Search Results - "Lorenz, Svenja M"
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Targeting Ferroptosis: New Hope for As-Yet-Incurable Diseases
Published in Trends in molecular medicine (01-02-2021)“…Attaining control over life and death decisions facilitates the identification of new therapeutic strategies for diseases affected by early cell loss or…”
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Intrinsic and Extrinsic Limitations to the Design and Optimization of Inhibitors of Lipid Peroxidation and Associated Cell Death
Published in Journal of the American Chemical Society (17-08-2022)“…The archetype inhibitors of ferroptosis, ferrostatin-1 and liproxstatin-1, were identified via high-throughput screening of compound libraries for…”
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STING orchestrates the neuronal inflammatory stress response in multiple sclerosis
Published in Cell (25-07-2024)“…Inflammation-induced neurodegeneration is a defining feature of multiple sclerosis (MS), yet the underlying mechanisms remain unclear. By dissecting the…”
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7-Dehydrocholesterol is an endogenous suppressor of ferroptosis
Published in Nature (London) (08-02-2024)“…Ferroptosis is a form of cell death that has received considerable attention not only as a means to eradicate defined tumour entities but also because it…”
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