Search Results - "Lorenzen, M"

Biogenesis and Function of Circular RNAs in Health and in Disease by Haddad, George, Lorenzen, Johan M

“…Circular RNAs (circRNAs) are a class of non-coding RNA that were previously thought to be insignificant byproducts of splicing errors. However, recent advances…”
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Functional diversity affects decomposition processes in experimental grasslands by Scherer-Lorenzen, M

“…1. A number of biodiversity experiments have shown that plant diversity plays a significant role for ecosystem functioning. However, diversity effects on…”
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Vascular and circulating microRNAs in renal ischaemia–reperfusion injury by Lorenzen, Johan M.

“…Ischaemia–reperfusion (I/R) injury of the kidney is a major cause of acute kidney injury. It may result in worsening or even loss of organ function. Transient…”
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Circulating and Urinary microRNAs in Kidney Disease by Lorenzen, Johan M, Thum, Thomas

“…microRNAs are small, noncoding RNAs that control gene/protein expression through target messengerRNA degradation and/or inhibition of protein synthesis. An…”
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Altered glycosylation of IgG4 promotes lectin complement pathway activation in anti-PLA2R1-associated membranous nephropathy by Haddad, George, Lorenzen, Johan M, Ma, Hong, de Haan, Noortje, Seeger, Harald, Zaghrini, Christelle, Brandt, Simone, Kölling, Malte, Wegmann, Urs, Kiss, Bence, Pál, Gábor, Gál, Péter, Wüthrich, Rudolf P, Wuhrer, Manfred, Beck, Laurence H, Salant, David J, Lambeau, Gérard, Kistler, Andreas D

“…Primary membranous nephropathy (pMN) is a leading cause of nephrotic syndrome in adults. In most cases, this autoimmune kidney disease is associated with…”
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MicroRNAs as mediators and therapeutic targets in chronic kidney disease by Lorenzen, Johan M., Haller, Hermann, Thum, Thomas

“…Micro (mi)RNAs are short, noncoding nucleotides that target and regulate messenger RNA at the post-transcriptional level. In this Review, Lorenzen and…”
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Diagnostic and Therapeutic Potential of microRNAs in Acute Kidney Injury by Brandenburger, Timo, Lorenzen, Johan M.

“…During hospital stay, about 20% of adult patients experience an episode of acute kidney injury (AKI), which is characterized by a rapid decrease in kidney…”
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Therapeutic miR-21 Silencing Ameliorates Diabetic Kidney Disease in Mice by Kölling, Malte, Kaucsar, Tamas, Schauerte, Celina, Hübner, Anika, Dettling, Angela, Park, Joon-Keun, Busch, Martin, Wulff, Xaver, Meier, Matthias, Scherf, Kristian, Bukosza, Nóra, Szénási, Gábor, Godó, Mária, Sharma, Amit, Heuser, Michael, Hamar, Peter, Bang, Claudia, Haller, Hermann, Thum, Thomas, Lorenzen, Johan M.

“…Diabetic nephropathy is the main cause of end-stage renal disease. MicroRNAs are powerful regulators of the genome, and global expression profiling revealed…”
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Diagnostic and prognostic impact of six circulating microRNAs in acute coronary syndrome by Widera, Christian, Gupta, Shashi K, Lorenzen, Johan M, Bang, Claudia, Bauersachs, Johann, Bethmann, Kerstin, Kempf, Tibor, Wollert, Kai C, Thum, Thomas

“…Abstract Circulating microRNAs may have diagnostic potential in acute coronary syndrome (ACS). Previous studies, however, were based on low patient numbers and…”
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MicroRNA-24 antagonism prevents renal ischemia reperfusion injury by Lorenzen, Johan M, Kaucsar, Tamas, Schauerte, Celina, Schmitt, Roland, Rong, Song, Hübner, Anika, Scherf, Kristian, Fiedler, Jan, Martino, Filippo, Kumarswamy, Regalla, Kölling, Malte, Sörensen, Inga, Hinz, Hebke, Heineke, Joerg, van Rooij, Eva, Haller, Hermann, Thum, Thomas

“…Ischemia-reperfusion (I/R) injury of the kidney is a major cause of AKI. MicroRNAs (miRs) are powerful regulators of various diseases. We investigated the role…”
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General stabilizing effects of plant diversity on grassland productivity through population asynchrony and overyielding by Hector, A, Hautier, Y, Saner, P, Wacker, L, Bagchi, R, Joshi, J, Scherer-Lorenzen, M, Spehn, E. M, Bazeley-White, E, Weilenmann, M, Caldeira, M. C, Dimitrakopoulos, P. G, Finn, J. A, Huss-Danell, K, Jumpponen, A, Mulder, C. P. H, Palmborg, C, Pereira, J. S, Siamantziouras, A. S. D, Terry, A. C, Troumbis, A. Y, Schmid, B, Loreau, M

