Search Results - "Lorence, A"
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Design of experiments to evaluate pH and temperature parameters with different inoculums in domestic biodigester
Published in Heliyon (15-05-2024)“…The comprehensive management of organic urban solid waste is a concern due to its direct and indirect impact on the environment. Anaerobic Digestion (AD) has…”
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Vibrio core group induces yellow band disease in Caribbean and Indo-Pacific reef-building corals
Published in Journal of applied microbiology (01-11-2008)“…To determine the relationship between yellow band disease (YBD)-associated pathogenic bacteria found in both Caribbean and Indo-Pacific reefs, and the…”
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3
Camptothecin and 10-hydroxycamptothecin from Camptotheca acuminata hairy roots
Published in Plant cell reports (01-01-2004)“…Camptothecin (CPT) is an anticancer and antiviral alkaloid produced by the Chinese tree Camptotheca acuminata (Nyssaceae) and some other species belonging to…”
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Rituximab Therapy for Refractory Thrombotic Thrombocytopenic Purpura
Published in Blood cells, molecules, & diseases (01-05-2002)“…ABSTRACT While most patients of thrombotic thrombocytopenic purpura (TTP) respond to plasma exchange and achieve remission, a subset of the patients experience…”
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Screening of a broad range of rice (Oryza sativa L.) germplasm for in vitro rapid plant regeneration and development of an early prediction system
Published in In vitro cellular & developmental biology. Plant (01-07-2009)“…Rice has emerged as a model monocot for studies in agriculture and biotechnology due to its relatively small genome and a ready accessibility to plant…”
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Camptothecin, over four decades of surprising findings
Published in Phytochemistry (Oxford) (01-10-2004)“…Here we describe the distribution of camptothecin (CPT) and its metabolites, the present understanding of its mechanism of action, the biosynthetic route…”
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myo-Inositol Oxygenase Offers a Possible Entry Point into Plant Ascorbate Biosynthesis
Published in Plant physiology (Bethesda) (01-03-2004)“…Two biosynthetic pathways for ascorbate (L-ascorbic acid [AsA]; vitamin C) in plants are presently known, the mannose/L-galactose pathway and an L-GalUA…”
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Expression of α-DIOXYGENASE 1 in Tomato and Arabidopsis Contributes to Plant Defenses Against Aphids
Published in Molecular plant-microbe interactions (01-08-2013)“…Plant α-dioxygenases (α-DOX) are fatty acid-hydroperoxidases that contribute to the synthesis of oxylipins, a diverse group of compounds primarily generated…”
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European regulation on orphan medicinal products: 10 years of experience and future perspectives
Published in Nature reviews. Drug discovery (01-05-2011)“…Regulation on orphan medicinal products was adopted in the European Union in 2000, with the aim of benefiting patients who suffer from serious, rare conditions…”
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Treatment of Thrombotic Thrombocytopenic Purpura With Vincristine
Published in JAMA : the journal of the American Medical Association (12-03-1982)“…Five patients with thrombotic thrombocytopenic purpura (TTP) were treated with vincristine sulfate with reversal of all clinical and hematologic evidence of…”
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L-Gulono-1,4-lactone oxidase expression rescues vitamin C-deficient Arabidopsis (vtc) mutants
Published in Plant molecular biology (01-12-2003)“…Vitamin C (L-ascorbic acid) has important antioxidant and metabolic functions in both plants and animals, humans have lost the ability to synthesize it. Fresh…”
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Aminopeptidase dependent pore formation of Bacillus thuringiensis Cry1Ac toxin on Trichoplusia ni membranes
Published in FEBS letters (08-09-1997)“…The insecticidal Bacillus thuringiensis Cry1Ac delta-endotoxin specifically binds to a 120 kDa aminopeptidase N (APN) in the midgut of susceptible insects such…”
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FoxM1: A New Therapeutic Target for Mantle Cell Lymphoma
Published in Blood (08-12-2017)“…Introduction Mantle cell lymphoma (MCL) is an aggressive B-cell lymphoma subtype with elevated B-cell receptor activity. Ibrutinib (IBN), the Bruton's tyrosine…”
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Resistance Mechanisms Underlying Venetoclax Resistance in Mantle Cell Lymphoma
Published in Blood (08-12-2017)“…Background: BCL-2 is highly expressed in mantle cell lymphoma (MCL), and targeting BCL-2 with venetoclax (ABT-199) has resulted in positive clinical outcomes…”
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Targeting the Paracaspase MALT1: A Potential Therapy to Overcome Ibrutinib Resistance in Relapsed/Refractory Mantle Cell Lymphoma Patients
Published in Blood (08-12-2017)“…Mantle cell lymphoma (MCL) is an aggressive B cell malignancy that is not yet curable. Ibrutinib was approved in 2013 for the treatment of relapsed/refractory…”
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Molecular Pathways Associated with Ibrutinib Resistance in Mantle Cell Lymphoma
Published in Blood (08-12-2017)“…Mantle cell lymphoma (MCL) is an aggressive and incurable subtype of B-cell lymphoma and constitutive activation of the B-cell receptor pathway is a hallmark…”
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δ-Endotoxins induce cation channels in Spodoptera frugiperda brush border membranes in suspension and in planar lipid bilayers
Published in FEBS letters (06-03-1995)“…Membrane potential measurements using a fluorescent dye indicated that two specific toxins active against Spodoptera frugiperda larvae (CryIC and CryID) cause…”
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Pre-Clinical Evaluation of the PI3K-p110β/δ Inhibitor KA2237 in Mantle Cell Lymphoma
Published in Blood (02-12-2016)“…Background: Mantle cell lymphoma (MCL) accounts for 6% of all non-Hodgkin lymphoma and is a therapeutic challenge. Phosphoinositide-3 kinase (PI3K) has been…”
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Evidence for intermolecular interaction as a necessary step for pore-formation activity and toxicity of Bacillus thuringiensis Cry1Ab toxin
Published in FEMS microbiology letters (15-10-2000)“…Based on the observation of large conductance states formed by Bacillus thuringiensis Cry toxins in synthetic planar lipid bilayers and the estimation of a…”
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Thrombotic thrombocytopenic purpura
Published in Archives of internal medicine (1960) (01-04-1984)Get more information
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