Search Results - "Lorenzo, I."

An Atomic Structure of the Human Spliceosome by Zhang, Xiaofeng, Yan, Chuangye, Hang, Jing, Finci, Lorenzo I., Lei, Jianlin, Shi, Yigong

“…Mechanistic understanding of pre-mRNA splicing requires detailed structural information on various states of the spliceosome. Here we report the cryo electron…”
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The Crystal Structure of Netrin-1 in Complex with DCC Reveals the Bifunctionality of Netrin-1 As a Guidance Cue by Finci, Lorenzo I., Krüger, Nina, Sun, Xiaqin, Zhang, Jie, Chegkazi, Magda, Wu, Yu, Schenk, Gundolf, Mertens, Haydyn D.T., Svergun, Dmitri I., Zhang, Yan, Wang, Jia-huai, Meijers, Rob

“…Netrin-1 is a guidance cue that can trigger either attraction or repulsion effects on migrating axons of neurons, depending on the repertoire of receptors…”
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The cryo-EM structure of the SF3b spliceosome complex bound to a splicing modulator reveals a pre-mRNA substrate competitive mechanism of action by Finci, Lorenzo I, Zhang, Xiaofeng, Huang, Xiuliang, Zhou, Qiang, Tsai, Jennifer, Teng, Teng, Agrawal, Anant, Chan, Betty, Irwin, Sean, Karr, Craig, Cook, Andrew, Zhu, Ping, Reynolds, Dominic, Smith, Peter G, Fekkes, Peter, Buonamici, Silvia, Larsen, Nicholas A

“…Somatic mutations in spliceosome proteins lead to dysregulated RNA splicing and are observed in a variety of cancers. These genetic aberrations may offer a…”
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Intermediary processes in Hispanic/Latinx/o youths' coping responses to cultural stressors by Lorenzo‐Blanco, Elma I., Henriquez, Kimberly L., Stein, Gabriela Livas

“…Cultural stressors related to racism, xenophobia, and navigating bicultural contexts can compromise the healthy development of Hispanic/Latinx/o (H/L) youth…”
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Agency does not mean freedom. Cape Verdean street children and the politics of children's agency by Bordonaro, Lorenzo I.

“…At a time when children and youth are heralded by scholars and international organisations alike as active agents in the construction of their own lives and as…”
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Ambiguous agency: critical perspectives on social interventions with children and youth in Africa by Bordonaro, Lorenzo I., Payne, Ruth

“…African children and youth, especially those growing up in expanding urban areas throughout the African Continent, are increasingly identified in academic…”
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Self‐reported allergy to penicillin and clindamycin administration may be risk factors for dental implant failure: A systematic review, meta‐analysis and delabeling protocol by Edibam, Naushad R., Lorenzo‐Pouso, Alejandro I., Caponio, Vito Carlo Alberto

“…Objective Growing evidence is highlighting the inefficacy of clindamycin as an effective substitute to amoxicillin in patients self‐reporting a penicillin…”
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Association between periodontitis and medication‐related osteonecrosis of the jaw: A systematic review and meta‐analysis by Lorenzo‐Pouso, Alejandro I., Pérez‐Sayáns, Mario, Chamorro‐Petronacci, Cintia, Gándara‐Vila, Pilar, López‐Jornet, Pía, Carballo, Javier, García‐García, Abel

“…Consensus has yet to be reached about the prevention and treatment of medication‐related osteonecrosis of the jaw (MRONJ), which is a treatment sequela of…”
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Modelling the impact of salt reduction policies on hypertension in Portugal by Lorenzo i Sunyer, N, Severo, M, Gregório, MJ, Lopes, C

“…Salt reduction policies are identified as effective; however, the assessment of their impact in European countries has been underexplored. The aim of this…”
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Longitudinal change in adolescent hope among recent immigrant Latinx adolescents: Links with adolescent and parent cultural stress, family functioning, emotional well‐being, and behavioral health by Lorenzo‐Blanco, Elma I., Zhang, Minyu, Cobb, Cory, Meca, Alan, Szapocznik, José, Unger, Jennifer B., Cano, Miguel Ángel, Schwartz, Seth J.

“…Adolescent hope can promote the emotional and behavioral well‐being of Latinx families. Positive family functioning may foster adolescent hope, whereas…”
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Zooplankton species composition is linked to ocean transport in the Northern California Current by KEISTER, J.E, DI LORENZO, E, MORGAN, C.A, COMBES, V, PETERSON, W.T

“…In the Northern California Current (NCC), zooplankton communities show interannual and multiyear shifts in species dominance that are tracked by survival of…”
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Structure of the SHOC2–MRAS–PP1C complex provides insights into RAF activation and Noonan syndrome by Bonsor, Daniel A., Alexander, Patrick, Snead, Kelly, Hartig, Nicole, Drew, Matthew, Messing, Simon, Finci, Lorenzo I., Nissley, Dwight V., McCormick, Frank, Esposito, Dominic, Rodriguez-Viciana, Pablo, Stephen, Andrew G., Simanshu, Dhirendra K.

“…SHOC2 acts as a strong synthetic lethal interactor with MEK inhibitors in multiple KRAS cancer cell lines. SHOC2 forms a heterotrimeric complex with MRAS and…”
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Longitudinal Trajectories of Family Functioning Among Recent Immigrant Adolescents and Parents: Links With Adolescent and Parent Cultural Stress, Emotional Well‐Being, and Behavioral Health by Lorenzo‐Blanco, Elma I., Meca, Alan, Piña‐Watson, Brandy, Zamboanga, Byron L., Szapocznik, José, Cano, Miguel Ángel, Cordova, David, Unger, Jennifer B., Romero, Andrea, Des Rosiers, Sabrina E., Soto, Daniel W., Villamar, Juan A., Pattarroyo, Monica, Lizzi, Karina M., Schwartz, Seth J.

“…This study examined longitudinal effects of adolescent and parent cultural stress on adolescent and parent emotional well‐being and health behaviors via…”
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Defective chaperone-mediated autophagy is a hallmark of joint disease in patients with knee osteoarthritis by Lorenzo-Gómez, I., Nogueira-Recalde, U., García-Domínguez, C., Oreiro-Villar, N., Lotz, M., Pinto-Tasende, J.A., Blanco, F.J., Caramés, B.

“…Defects in autophagy contribute to joint aging and Osteoarthritis (OA). Identifying specific autophagy types could be useful for developing novel treatments…”
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Total Body Water and Intracellular Water Relationships with Muscle Strength, Frailty and Functional Performance in an Elderly Population. A Cross-Sectional Study by Serra-Prat, Mateu, Lorenzo, I., Palomera, E., Ramírez, S., Yébenes, J. C.

“…Background As a person ages, total body water (TBW), intracellular water (ICW), muscle mass and muscle strength tend to decline. The decline in ICW may reflect…”
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Distinct co‐occurrence patterns of acculturation and perceived context of reception between weekdays and weekends among Hispanic college students by Lee, Tae Kyoung, Meca, Alan, Schwartz, Seth J., Cobb, Cory L., Song, Hana, Duque, Maria, Stuart, Jaimee, Lorenzo‐Blanco, Elma I.

“…Objective The present study was designed to examine distinct co‐occurrence patterns of acculturation and perceived context of reception between weekdays and…”
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Efficacy of topical agents in oral mucositis prevention: Systematic review and network meta‐analysis by Coppini, Martina, Caponio, Vito Carlo Alberto, Mauceri, Rodolfo, Bizzoca, Maria Eleonora, Laino, Luigi, Lorenzo‐Pouso, Alejandro I., Russo, Diana, Troiano, Giuseppe, Silva, Fábio França Vieira E., Lo Muzio, Lorenzo, Campisi, Giuseppina

“…Background Oral mucositis (OM) is considered one of the most common side effects of patients undergoing cancer therapy. OM prevention plays a crucial role in…”
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Caspase 3 and Cleaved Caspase 3 Expression in Tumorogenesis and Its Correlations with Prognosis in Head and Neck Cancer: A Systematic Review and Meta-Analysis by Silva, Fábio, Padín-Iruegas, María, Caponio, Vito, Lorenzo-Pouso, Alejandro, Saavedra-Nieves, Paula, Chamorro-Petronacci, Cintia, Suaréz-Peñaranda, José, Pérez-Sayáns, Mario

“…Head and neck cancer (HNC) is an ascending and agressive disease. The search for new molecular markers is emerging to solve difficulties in diagnosis, risk…”
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Dynamic Transition Patterns in Acculturation Among Hispanic Adolescents by Lee, Tae Kyoung, Meca, Alan, Unger, Jennifer B., Zamboanga, Byron L., Baezconde‐Garbanati, Lourdes, Gonzales‐Backen, Melinda, Lorenzo‐Blanco, Elma I., Cano, Miguel Á., Des Rosiers, Sabrina E., Soto, Daniel W., Villamar, Juan A., Pattarroyo, Monica, Lizzi, Karina M., Szapocznik, José, Schwartz, Seth J.

“…Acculturation consists of multiple domains (i.e., cultural practices, identifications, and values). However, less is known about how acculturation processes…”
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Quantitative proteomics in medication‐related osteonecrosis of the jaw: A proof‐of‐concept study by Lorenzo‐Pouso, Alejandro I., Bravo, Susana B., Carballo, Javier, Chantada‐Vázquez, María del Pilar, Bagán, José, Bagán, Leticia, Chamorro‐Petronacci, Cintia M., Conde‐Amboage, Mercedes, López‐López, Rafael, García‐García, Abel, Pérez‐Sayáns, Mario

“…Objective Medication‐related osteonecrosis of the jaw (MRONJ) is a paradoxical effect associated with bone‐modifying agents (BMAs) and other drugs. Currently,…”
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