“…Insurance effects of biodiversity can stabilize the functioning of multispecies ecosystems against environmental variability when differential species'…”
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The hypoxic kidney: pathogenesis and noncoding RNA-based therapeutic strategies by Haddad, George, Kölling, Malte, Lorenzen, Johan M

“…Acute kidney injury (AKI) is a disease entity of major importance, affecting approximately 6% of all patients on the intensive care unit. The mortality rate…”
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Osteopontin is indispensible for AP1-mediated angiotensin II-related miR-21 transcription during cardiac fibrosis by Lorenzen, Johan M, Schauerte, Celina, Hübner, Anika, Kölling, Malte, Martino, Filippo, Scherf, Kristian, Batkai, Sandor, Zimmer, Karina, Foinquinos, Ariana, Kaucsar, Tamas, Fiedler, Jan, Kumarswamy, Regalla, Bang, Claudia, Hartmann, Dorothee, Gupta, Shashi K, Kielstein, Jan, Jungmann, Andreas, Katus, Hugo A, Weidemann, Frank, Müller, Oliver J, Haller, Hermann, Thum, Thomas

“…Osteopontin (OPN) is a multifunctional cytokine critically involved in cardiac fibrosis. However, the underlying mechanisms are unresolved. Non-coding RNAs are…”
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Circulating miR-210 Predicts Survival in Critically Ill Patients with Acute Kidney Injury by Lorenzen, Johan M, Kielstein, Jan T, Hafer, Carsten, Gupta, Shashi K, Kümpers, Philipp, Faulhaber-Walter, Robert, Haller, Hermann, Fliser, Danilo, Thum, Thomas

“…MicroRNAs (miRNAs) are small ribonucleotides regulating gene expression. MicroRNAs are present in the blood in a remarkably stable form. We tested whether…”
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Urinary miR‐210 as a Mediator of Acute T‐Cell Mediated Rejection in Renal Allograft Recipients by Lorenzen, J. M., Volkmann, I., Fiedler, J., Schmidt, M., Scheffner, I., Haller, H., Gwinner, W., Thum, T.

“…MicroRNAs (miRNAs) are small ribonucleotides regulating gene expression. Circulating miRNAs are remarkably stable in the blood. We tested whether miRNAs are…”
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Cardiac fibrosis revisited by microRNA therapeutics by Thum, Thomas, Lorenzen, Johan M

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Podocytes regulate the glomerular basement membrane protein nephronectin by means of miR-378a-3p in glomerular diseases by Müller-Deile, Janina, Dannenberg, Jan, Schroder, Patricia, Lin, Meei-Hua, Miner, Jeffrey H, Chen, Rongjun, Bräsen, Jan-Hinrich, Thum, Thomas, Nyström, Jenny, Staggs, Lynne Beverly, Haller, Hermann, Fiedler, Jan, Lorenzen, Johan M, Schiffer, Mario

“…The pathophysiology of many proteinuric kidney diseases is poorly understood, and microRNAs (miRs) regulation of these diseases has been largely unexplored…”
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Antagonism of profibrotic microRNA-21 improves outcome of murine chronic renal allograft dysfunction by Schauerte, Celina, Hübner, Anika, Rong, Song, Wang, Shijun, Shushakova, Nelli, Mengel, Michael, Dettling, Angela, Bang, Claudia, Scherf, Kristian, Koelling, Malte, Melk, Anette, Haller, Hermann, Thum, Thomas, Lorenzen, Johan M

“…Chronic renal allograft dysfunction (CAD) is a major limiting factor of long-term graft survival. It is characterized by interstitial fibrosis and tubular…”
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Biodiversity for multifunctional grasslands: equal productivity in high-diversity low-input and low-diversity high-input systems by Weigelt, A., Weisser, W. W., Buchmann, N., Scherer-Lorenzen, M.

“…Modern grassland management seeks to provide many ecosystem services and experimental studies in resource-poor grasslands have shown a positive relationship…”
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Aromatase inhibition attenuates desflurane-induced preconditioning against acute myocardial infarction in male mouse heart in vivo by Jazbutyte, Virginija, Stumpner, Jan, Redel, Andreas, Lorenzen, Johan M, Roewer, Norbert, Thum, Thomas, Kehl, Franz

“…The volatile anesthetic desflurane (DES) effectively reduces cardiac infarct size following experimental ischemia/reperfusion injury in the mouse heart. We…”
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