Search Results - "Loret, Erwann P"

Ulva lactuca , A Source of Troubles and Potential Riches by Dominguez, Herminia, Loret, Erwann P

“…is a green macro alga involved in devastating green tides observed worldwide. These green tides or blooms are a consequence of human activities. blooms occur…”
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Didehydro-Cortistatin A Inhibits HIV-1 by Specifically Binding to the Unstructured Basic Region of Tat by Mediouni, Sonia, Chinthalapudi, Krishna, Ekka, Mary K, Usui, Ippei, Jablonski, Joseph A, Clementz, Mark A, Mousseau, Guillaume, Nowak, Jason, Macherla, Venkat R, Beverage, Jacob N, Esquenazi, Eduardo, Baran, Phil, de Vera, Ian Mitchelle S, Kojetin, Douglas, Loret, Erwann P, Nettles, Kendall, Maiti, Souvik, Izard, Tina, Valente, Susana T

“…The intrinsically disordered HIV-1 Tat protein binds the viral RNA transactivation response structure (TAR), which recruits transcriptional cofactors,…”
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What does the structure-function relationship of the HIV-1 Tat protein teach us about developing an AIDS vaccine? by Campbell, Grant R, Loret, Erwann P

“…The human immunodeficiency virus type 1 (HIV-1) trans-activator of transcription protein Tat is an important factor in viral pathogenesis. In addition to its…”
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A Low Molecular Weight Protein from the Sea Anemone Anemonia viridis with an Anti-Angiogenic Activity by Loret, Erwann P, Luis, José, Nuccio, Christopher, Villard, Claude, Mansuelle, Pascal, Lebrun, Régine, Villard, Pierre Henri

“…Sea anemones are a remarkable source of active principles due to a decentralized venom system. New blood vessel growth or angiogenesis is a very promising…”
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HIV-1 Clade B Tat, but Not Clade C Tat, Increases X4 HIV-1 Entry into Resting but Not Activated CD4+ T Cells by Campbell, Grant R., Loret, Erwann P., Spector, Stephen A.

“…CXCR4-using human immunodeficiency virus, type 1 (HIV-1) variants emerge late in the course of infection in >40% of individuals infected with clade B HIV-1 but…”
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Human Immunodeficiency Virus Type 1 Subtype C Tat Fails To Induce Intracellular Calcium Flux and Induces Reduced Tumor Necrosis Factor Production from Monocytes by CAMPBELL, Grant R, WATKINS, Jennifer D, SINGH, Kumud K, LORET, Erwann P, SPECTOR, Stephen A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The Glutamine-rich Region of the HIV-1 Tat Protein Is Involved in T-cell Apoptosis by Campbell, Grant R, Pasquier, Eddy, Watkins, Jennifer, Bourgarel-Rey, Veronique, Peyrot, Vincent, Esquieu, Didier, Barbier, Pascale, de Mareuil, Jean, Braguer, Diane, Kaleebu, Pontiano, Yirrell, David L, Loret, Erwann P

“…Human immunodeficiency virus (HIV) infection and the progression to AIDS are characterized by the depletion of CD4 + T-cells. HIV-1 infection leads to…”
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The C Terminus of HIV-1 Tat Modulates the Extent of CD178-mediated Apoptosis of T Cells by Campbell, Grant R., Watkins, Jennifer D., Esquieu, Didier, Pasquier, Eddy, Loret, Erwann P., Spector, Stephen A.

“…HIV infection and the progression to AIDS are characterized by the depletion of CD4+ T cells through apoptosis of the uninfected bystander cells and the direct…”
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HIV-1 Tat protein enhances microtubule polymerization by de Mareuil, Jean, Carre, Manon, Barbier, Pascale, Campbell, Grant R, Lancelot, Sophie, Opi, Sandrine, Esquieu, Didier, Watkins, Jennifer D, Prevot, Charles, Braguer, Diane, Peyrot, Vincent, Loret, Erwann P

“…HIV infection and progression to AIDS is characterized by the depletion of T cells, which could be due, in part, to apoptosis mediated by the extra-cellular…”
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Identification of a Highly Conserved Surface on Tat Variants by Mediouni, Sonia, Darque, Albert, Ravaux, Isabelle, Baillat, Gilbert, Devaux, Christian, Loret, Erwann P.

“…Extracellular Tat is suspected to protect HIV-1-infected cells from cellular immunity. Seropositive patients are unable to produce neutralizing antibodies…”
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Tat HIV-1 Primary and Tertiary Structures Critical to Immune Response Against Non-homologous Variants by Opi, Sandrine, Péloponèse, Jean-Marie, Esquieu, Didier, Campbell, Grant, de Mareuil, Jean, Walburger, Anne, Solomiac, Murielle, Grégoire, Catherine, Bouveret, Emmanuelle, Yirrell, David L., Loret, Erwann P.

