Search Results - "Lorenz, Susanne"

Identification of non-invasive miRNAs biomarkers for prostate cancer by deep sequencing analysis of urinary exosomes by Rodríguez, Marta, Bajo-Santos, Cristina, Hessvik, Nina P, Lorenz, Susanne, Fromm, Bastian, Berge, Viktor, Sandvig, Kirsten, Linē, Aija, Llorente, Alicia

“…The aim of this study was to identify microRNAs in urinary exosomes that are differently expressed in prostate cancer patients and healthy donors. For this…”
Get full text

Monogenic and polygenic determinants of sarcoma risk: an international genetic study by Ballinger, Mandy L, PhD, Goode, David L, PhD, Ray-Coquard, Isabelle, Prof, James, Paul A, MBChB, Mitchell, Gillian, PhD, Niedermayr, Eveline, BSc, Puri, Ajay, Prof, Schiffman, Joshua D, Prof, Dite, Gillian S, PhD, Cipponi, Arcadi, PhD, Maki, Robert G, Prof, Brohl, Andrew S, MD, Myklebost, Ola, Prof, Stratford, Eva W, PhD, Lorenz, Susanne, PhD, Ahn, Sung-Min, MD, Ahn, Jin-Hee, MD, Kim, Jeong Eun, MD, Shanley, Sue, MD, Beshay, Victoria, PhD, Randall, Robert Lor, Prof, Judson, Ian, Prof, Seddon, Beatrice, PhD, Campbell, Ian G, Prof, Young, Mary-Anne, MSc, Sarin, Rajiv, Prof, Blay, Jean-Yves, Prof, O'Donoghue, Seán I, PhD, Thomas, David M, Prof

“…Summary Background Sarcomas are rare, phenotypically heterogeneous cancers that disproportionately affect the young. Outside rare syndromes, the nature,…”
Get full text

Deep Sequencing the MicroRNA Transcriptome in Colorectal Cancer by Schee, Kristina, Lorenz, Susanne, Worren, Merete Molton, Günther, Clara-Cecilie, Holden, Marit, Hovig, Eivind, Fodstad, Oystein, Meza-Zepeda, Leonardo A, Flatmark, Kjersti

“…Colorectal cancer (CRC) is one of the leading causes of cancer related deaths and the search for prognostic biomarkers that might improve treatment decisions…”
Get full text

All-trans retinoic acid enhances the anti-tumour effects of fimaporfin-based photodynamic therapy by Wong, Judith Jing Wen, Lorenz, Susanne, Selbo, Pål Kristian

“…The vitamin A metabolite all-trans retinoic acid (ATRA; tretinoin) has anticancer potential. However, lack of clinical success has prevented its approval for…”
Get full text

Evaluation of commercial DNA and RNA extraction methods for high-throughput sequencing of FFPE samples by Kresse, Stine H, Namløs, Heidi M, Lorenz, Susanne, Berner, Jeanne-Marie, Myklebost, Ola, Bjerkehagen, Bodil, Meza-Zepeda, Leonardo A

“…Nucleic acid material of adequate quality is crucial for successful high-throughput sequencing (HTS) analysis. DNA and RNA isolated from archival FFPE material…”
Get full text

The Regulatory Landscape of Osteogenic Differentiation by Håkelien, Anne‐Mari, Bryne, Jan Christian, Harstad, Kristine G., Lorenz, Susanne, Paulsen, Jonas, Sun, Jinchang, Mikkelsen, Tarjei S., Myklebost, Ola, Meza‐Zepeda, Leonardo A.

“…Differentiation of osteoblasts from mesenchymal stem cells (MSCs) is an integral part of bone development and homeostasis, and may when improperly regulated…”
Get full text

Intra-lineage Plasticity and Functional Reprogramming Maintain Natural Killer Cell Repertoire Diversity by Pfefferle, Aline, Jacobs, Benedikt, Netskar, Herman, Ask, Eivind Heggernes, Lorenz, Susanne, Clancy, Trevor, Goodridge, Jodie P., Sohlberg, Ebba, Malmberg, Karl-Johan

“…Natural killer (NK) cell repertoires are made up of phenotypically distinct subsets with different functional properties. The molecular programs involved in…”
Get full text

Unscrambling the genomic chaos of osteosarcoma reveals extensive transcript fusion, recurrent rearrangements and frequent novel TP53 aberrations by Lorenz, Susanne, Barøy, Tale, Sun, Jinchang, Nome, Torfinn, Vodák, Daniel, Bryne, Jan-Christian, Håkelien, Anne-Mari, Fernandez-Cuesta, Lynnette, Möhlendick, Birte, Rieder, Harald, Szuhai, Karoly, Zaikova, Olga, Ahlquist, Terje C, Thomassen, Gard O S, Skotheim, Rolf I, Lothe, Ragnhild A, Tarpey, Patrick S, Campbell, Peter, Flanagan, Adrienne, Myklebost, Ola, Meza-Zepeda, Leonardo A

“…In contrast to many other sarcoma subtypes, the chaotic karyotypes of osteosarcoma have precluded the identification of pathognomonic translocations. We here…”
Get full text

Rapid genome editing by CRISPR-Cas9-POLD3 fusion by Reint, Ganna, Li, Zhuokun, Labun, Kornel, Keskitalo, Salla, Soppa, Inkeri, Mamia, Katariina, Tolo, Eero, Szymanska, Monika, Meza-Zepeda, Leonardo A, Lorenz, Susanne, Cieslar-Pobuda, Artur, Hu, Xian, Bordin, Diana L, Staerk, Judith, Valen, Eivind, Schmierer, Bernhard, Varjosalo, Markku, Taipale, Jussi, Haapaniemi, Emma

