Search Results - "Lorenzana, Zareeb"
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Transcriptional analysis of cystic fibrosis airways at single-cell resolution reveals altered epithelial cell states and composition
Published in Nature medicine (01-05-2021)“…Cystic fibrosis (CF) is a lethal autosomal recessive disorder that afflicts more than 70,000 people. People with CF experience multi-organ dysfunction…”
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Implications for Extracellular Matrix Interactions With Human Lung Basal Stem Cells in Lung Development, Disease, and Airway Modeling
Published in Frontiers in pharmacology (12-05-2021)“…The extracellular matrix (ECM) is not simply a quiescent scaffold. This three-dimensional network of extracellular macromolecules provides structural,…”
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Derivation of induced pluripotent stem cells from ferret somatic cells
Published in American journal of physiology. Lung cellular and molecular physiology (01-04-2020)“…Ferrets are an attractive mammalian model for several diseases, especially those affecting the lungs, liver, brain, and kidneys. Many chronic human diseases…”
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Neutrophilic inflammation promotes SARS-CoV-2 infectivity and augments the inflammatory responses in airway epithelial cells
Published in Frontiers in immunology (16-03-2023)“…In response to viral infection, neutrophils release inflammatory mediators as part of the innate immune response, contributing to pathogen clearance through…”
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