“…Clinical studies show that in the absence of anti-retroviral therapy an immune response against the human immunodeficiency virus type 1 (HIV-1), transacting…”
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Homonuclear 1H NMR and circular dichroism study of the HIV-1 Tat Eli variant by Watkins, Jennifer D, Campbell, Grant R, Halimi, Hubert, Loret, Erwann P

“…The HIV-1 Tat protein is a promising target to develop AIDS therapies, particularly vaccines, due to its extracellular role that protects HIV-1-infected cells…”
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Intradermal injection of a Tat Oyi-based therapeutic HIV vaccine reduces of 1.5 log copies/mL the HIV RNA rebound median and no HIV DNA rebound following cART interruption in a phase I/II randomized controlled clinical trial by Loret, Erwann P, Darque, Albert, Jouve, Elisabeth, Loret, Elvenn A, Nicolino-Brunet, Corinne, Morange, Sophie, Castanier, Elisabeth, Casanova, Josiane, Caloustian, Christine, Bornet, Charléric, Coussirou, Julie, Boussetta, Jihen, Couallier, Vincent, Blin, Olivier, Dussol, Bertrand, Ravaux, Isabelle

“…A Tat Oyi vaccine preparation was administered with informed consent to 48 long-term HIV-1 infected volunteers whose viral loads had been suppressed by…”
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Reservoir cells no longer detectable after a heterologous SHIV challenge with the synthetic HIV-1 Tat Oyi vaccine by Watkins, Jennifer D, Lancelot, Sophie, Campbell, Grant R, Esquieu, Didier, de Mareuil, Jean, Opi, Sandrine, Annappa, Sylvie, Salles, Jean-Pierre, Loret, Erwann P

“…Extra-cellular roles of Tat might be the main cause of maintenance of HIV-1 infected CD4 T cells or reservoir cells. We developed a synthetic vaccine based on…”
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A Monoclonal Antibody Directed against a Conformational Epitope of the HIV-1 Trans-activator (Tat) Protein Neutralizes Cross-clade by Mediouni, Sonia, Watkins, Jennifer D., Pierres, Michel, Bole, Angélique, Loret, Erwann P., Baillat, Gilbert

“…The identification of a neutralizing mAb against extracellular HIV-1 transactivator of transcription (Tat) is important for the development of an efficient…”
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Multimodality vaccination against clade C SHIV: Partial protection against mucosal challenges with a heterologous tier 2 virus by Lakhashe, Samir K, Byrareddy, Siddappa N, Zhou, Mingkui, Bachler, Barbara C, Hemashettar, Girish, Hu, Shiu-Lok, Villinger, Francois, Else, James G, Stock, Shannon, Lee, Sandra J, Vargas-Inchaustegui, Diego A, Cofano, Egidio Brocca, Robert-Guroff, Marjorie, Johnson, Welkin E, Polonis, Victoria R, Forthal, Donald N, Loret, Erwann P, Rasmussen, Robert A, Ruprecht, Ruth M

“…Highlights • Vaccine-induced protection against heterologous tier 2 SHIV-C challenge. • Protection was associated with anamnestic cellular and ADCC responses…”
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Differential induction of rat neuronal excitotoxic cell death by human immunodeficiency virus type 1 clade B and C tat proteins by Campbell, Grant R, Watkins, Jennifer D, Loret, Erwann P, Spector, Stephen A

“…In the absence of effective antiretroviral therapy, infection with clade B human immunodeficiency virus (HIV-1) infection commonly progresses to AIDS dementia…”
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Erratum to: Intradermal injection of a Tat Oyi-based therapeutic HIV vaccine reduces of 1.5 log copies/mL the HIV RNA rebound median and no HIV DNA rebound following cART interruption in a phase I/II randomized controlled clinical trial by Loret, Erwann P, Darque, Albert, Jouve, Elisabeth, Loret, Elvenn A, Nicolino-Brunet, Corinne, Morange, Sophie, Castanier, Elisabeth, Casanova, Josiane, Caloustian, Christine, Bornet, Charléric, Coussirou, Julie, Boussetta, Jihen, Couallier, Vincent, Blin, Olivier, Dussol, Bertrand, Ravaux, Isabelle

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Structure-function relationships of the HIV-1 Tat protein by Loret, Erwann P

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Tat mutations in an African cohort that do not prevent transactivation but change its immunogenic properties by Campbell, Grant R, Senkaali, David, Watkins, Jennifer, Esquieu, Didier, Opi, Sandrine, Yirrell, David L, Kaleebu, Pontiano, Loret, Erwann P

“…Abstract Humoral responses against extra-cellular HIV-1 Tat may be beneficial as Tat has been implicated in the viral pathogenesis associated with HIV-1…”
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