Search Results - "Lorena Martin-Jaular"

Unbiased proteomic profiling of host cell extracellular vesicle composition and dynamics upon HIV‐1 infection by Martin‐Jaular, Lorena, Nevo, Nathalie, Schessner, Julia P, Tkach, Mercedes, Jouve, Mabel, Dingli, Florent, Loew, Damarys, Witwer, Kenneth W, Ostrowski, Matias, Borner, Georg H H, Théry, Clotilde

“…Cells release diverse types of extracellular vesicles (EVs), which transfer complex signals to surrounding cells. Specific markers to distinguish different EVs…”
Get full text

Extracellular vesicles containing ACE2 efficiently prevent infection by SARS‐CoV‐2 Spike protein‐containing virus by Cocozza, Federico, Névo, Nathalie, Piovesana, Ester, Lahaye, Xavier, Buchrieser, Julian, Schwartz, Olivier, Manel, Nicolas, Tkach, Mercedes, Théry, Clotilde, Martin‐Jaular, Lorena

“…SARS‐CoV‐2 entry is mediated by binding of the spike protein (S) to the surface receptor ACE2 and subsequent priming by host TMPRSS2 allowing membrane fusion…”
Get full text

Extracellular vesicles and co‐isolated endogenous retroviruses from murine cancer cells differentially affect dendritic cells by Cocozza, Federico, Martin‐Jaular, Lorena, Lippens, Lien, Di Cicco, Aurelie, Arribas, Yago A, Ansart, Nicolas, Dingli, Florent, Richard, Michael, Merle, Louise, Jouve San Roman, Mabel, Poullet, Patrick, Loew, Damarys, Lévy, Daniel, Hendrix, An, Kassiotis, George, Joliot, Alain, Tkach, Mercedes, Théry, Clotilde

“…Cells secrete extracellular vesicles (EVs) and non‐vesicular extracellular (nano)particles (NVEPs or ENPs) that may play a role in intercellular communication…”
Get full text

Extracellular vesicles in parasitic diseases by Marcilla, Antonio, Martin-Jaular, Lorena, Trelis, Maria, de Menezes-Neto, Armando, Osuna, Antonio, Bernal, Dolores, Fernandez-Becerra, Carmen, Almeida, Igor C., del Portillo, Hernando A.

“…Parasitic diseases affect billions of people and are considered a major public health issue. Close to 400 species are estimated to parasitize humans, of which…”
Get full text

Extracellular vesicles and chronic inflammation during HIV infection by Pérez, Paula Soledad, Romaniuk, María Albertina, Duette, Gabriel A., Zhao, Zezhou, Huang, Yiyao, Martin-Jaular, Lorena, Witwer, Kenneth W, Théry, Clotilde, Ostrowski, Matías

“…Inflammation is a hallmark of HIV infection. Among the multiple stimuli that can induce inflammation in untreated infection, ongoing viral replication is a…”
Get full text

Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication by Mathieu, Mathilde, Martin-Jaular, Lorena, Lavieu, Grégory, Théry, Clotilde

“…The ability of exosomes to transfer cargo from donor to acceptor cells, thereby triggering phenotypic changes in the latter, has generated substantial interest…”
Get full text

Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals by de Menezes-Neto, Armando, Sáez, María José Fidalgo, Lozano-Ramos, Inés, Segui-Barber, Joan, Martin-Jaular, Lorena, Ullate, Josep M. Estanyol, Fernandez-Becerra, Carmen, Borrás, Francesc E., del Portillo, Hernando A.

“…Plasma-derived vesicles hold a promising potential for use in biomedical applications. Two major challenges, however, hinder their implementation into…”
Get full text

Urinary extracellular vesicles contain mature transcriptome enriched in circular and long noncoding RNAs with functional significance in prostate cancer by Almeida, Anna, Gabriel, Marc, Firlej, Virginie, Martin‐Jaular, Lorena, Lejars, Matthieu, Cipolla, Rocco, Petit, Floriane, Vogt, Nicolas, San‐Roman, Mabel, Dingli, Florent, Loew, Damarys, Destouches, Damien, Vacherot, Francis, de la Taille, Alexandre, Théry, Clotilde, Morillon, Antonin

“…Long noncoding (lnc)RNAs modulate gene expression alongside presenting unexpected source of neoantigens. Despite their immense interest, their ability to be…”
Get full text

Homosalate boosts the release of tumour‐derived extracellular vesicles with protection against anchorage‐loss property by Grisard, Eleonora, Nevo, Nathalie, Lescure, Aurianne, Doll, Sebastian, Corbé, Maxime, Jouve, Mabel, Lavieu, Gregory, Joliot, Alain, Nery, Elaine Del, Martin‐Jaular, Lorena, Théry, Clotilde

“…Eukaryotic cells, including cancer cells, secrete highly heterogeneous populations of extracellular vesicles (EVs). EVs could have different subcellular…”
Get full text

Qualitative differences in T‐cell activation by dendritic cell‐derived extracellular vesicle subtypes by Tkach, Mercedes, Kowal, Joanna, Zucchetti, Andres E, Enserink, Lotte, Jouve, Mabel, Lankar, Danielle, Saitakis, Michael, Martin‐Jaular, Lorena, Théry, Clotilde

“…Exosomes, nano‐sized secreted extracellular vesicles (EVs), are actively studied for their diagnostic and therapeutic potential. In particular, exosomes…”
Get full text

Cell culture-derived extracellular vesicles: Considerations for reporting cell culturing parameters by Shekari, Faezeh, Alibhai, Faisal J, Baharvand, Hossein, Börger, Verena, Bruno, Stefania, Davies, Owen, Giebel, Bernd, Gimona, Mario, Salekdeh, Ghasem Hosseini, Martin-Jaular, Lorena, Mathivanan, Suresh, Nelissen, Inge, Nolte-'t Hoen, Esther, O'Driscoll, Lorraine, Perut, Francesca, Pluchino, Stefano, Pocsfalvi, Gabriella, Salomon, Carlos, Soekmadji, Carolina, Staubach, Simon, Torrecilhas, Ana Claudia, Shelke, Ganesh Vilas, Tertel, Tobias, Zhu, Dandan, Théry, Clotilde, Witwer, Kenneth, Nieuwland, Rienk

“…Cell culture-conditioned medium (CCM) is a valuable source of extracellular vesicles (EVs) for basic scientific, therapeutic and diagnostic applications. Cell…”
Get full text

The role of the spleen in malaria by del Portillo, Hernando A., Ferrer, Mireia, Brugat, Thibaut, Martin‐Jaular, Lorena, Langhorne, Jean, Lacerda, Marcus V. G.

“…Summary The spleen is a complex organ that is perfectly adapted to selectively filtering and destroying senescent red blood cells (RBCs), infectious…”
Get full text

The Role of Extracellular Vesicles in Modulating the Host Immune Response during Parasitic Infections by Montaner, Sergio, Galiano, Alicia, Trelis, María, Martin-Jaular, Lorena, Del Portillo, Hernando A, Bernal, Dolores, Marcilla, Antonio

“…Parasites are the cause of major diseases affecting billions of people. As the inflictions caused by these parasites affect mainly developing countries, they…”
Get full text

Detection of the interactions of tumour derived extracellular vesicles with immune cells is dependent on EV‐labelling methods by Loconte, Luisa, Arguedas, Davinia, El, Rojbin, Zhou, Alix, Chipont, Anna, Guyonnet, Lea, Guerin, