Search Results - "Lorenzi, Julio C. Cetrulo"
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Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies
Published in Cell (20-08-2020)“…Neutralizing antibody responses to coronaviruses mainly target the receptor-binding domain (RBD) of the trimeric spike. Here, we characterized polyclonal…”
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Journal Article -
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A broadly neutralizing macaque monoclonal antibody against the HIV-1 V3-Glycan patch
Published in eLife (21-10-2020)“…A small fraction of HIV-1- infected humans develop broadly neutralizing antibodies (bNAbs) against HIV-1 that protect macaques from simian immunodeficiency HIV…”
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Journal Article -
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A naturally arising broad and potent CD4-binding site antibody with low somatic mutation
Published in Science advances (12-08-2022)“…The induction of broadly neutralizing antibodies (bNAbs) is a potential strategy for a vaccine against HIV-1. However, most bNAbs exhibit features such as…”
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Journal Article