Search Results - "Lorenzi, Gayle"

Mediation of the Effect of Glycemia on the Risk of CVD Outcomes in Type 1 Diabetes: The DCCT/EDIC Study by Bebu, Ionut, Braffett, Barbara H, Orchard, Trevor J, Lorenzi, Gayle M, Lachin, John M

“…The Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) study has demonstrated the major role of…”
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Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study at 30 Years: Advances and Contributions by NATHAN, David M, BAYLESS, Margaret, CLEARY, Patricia, GENUTH, Saul, GUBITOSI-KLUG, Rose, LACHIN, John M, LORENZI, Gayle, ZINMAN, Bernard

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Risk of Foot Ulcer and Lower-Extremity Amputation Among Participants in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study by Boyko, Edward J, Zelnick, Leila R, Braffett, Barbara H, Pop-Busui, Rodica, Cowie, Catherine C, Lorenzi, Gayle M, Gubitosi-Klug, Rose, Zinman, Bernard, de Boer, Ian H

“…Intensive glycemic control reduces the risk of kidney, retinal, and neurologic complications in type 1 diabetes (T1D), but whether it reduces the risk of…”
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Evaluating the Role of Epigenetic Histone Modifications in the Metabolic Memory of Type 1 Diabetes by FENG MIAO, ZHUO CHEN, LORENZI, Gayle, KOLTERMAN, Orville, SUN, Wanjie, LACHIN, John M, NATARAJAN, Rama, GENUTH, Saul, PATERSON, Andrew, LINGXIAO ZHANG, XIWEI WU, SIERRA MIN LI, CLEARY, Patricia, RIGGS, Arthur, HARLAN, David M

“…We assessed whether epigenetic histone posttranslational modifications are associated with the prolonged beneficial effects (metabolic memory) of intensive…”
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Cognitive performance declines in older adults with type 1 diabetes: results from 32 years of follow-up in the DCCT and EDIC Study by Jacobson, Alan M, Ryan, Christopher M, Braffett, Barbara H, Gubitosi-Klug, Rose A, Lorenzi, Gayle M, Luchsinger, José A, Trapani, Victoria R, Bebu, Ionut, Chaytor, Naomi, Hitt, Susan M, Farrell, Kaleigh, Lachin, John M

“…With improved treatment, individuals with type 1 diabetes are living longer but there is limited information on the effects of type 1 diabetes on cognitive…”
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Intensive Glycemic Management Is Associated With Reduced Retinal Structure Abnormalities on Ocular Coherence Tomography in the DCCT/EDIC Study by Blodi, Barbara, Gardner, Thomas W, Gao, Xiaoyu, Sun, Jennifer K, Lorenzi, Gayle M, Olmos de Koo, Lisa C, Das, Arup, White, Neil H, Gubitosi-Klug, Rose A, Aiello, Lloyd P, Bebu, Ionut

“…To investigate quantitative and qualitative changes in retinal structure using optical coherence tomography (OCT) and their associations with systemic or other…”
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Optimal Frequency of Urinary Albumin Screening in Type 1 Diabetes by Perkins, Bruce A, Bebu, Ionut, de Boer, Ian H, Molitch, Mark, Zinman, Bernard, Bantle, John, Lorenzi, Gayle M, Nathan, David M, Lachin, John M

“…Kidney disease screening recommendations include annual urine testing for albuminuria after 5 years' duration of type 1 diabetes. We aimed to determine a…”
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Associations of Kidney Tubular Biomarkers With Incident Macroalbuminuria and Sustained Low eGFR in DCCT/EDIC by Limonte, Christine P, Gao, Xiaoyu, Bebu, Ionut, Seegmiller, Jesse C, Karger, Amy B, Lorenzi, Gayle M, Molitch, Mark, Karanchi, Harsha, Perkins, Bruce A, de Boer, Ian H

“…Tubulointerstitial injury contributes to diabetic kidney disease (DKD) progression. We tested tubular biomarker associations with DKD development in type 1…”
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Relationships Between the Cumulative Incidences of Long-term Complications in Type 1 Diabetes: The DCCT/EDIC Study by Bebu, Ionut, Braffett, Barbara H, de Boer, Ian H, Aiello, Lloyd P, Bantle, John P, Lorenzi, Gayle M, Herman, William H, Gubitosi-Klug, Rose A, Perkins, Bruce A, Lachin, John M, Molitch, Mark E

“…To describe the relationships between the cumulative incidences of long-term complications in individuals with type 1 diabetes (T1D) and assess whether…”
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An Observational Study of the Equivalence of Age and Duration of Diabetes to Glycemic Control Relative to the Risk of Complications in the Combined Cohorts of the DCCT/EDIC Study by Bebu, Ionut, Braffett, Barbara H, Schade, David, Sivitz, William, Malone, John I, Pop-Busui, Rodica, Lorenzi, Gayle M, Lee, Pearl, Trapani, Victoria R, Wallia, Amisha, Herman, William H, Lachin, John M

“…This epidemiological analysis of the pooled Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC)…”
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Hearing Impairment and Type 1 Diabetes in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Cohort by Schade, David S, Lorenzi, Gayle M, Braffett, Barbara H, Gao, Xiaoyu, Bainbridge, Kathleen E, Barnie, Annette, Cruickshanks, Karen J, Dalton, Dayna, Diminick, Lisa, Gubitosi-Klug, Rose, Kramer, John R, Lachin, John M, Larkin, Mary E, Cowie, Catherine C