“…Precision CRISPR gene editing relies on the cellular homology-directed DNA repair (HDR) to introduce custom DNA sequences to target sites. The HDR editing…”
Get full text

Preclinical evaluation of potential therapeutic targets in dedifferentiated liposarcoma by Hanes, Robert, Grad, Iwona, Lorenz, Susanne, Stratford, Eva W, Munthe, Else, Reddy, Chilamakuri Chandra Sekhar, Meza-Zepeda, Leonardo A, Myklebost, Ola

“…Sarcomas are rare cancers with limited treatment options. Patients are generally treated by chemotherapy and/or radiotherapy in combination with surgery, and…”
Get full text

Interpreting climate data visualisations to inform adaptation decisions by Daron, Joseph D., Lorenz, Susanne, Wolski, Piotr, Blamey, Ross C., Jack, Christopher

“…•An online survey examined subjective interpretations of climate data visualisations.•Altering visualisation style and/or information content impacts on…”
Get full text

Multi-omics profiling of longitudinal samples reveals early genomic changes in follicular lymphoma by Bai, Baoyan, Wise, Jillian F., Vodák, Daniel, Nakken, Sigve, Sharma, Ankush, Blaker, Yngvild Nuvin, Brodtkorb, Marianne, Hilden, Vera, Trøen, Gunhild, Ren, Weicheng, Lorenz, Susanne, Lawrence, Michael S., Myklebost, Ola, Kimby, Eva, Pan-Hammarström, Qiang, Steen, Chloé B., Meza-Zepeda, Leonardo A., Beiske, Klaus, Smeland, Erlend B., Hovig, Eivind, Lingjærde, Ole Christian, Holte, Harald, Myklebust, June Helen

“…Follicular lymphoma (FL) is the most common indolent type of B-cell non-Hodgkin lymphoma. Advances in treatment have improved overall survival, but early…”
Get full text

Cdc28 kinase activity regulates the basal transcription machinery at a subset of genes by Chymkowitch, Pierre, Eldholm, Vegard, Lorenz, Susanne, Zimmermann, Christine, Lindvall, Jessica M., Bjørås, Magnar, Meza-Zepeda, Leonardo A., Enserink, Jorrit M.

“…The cyclin-dependent kinase Cdc28 is the master regulator of the cell cycle in Saccharomyces cerevisiae. Cdc28 initiates the cell cycle by activating…”
Get full text

Genome Analysis of Osteosarcoma Progression Samples Identifies FGFR1 Overexpression as a Potential Treatment Target and CHM as a Candidate Tumor Suppressor Gene by Barøy, Tale, Chilamakuri, Chandra S R, Lorenz, Susanne, Sun, Jinchang, Bruland, Øyvind S, Myklebost, Ola, Meza-Zepeda, Leonardo A

“…Osteosarcoma (OS) is the most common primary malignant tumor of bone, showing complex chromosomal rearrangements but with few known consistent changes. Deeper…”
Get full text

Generation and characterization of an immortalized human mesenchymal stromal cell line by Skårn, Magne, Noordhuis, Paul, Wang, Meng-Yu, Veuger, Marjan, Kresse, Stine Henrichson, Egeland, Eivind Valen, Micci, Francesca, Namløs, Heidi Maria, Håkelien, Anne-Mari, Olafsrud, Solveig Mjelstad, Lorenz, Susanne, Haraldsen, Guttorm, Kvalheim, Gunnar, Meza-Zepeda, Leonardo Andrés, Myklebost, Ola

“…Human mesenchymal stromal cells (hMSCs) show great potential for clinical and experimental use due to their capacity to self-renew and differentiate into…”
Get more information

Novel GTF2I - PDGFRB and IKZF1 - TYW1 fusions in pediatric leukemia with normal karyotype by Panagopoulos, Ioannis, Brunetti, Marta, Stoltenberg, Margrethe, Strandabø, Rønnaug A U, Staurseth, Julie, Andersen, Kristin, Kostolomov, Ilyá, Hveem, Tarjei S, Lorenz, Susanne, Nystad, Tove Anita, Flægstad, Trond, Micci, Francesca, Heim, Sverre

“…Many cases of acute lymphoblastic leukemia (ALL) carry visible acquired chromosomal changes of pathogenetic, diagnostic, and prognostic importance…”
Get full text

The visual framing of climate change impacts and adaptation in the IPCC assessment reports by Wardekker, Arjan, Lorenz, Susanne

“…The Intergovernmental Panel on Climate Change (IPCC) is a key source on climate change information. How the IPCC presents and frames this climate information…”
Get full text

Association Analysis of Malic Enzyme 2 Gene Polymorphisms with Idiopathic Generalized Epilepsy by Lenzen, Kirsten P., Heils, Armin, Lorenz, Susanne, Hempelmann, Anne, Sander, Thomas

“…Purpose: Linkage disequilibrium mapping revealed allelic and haplotypic associations between single‐nucleotide polymorphisms (SNPs) of the gene encoding the…”
Get full text

Communicating future climate projections of precipitation change by Daron, Joseph, Lorenz, Susanne, Taylor, Andrea, Dessai, Suraje

“…Understanding how precipitation may change in the future is important for guiding climate change adaptation. Climate models are the primary tools for providing…”
Get full text

Correction to: Communicating future climate projections of precipitation change by Daron, Joseph, Lorenz, Susanne, Taylor, Andrea, Dessai, Suraje

“…A Correction to this paper has been published: https://doi.org/10.1007/s10584-021-03166-1…”
Get full text