Search Results - "Lorentz, Katherine L."
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Mesenchymal Stem Cell-Conditioned Media-Loaded Microparticles Enhance Acute Patency in Silk-Based Vascular Grafts
Published in Bioengineering (Basel) (21-09-2024)“…Coronary artery disease leads to over 360,000 deaths annually in the United States, and off-the-shelf bypass graft options are currently limited and/or have…”
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Extracellular Vesicles Derived from Primary Adipose Stromal Cells Induce Elastin and Collagen Deposition by Smooth Muscle Cells within 3D Fibrin Gel Culture
Published in Bioengineering (Basel) (27-04-2021)“…Macromolecular components of the vascular extracellular matrix (ECM), particularly elastic fibers and collagen fibers, are critical for the proper…”
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Adipose-derived stromal cell secreted factors induce the elastogenesis cascade within 3D aortic smooth muscle cell constructs
Published in Matrix biology plus (01-11-2019)“…Elastogenesis within the medial layer of the aortic wall involves a cascade of events orchestrated primarily by smooth muscle cells, including transcription of…”
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Development of a Semi-Automated, Bulk Seeding Device for Large Animal Model Implantation of Tissue Engineered Vascular Grafts
Published in Frontiers in bioengineering and biotechnology (23-10-2020)“…Vascular tissue engineering is a field of regenerative medicine that restores tissue function to defective sections of the vascular network by bypass or…”
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Bioresorbable silk grafts for small diameter vascular tissue engineering applications: In vitro and in vivo functional analysis
Published in Acta biomaterialia (15-03-2020)“…The success of tissue-engineered vascular graft (TEVG) predominantly relies on the selection of a suitable biomaterial and graft design. Natural biopolymer…”
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Mechanical, compositional and morphological characterisation of the human male urethra for the development of a biomimetic tissue engineered urethral scaffold
Published in Biomaterials (01-02-2021)“…This study addresses a crucial gap in the literature by characterising the relationship between urethral tissue mechanics, composition and gross structure. We…”
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Extracellular Vesicles Enhance the Remodeling of Cell-Free Silk Vascular Scaffolds in Rat Aortae
Published in ACS applied materials & interfaces (17-06-2020)“…Vascular tissue engineering is aimed at developing regenerative vascular grafts to restore tissue function by bypassing or replacing defective arterial…”
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CCL2 loaded microparticles promote acute patency in silk-based vascular grafts implanted in rat aortae
Published in Acta biomaterialia (01-11-2021)“…Cardiovascular disease is the leading cause of death worldwide, often associated with coronary artery occlusion. A common intervention for arterial blockage…”
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An exploratory study on the preparation and evaluation of a “same-day” adipose stem cell–based tissue-engineered vascular graft
Published in The Journal of thoracic and cardiovascular surgery (01-11-2018)“…Tissue-engineered vascular grafts containing adipose-derived mesenchymal stem cells offer an alternative to small-diameter vascular grafts currently used in…”
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An Exploratory Study into the Preparation and Evaluation of a “Same-Day” Adipose Stem Cell-Based TEVG
Published in The Journal of thoracic and cardiovascular surgery (02-07-2018)Get full text
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