopolymers (01-03-2013)“…A peptide comprising no fewer than the first 20 residues of the influenza hemagglutinin HA2 subunit suffices to induce lipid mixing between the membranes of…”
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A Positively Charged Liquid Crystalline Medium for Measuring Residual Dipolar Couplings in Membrane Proteins by NMR
Published in Journal of the American Chemical Society (23-09-2015)“…Residual Dipolar Couplings (RDCs) are integral to the refinement of membrane protein structures by NMR since they accurately define the orientation of helices…”
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Impact of the dairy product structure and protein nature on the proteolysis and amino acid bioaccessiblity during in vitro digestion
Published in Food hydrocolloids (01-09-2018)“…Elderly people exhibit specific nutritional needs, in particular they require higher protein intake. The objective of this study was to compare, using an…”
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Modulating alignment of membrane proteins in liquid-crystalline and oriented gel media by changing the size and charge of phospholipid bicelles
Published in Journal of biomolecular NMR (01-04-2013)“…We demonstrate that alignment of a structured peptide or small protein solubilized in mixed phospholipid:detergent micelles or bicelles, when embedded in a…”
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