Search Results - "Lorenzetto, Erika"
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1
The Potential Role of Rho GTPases in Alzheimer's Disease Pathogenesis
Published in Molecular neurobiology (01-10-2014)“…Alzheimer's disease (AD) is characterized by a wide loss of synapses and dendritic spines. Despite extensive efforts, the molecular mechanisms driving this…”
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2
Sos1 Regulates Macrophage Podosome Assembly and Macrophage Invasive Capacity
Published in The Journal of immunology (1950) (15-11-2015)“…Podosomes are protrusive structures implicated in macrophage extracellular matrix degradation and three-dimensional migration through cell barriers and the…”
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3
Rac1 activation links tau hyperphosphorylation and Aβ dysmetabolism in Alzheimer's disease
Published in Acta neuropathologica communications (13-07-2018)“…One of the earliest pathological features characterizing Alzheimer's disease (AD) is the loss of dendritic spines. Among the many factors potentially mediating…”
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4
Rac1 selective activation improves retina ganglion cell survival and regeneration
Published in PloS one (29-05-2013)“…In adult mammals, after optic nerve injury, retinal ganglion cells (RGCs) do not regenerate their axons and most of them die by apoptosis within a few days…”
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5
Genetic perturbation of postsynaptic activity regulates synapse elimination in developing cerebellum
Published in Proceedings of the National Academy of Sciences - PNAS (22-09-2009)“…In many parts of the vertebrate nervous system, synaptic connections are remodeled during early postnatal life. Neural activity plays an important role in…”
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6
A new monoclonal antibody detects downregulation of protein tyrosine phosphatase receptor type γ in chronic myeloid leukemia patients
Published in Journal of hematology and oncology (21-06-2017)“…Protein tyrosine phosphatase receptor gamma (PTPRG) is a ubiquitously expressed member of the protein tyrosine phosphatase family known to act as a tumor…”
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7
Impaired nerve regeneration in reeler mice after peripheral nerve injury
Published in The European journal of neuroscience (01-01-2008)“…Reelin, an extracellular matrix protein, plays an important role in the regulation of neuronal migration and cortical lamination in the developing brain…”
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8
Glutamatergic neurons induce expression of functional glutamatergic synapses in primary myotubes
Published in PloS one (09-02-2012)“…The functioning of the nervous system depends upon the specificity of its synaptic contacts. The mechanisms triggering the expression of the appropriate…”
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9
Astrocytes Regulate the Expression of Insulin-Like Growth Factor 1 Receptor (IGF1-R) in Primary Cortical Neurons During In Vitro Senescence
Published in Journal of molecular neuroscience (01-03-2010)“…The role of insulin-like growth factor 1 (IGF1) pathway as regulator of aging and age-related diseases is increasingly recognized. Recent evidence has been…”
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10
Reelin is transiently expressed in the peripheral nerve during development and is upregulated following nerve crush
Published in Molecular and cellular neuroscience (01-05-2006)“…Reelin is an extracellular matrix protein which is critical for the positioning of migrating post-mitotic neurons and the laminar organization of several brain…”
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11
BID and the α-bisabolol-triggered cell death program: converging on mitochondria and lysosomes
Published in Cell death & disease (26-11-2019)“…α-Bisabolol (BSB) is a plant-derived sesquiterpene alcohol able to trigger regulated cell death in transformed cells, while deprived of the general toxicity in…”
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12
β-Amyloid-aluminum complex alters cytoskeletal stability and increases ROS production in cortical neurons
Published in Neurochemistry international (01-04-2013)“…Several lines of evidence have supported the potential involvement of metal ions in the etiology of Alzheimer’s Disease (AD). However, the molecular mechanisms…”
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13
Distribution of different isoforms of receptor protein tyrosine phosphatase γ (Ptprg-RPTP γ) in adult mouse brain: upregulation during neuroinflammation
Published in Brain structure & function (01-05-2014)“…The receptor protein tyrosine phosphatase γ (Ptprg-RPTPγ) is a receptor protein widely expressed in many tissues, including the central nervous system (CNS)…”
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14
HOMECAT: consensus homologs mapping for interspecific knowledge transfer and functional genomic data integration
Published in Bioinformatics (15-06-2013)“…Comparative studies are encouraged by the fast increase of data availability from the latest high-throughput techniques, in particular from functional genomic…”
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15
Therapeutic targeting of Lyn kinase to treat chorea-acanthocytosis
Published in Acta neuropathologica communications (03-05-2021)“…Chorea-Acanthocytosis (ChAc) is a devastating, little understood, and currently untreatable neurodegenerative disease caused by VPS13A mutations. Based on our…”
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16
Distribution of different isoforms of receptor protein tyrosine phosphatase [gamma] (Ptprg-RPTP [gamma]) in adult mouse brain: upregulation during neuroinflammation
Published in Brain Structure and Function (01-05-2014)“…The receptor protein tyrosine phosphatase γ (Ptprg-RPTPγ) is a receptor protein widely expressed in many tissues, including the central nervous system (CNS)…”
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17
Rho GTPase-dependent plasticity of dendritic spines in the adult brain
Published in Frontiers in cellular neuroscience (23-05-2013)“…Brain activity is associated with structural changes in the neural connections. However, in vivo imaging of the outer cortical layers has shown that dendritic…”
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18
A new monoclonal antibody detects downregulation of protein tyrosine phosphatase receptor type [gamma] in chronic myeloid leukemia patients
Published in Journal of hematology and oncology (21-06-2017)“…Background Protein tyrosine phosphatase receptor gamma (PTPRG) is a ubiquitously expressed member of the protein tyrosine phosphatase family known to act as a…”
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19
Correction: Glutamatergic Neurons Induce Expression of Functional Glutamatergic Synapses in Primary Myotubes
Published in PloS one (29-03-2012)Get full text
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20
Rac1 activation links tau hyperphosphorylation and A[beta] dysmetabolism in Alzheimer's disease
Published in Acta neuropathologica communications (13-07-2018)“…One of the earliest pathological features characterizing Alzheimer's disease (AD) is the loss of dendritic spines. Among the many factors potentially mediating…”
Get full text
Journal Article