Search Results - "Lorenz, Viola"

The Importance of Thrombin in Cerebral Injury and Disease by Krenzlin, Harald, Lorenz, Viola, Danckwardt, Sven, Kempski, Oliver, Alessandri, Beat

“…There is increasing evidence that prothrombin and its active derivative thrombin are expressed locally in the central nervous system. So far, little is known…”
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Rap1-GTP–interacting adaptor molecule (RIAM) is dispensable for platelet integrin activation and function in mice by Stritt, Simon, Wolf, Karen, Lorenz, Viola, Vögtle, Timo, Gupta, Shuchi, Bösl, Michael R., Nieswandt, Bernhard

“…Platelet aggregation at sites of vascular injury is essential for hemostasis but also thrombosis. Platelet adhesiveness is critically dependent on…”
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Combined In Vivo Depletion of Glycoprotein VI and C-Type Lectin-Like Receptor 2 Severely Compromises Hemostasis and Abrogates Arterial Thrombosis in Mice by Bender, Markus, May, Frauke, Lorenz, Viola, Thielmann, Ina, Hagedorn, Ina, Finney, Brenda A, Vögtle, Timo, Remer, Katharina, Braun, Attila, Bösl, Michael, Watson, Steve P, Nieswandt, Bernhard

“…OBJECTIVE—Platelet inhibition is a major strategy to prevent acute ischemic cardiovascular and cerebrovascular events, which may, however, be associated with…”
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Rehabilitation in primary care for an ageing population: a secondary analysis from a scoping review of rehabilitation delivery models by Seijas, Vanessa, Maritz, Roxanne, Mishra, Satish, Bernard, Renaldo M, Fernandes, Patricia, Lorenz, Viola, Machado, Barbara, Posada, Ana María, Lugo-Agudelo, Luz Helena, Bickenbach, Jerome, Sabariego, Carla

“…The world population is ageing rapidly. Rehabilitation is one of the most effective health strategies for improving the health and functioning of older…”
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Correction: Rehabilitation in primary care for an ageing population: a secondary analysis from a scoping review of rehabilitation delivery models by Seijas, Vanessa, Maritz, Roxanne, Mishra, Satish, Bernard, Renaldo M, Fernandes, Patricia, Lorenz, Viola, Machado, Barbara, Posada, Ana María, Lugo-Agudelo, Luz Helena, Bickenbach, Jerome, Sabariego, Carla

“…Correction to: BMC Health Services Research (2024) 24:123. https://doi.org/10.1186/s12913-023-10387-w. Copy to clipboard Provided by the Springer Nature…”
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Intersection of phosphate transport, oxidative stress and TOR signalling in Candida albicans virulence by Liu, Ning-Ning, Uppuluri, Priya, Broggi, Achille, Besold, Angelique, Ryman, Kicki, Kambara, Hiroto, Solis, Norma, Lorenz, Viola, Qi, Wanjun, Acosta-Zaldívar, Maikel, Emami, S Noushin, Bao, Bin, An, Dingding, Bonilla, Francisco A, Sola-Visner, Martha, Filler, Scott G, Luo, Hongbo R, Engström, Ylva, Ljungdahl, Per Olof, Culotta, Valeria C, Zanoni, Ivan, Lopez-Ribot, Jose L, Köhler, Julia R

“…Phosphate is an essential macronutrient required for cell growth and division. Pho84 is the major high-affinity cell-surface phosphate importer of…”
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Targeted downregulation of platelet CLEC-2 occurs through Syk-independent internalization by Lorenz, Viola, Stegner, David, Stritt, Simon, Vögtle, Timo, Kiefer, Friedemann, Witke, Walter, Schymeinsky, Jürgen, Watson, Steve P., Walzog, Barbara, Nieswandt, Bernhard

“…Platelet aggregation at sites of vascular injury is not only essential for hemostasis, but may also cause acute ischemic disease states such as myocardial…”
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Developmental differences between newborn and adult mice in response to romiplostim by Sparger, Katherine A., Ramsey, Haley, Lorenz, Viola, Liu, Zhi-Jian, Feldman, Henry A., Li, Nan, Laforest, Tahirih, Sola-Visner, Martha C.

“…Thrombocytopenia is frequent among sick neonates. While most cases are transient, some neonates experience prolonged and severe thrombocytopenia. These infants…”
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The Role of Nurses in Rehabilitation in Primary Health Care for Ageing Populations: A Secondary Analysis from a Scoping Review by Lorenz, Viola, Seijas, Vanessa, Gattinger, Heidrun, Gabriel, Claudia, Langins, Margrieta, Mishra, Satish, Sabariego, Carla

“…With the ageing of the global population and the rise in noncommunicable diseases, there is an increased need for rehabilitation services, especially those…”
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The involvement of thrombin in the pathogenesis of glioblastoma by Krenzlin, Harald, Lorenz, Viola, Alessandri, Beat

“…Prothrombin and its active derivative thrombin are key members of the coagulation system. The only site of extra‐hepatic thrombin expression is the central…”
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Inhibition of Platelet GPVI Protects Against Myocardial Ischemia–Reperfusion Injury by Pachel, Christina, Mathes, Denise, Arias-Loza, Anahi-Paula, Heitzmann, Wolfram, Nordbeck, Peter, Deppermann, Carsten, Lorenz, Viola, Hofmann, Ulrich, Nieswandt, Bernhard, Frantz, Stefan

