Search Results - "Loretz, B."

Nanoparticles made from novel starch derivatives for transdermal drug delivery by Santander-Ortega, M.J., Stauner, T., Loretz, B., Ortega-Vinuesa, J.L., Bastos-González, D., Wenz, G., Schaefer, U.F., Lehr, C.M.

“…The goal of this paper was aimed to the formulation of nanoparticles by using two different propyl-starch derivatives – referred to as PS-1 and PS-1.45 – with…”
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Cyclodextrin-based star polymers as a versatile platform for nanochemotherapeutics: Enhanced entrapment and uptake of idarubicin by Nafee, N., Hirosue, M., Loretz, B., Wenz, G., Lehr, C.-M.

“…•Cyclodextrin-based star polymers containing MMA and tBA as hydrophobic arms.•Star polymers were used to prepare idarubicin-loaded nanoparticles.•Nanoparticles…”
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Telomerase as an emerging target to fight cancer — Opportunities and challenges for nanomedicine by Philippi, C., Loretz, B., Schaefer, U.F., Lehr, C.M.

“…Telomerase as an enzyme is responsible for the renewal of the chromosomal ends, the so-called telomeres. By preventing them from shortening with each cell…”
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Correlation of in vitro and in vivo models for the oral absorption of peptide drugs by Föger, F, Kopf, A, Loretz, B, Albrecht, K, Bernkop-Schnürch, A

“…The aim of this study was to evaluate two in vitro models, Caco-2 monolayer and rat intestinal mucosa, regarding their linear correlation with in vivo…”
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Pulmonary delivery and tissue distribution of aerosolized antisense 2′-O-Methyl RNA containing nanoplexes in the isolated perfused and ventilated rat lung by Dong, M., Mürdter, T.E., Philippi, C., Loretz, B., Schaefer, U.F., Lehr, C.-M., Schwab, M., Ammon-Treiber, S.

“…Lung physiology and tissue distribution of 2′-O-Methyl RNA after administration of aerosolized nanoplexes in the isolated perfused and ventilated rat lung…”
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Inhibition of malarial topoisomerase II in Plasmodium falciparum by antisense nanoparticles by Föger, Florian, Noonpakdee, Wilai, Loretz, Brigitta, Joojuntr, Songwut, Salvenmoser, Willi, Thaler, Marlene, Bernkop-Schnürch, Andreas

“…New effective antimalarial agents are urgently needed due to increasing drug resistance of Plasmodium falciparum. Phosphorothioate antisense…”
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1224 POSTER Docetaxel Delivery Mediated by Nanoparticles of Novel Hydrophobic Starch by Dandekar, P, Jain, R, Stauner, T, Loretz, B, Koch, M, Wenz, G, Lehr, C.M

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1223 POSTER Enhanced Cellular Delivery of Idarubicin by Surface Modification of Propyl Starch Nanoparticles Employing Pteroic Acid Conjugated Polyvinyl Alcohol by Ratnesh, J, Dandekar, P, Loretz, B, Melero, A, Stauner, T, Wenz, G, Koch, M, Lehr, C.M

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Postmenopausal lichen planopilaris also known as fibrosing frontotemporal alopecia Kossard : An evidence-oriented practical guide to treatment from the University of the Saarland, Hair Research Center of the Dr. Rolf M. Schwiete Foundation by Vogt, T, Thomas, C, Reichrath, J, Schilling, L, Mawlood, D, Christmann, R, Loretz, B, Schäfer, U, Lehr, C-M, Müller, C

“…Postmenopausal lichen planopilaris (PLPP), also known as fibrosing frontotemporal alopecia Kossard (FFAK), is a not uncommon inflammatory scalp disease…”
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In vitro models for predictive immunological testing of nanopharmaceuticals targeted to human epithelial barriers by Lehr, C.-M., Hittinger, M., Loretz, B., Murgia, X., Carvalho-Wodarz, C., Schneider-Daum, N.

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Biodynamer Nano-Complexes and -Emulsions for Peptide and Protein Drug Delivery by Liu, Yun, Hamm, Timo, Eichinger, Thomas Ralf, Kamm, Walter, Wieland, Heike Andrea, Loretz, Brigitta, Hirsch, Anna K H, Lee, Sangeun, Lehr, Claus-Michael

“…Therapeutic proteins and peptides offer great advantages compared to traditional synthetic molecular drugs. However, stable protein loading and precise control…”
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Pulmonary delivery and tissue distribution of aerosolized antisense 2'-O-Methyl RNA containing nanoplexes in the isolated perfused and ventilated rat lung by DONG, M, MÜRDTERA, T. E, PHILIPPI, C, LORETZ, B, SCHAEFER, U. F, LEHR, C.-M, SCHWAB, M, AMMON-TREIBERA, S

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Macromolecular Bioscience: A Hydrophobic Starch Polymer for Nanoparticle-Mediated Delivery of Docetaxel by Dandekar, P, Jain, R, Stauner, T, Loretz, B, Koch, M, Wenz, G, Lehr, C.-M

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Oral gene delivery: Strategies to improve stability of pDNA towards intestinal digestion by Loretz, Brigitta, Föger, Florian, Werle, Martin, Bernkop-schnürch, Andreas

“…Purpose: Gastrointestinal (GI) nucleases are responsible for a rapid presystemic degradation of orally administered transgenes. Within the current study, the…”
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Design and evaluation of a chitosan-aprotinin conjugate for the peroral delivery of therapeutic peptides and proteins susceptible to enzymatic degradation by Werle, Martin, Loretz, Brigitta, Entstrasser, Daniel, Föger, Florian

“…One main barrier for the peroral administration of therapeutic peptides and proteins is the enzymatic barrier, that is mediated by luminally secreted and…”
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Enhanced transport of P-glycoprotein substrate saquinavir in presence of thiolated chitosan by Föger, Florian, Kafedjiiski, Krum, Hoyer, Herbert, Loretz, Brigitta, Bernkop-Schnürch, Andreas

“…It was the aim of this study to investigate the effect of chitosan-4-thiobutylamidine (Ch-TBA) and reduced glutathione (GSH) on the absorption of…”
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Postmenopausaler Lichen planopilaris alias fibrosierende frontotemporale Alopezie Kossard: Ein evidenzorientierter „practical guide to treatment“ des Haarforschungszentrums der Dr. Rolf M. Schwiete Stiftung an der Universität des Saarlandes by Vogt, T., Thomas, C., Reichrath, J., Schilling, L., Mawlood, D., Christmann, R., Loretz, B., Schäfer, U., Lehr, C.-M., Müller, C.

“…Zusammenfassung Der postmenopausale Lichen planopilaris (PLPP) alias fibrosierende frontotemporale Alopezie Kossard (FFAK) ist eine nicht seltene entzündliche…”
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