“…To evaluate the prevalence of hearing impairment in participants with type 1 diabetes enrolled in the Diabetes Control and Complications Trial/Epidemiology of…”
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Brain Structure Among Middle-aged and Older Adults With Long-standing Type 1 Diabetes in the DCCT/EDIC Study by Jacobson, Alan M, Braffett, Barbara H, Erus, Guray, Ryan, Christopher M, Biessels, Geert J, Luchsinger, José A, Bebu, Ionut, Gubitosi-Klug, Rose A, Desiderio, Lisa, Lorenzi, Gayle M, Trapani, Victoria R, Lachin, John M, Bryan, R Nick, Habes, Mohamad, Nasrallah, Ilya M

“…Individuals with type 1 diabetes mellitus (T1DM) are living to ages when neuropathological changes are increasingly evident. We hypothesized that middle-aged…”
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Retinopathy During the First 5 Years of Type 1 Diabetes and Subsequent Risk of Advanced Retinopathy by Malone, John I, Gao, Xiaoyu, Lorenzi, Gayle M, Raskin, Philip, White, Neil H, Hainsworth, Dean P, Das, Arup, Tamborlane, William, Wallia, Amisha, Aiello, Lloyd P, Bebu, Ionut

“…To determine whether individuals with type 1 diabetes (T1D) who develop any retinopathy at any time prior to 5 years of diabetes duration have an increased…”
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Utility of using electrocardiogram measures of heart rate variability as a measure of cardiovascular autonomic neuropathy in type 1 diabetes patients by Pop‐Busui, Rodica, Backlund, Jye‐Yu C, Bebu, Ionut, Braffett, Barbara H, Lorenzi, Gayle, White, Neil H, Lachin, John M, Soliman, Elsayed Z

“…Aims/Introduction Cardiovascular autonomic neuropathy (CAN) is a predictor of cardiovascular disease and mortality. Cardiovascular reflex tests (CARTs) are the…”
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Risk Factors for Longitudinal Resting Heart Rate and Its Associations With Cardiovascular Outcomes in the DCCT/EDIC Study by Keshavarzi, Sareh, Braffett, Barbara H, Pop-Busui, Rodica, Orchard, Trevor J, Soliman, Elsayed Z, Lorenzi, Gayle M, Barnie, Annette, Karger, Amy B, Gubitosi-Klug, Rose A, Dagogo-Jack, Samuel, Paterson, Andrew D

“…Individuals with diabetes have higher resting heart rate compared with those without, which may be predictive of long-term cardiovascular disease (CVD) risk…”
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Moderation of the effect of glycemia on the risk of cardiovascular disease in type 1 diabetes: The DCCT/EDIC study by Bebu, Ionut, Braffett, Barbara H., Orchard, Trevor J., Lorenzi, Gayle M., Nathan, David M., Herman, William H., Lachin, John M.

“…We assessed whether and to what extent established cardiovascular disease (CVD) risk factors moderate (enhance/reduce) the effect of hyperglycemia on CVD…”
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Utility of the NIH Toolbox Cognition Battery in middle to older aged adults with longstanding type 1 diabetes: The DCCT/EDIC study by Chaytor, Naomi S., Trapani, Victoria R., Braffett, Barbara H., Fonseca, Luciana M., Lorenzi, Gayle M., Gubitosi-Klug, Rose A., Hitt, Susan, Farrell, Kaleigh, Jacobson, Alan M., Ryan, Christopher M.

“…Objective: Adults with type 1 diabetes (T1D) face an increased risk for cognitive decline and dementia. Diabetes-related and vascular risk factors have been…”
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Comparison of central laboratory HbA1c measurements obtained from a capillary collection versus a standard venous whole blood collection in the GRADE and EDIC studies by Nathan, David M, Krause-Steinrauf, Heidi, Braffett, Barbara H, Arends, Valerie L, Younes, Naji, McGee, Paula, Lund, Claire, Johnson, Mary, Lorenzi, Gayle, Gao, Xiaoyu, Steffes, Michael W, Lachin, John M

“…We compared HbA1c values obtained from capillary blood collection kits versus venous whole blood collections in study participants with type 1 or type 2…”
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286-OR: Biomedical Predictors of Cognitive Decline in Older Participants with T1DM: Longitudinal Follow-Up of the DCCT/EDIC Cohort by JACOBSON, ALAN M., RYAN, CHRISTOPHER M., BRAFFETT, BARBARA H., GUBITOSI-KLUG, ROSE, LORENZI, GAYLE M., LUCHSINGER, JOSE A., TRAPANI, VICTORIA R., BEBU, IONUT, CHAYTOR, NAOMI, HITT, SUSAN M., FARRELL, KALEIGH, LACHIN, JOHN M.

“…DCCT/EDIC participants have been followed for an average of 32 years (N=1,054; mean age 60±7 years; duration T1DM 38±5 years). To evaluate cognitive function…”
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Screening eye exams in youth with type 1 diabetes under 18 years of age: Once may be enough? by Gubitosi‐Klug, Rose A., Bebu, Ionut, White, Neil H., Malone, John, Miller, Ryan, Lorenzi, Gayle M., Hainsworth, Dean P., Trapani, Victoria R., Lachin, John M., Tamborlane, William V.

“…Case series and registry data suggest that diabetic retinopathy requiring treatment is rare in youth with type 1 diabetes (T1D) prior to 18 years of age. We…”
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