“…OBJECTIVE—The objective of this study was to investigate the effects of platelet inhibition on myocardial ischemia–reperfusion (IR) injury. APPROACH AND…”
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Cytomegalovirus promotes murine glioblastoma growth via pericyte recruitment and angiogenesis by Krenzlin, Harald, Behera, Prajna, Lorenz, Viola, Passaro, Carmela, Zdioruk, Mykola, Nowicki, Michal O, Grauwet, Korneel, Zhang, Hong, Skubal, Magdalena, Ito, Hirotaka, Zane, Rachel, Gutknecht, Michael, Griessl, Marion B, Ricklefs, Franz, Ding, Lai, Peled, Sharon, Rooj, Arun, James, C David, Cobbs, Charles S, Cook, Charles H, Chiocca, E Antonio, Lawler, Sean E

“…Cytomegalovirus (CMV) has been implicated in glioblastoma (GBM); however, a mechanistic connection in vivo has not been established. The purpose of this study…”
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Platelet Transfusions Can Increase or Decrease the Inflammatory Response and Mortality in a Murine Model of Neonatal Polymicrobial Sepsis by Davenport, Patricia E, Fan, Hsuan-Hao, Nolton, Emily, Feldman, Henry, Lorenz, Viola, Canas, Jorge, Acosta-Zaldivar, Maikel, Yakah, William, Stowell, Sean R, Koehler, Julia, Martin, Camilia, Mager, Donald E, Sola-Visner, Martha

“…Thrombocytopenia affects 18-35% of all neonates in the Neonatal Intensive Care Unit and ~70% of those born extremely prematurely, with sepsis being a frequent…”
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Platelet transfusions in a murine model of neonatal polymicrobial sepsis: Divergent effects on inflammation and mortality by Davenport, Patricia, Fan, Hsuan‐Hao, Nolton, Emily, Feldman, Henry A., Lorenz, Viola, Canas, Jorge, Acosta‐Zaldívar, Maikel, Yakah, William, Arthur, Connie, Martin, Camilia, Stowell, Sean, Koehler, Julia, Mager, Donald, Sola‐Visner, Martha

“…Background Platelet transfusions (PTxs) are often given to septic preterm neonates at high platelet count thresholds in an attempt to reduce bleeding risk…”
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Severity of Thrombocytopenia at the Time of Platelet Transfusion Influences Post-Transfusion Platelet Kinetics and the Effects of Platelets on Plasma Cytokines in a Model of Murine Neonatal Sepsis by Davenport, Patricia, Canas, Jorge, Lorenz, Viola, Liu, Zhi-Jian, Badur, Chiara, Do, Thi Minh Thi, Josephson, Cassandra D, Stowell, Sean R., Sola-Visner, Martha

“…Thrombocytopenia affects 20-30% of neonates admitted to the Neonatal Intensive Care Unit (NICU) and up to 70% of those born extremely prematurely, with sepsis…”
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FcγRIIB on liver sinusoidal endothelial cells is essential for antibody-induced GPVI ectodomain shedding in mice by Stegner, David, Popp, Michael, Lorenz, Viola, Wax, Jacqueline K., Gessner, J. Engelbert, Nieswandt, Bernhard

“…The activating platelet collagen receptor glycoprotein VI (GPVI) is a promising antithrombotic target because of its central role in arterial thrombosis and…”
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Noval Insights into the Role of Platelet Angiogenic Growth Factors on the Regulation of Normal Vascular Development by Liu, Zhi-Jian, Battinelli, Elisabeth, Sparger, Katherine A., Ross, Abigail, Johnson, Kelly Elizabeth, Laforest, Tahirih, Lorenz, Viola, Sola-Visner, Martha

“…The role of platelets as angiogenic regulators has been the subject of intense research over the last decade, and has led to the recognition of platelets as…”
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Development of gates to measure the immature platelet fraction in C57BL/6J mice using the Sysmex XN-V series multispecies hematology analyzer by Davenport, Patricia, Lorenz, Viola, Liu, Zhi-Jian, Feldman, Henry A., Canas, Jorge, Nolton, Emily, Badur, Chiara-Aiyleen, Do, Thi Minh-Thi, Sola-Visner, Martha

“…The immature platelet fraction (IPF) is a measure of newly released platelets, which has been used as a marker of platelet production in multiple human studies…”
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Developmental Stage-Specific Manifestations of Absent TPO/c-MPL Signalling in Newborn Mice by Lorenz, Viola, Ramsey, Haley, Liu, Zhi-Jian, Italiano, Jr, Joseph, Hoffmeister, Karin, Bihorel, Sihem, Mager, Donald, Hu, Zhongbo, Slayton, William B, Kile, Benjamin T, Sola-Visner, Martha, Ferrer-Marin, Francisca

“…Congenital amegakaryocytic thrombocytopaenia (CAMT) is a disorder caused by c-MPL mutations that impair thrombopoietin (TPO) signalling, resulting in a near…”
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Thrombocytopenia is associated with severe retinopathy of prematurity by Cakir, Bertan, Liegl, Raffael, Hellgren, Gunnel, Lundgren, Pia, Sun, Ye, Klevebro, Susanna, Löfqvist, Chatarina, Mannheimer, Clara, Cho, Steve, Poblete, Alexander, Duran, Rubi, Hallberg, Boubou, Canas, Jorge, Lorenz, Viola, Liu, Zhi-Jian, Sola-Visner, Martha C, Smith, Lois Eh, Hellström, Ann

“…Retinopathy of prematurity (ROP) is characterized by abnormal retinal neovascularization in response to vessel loss. Platelets regulate angiogenesis and may…”
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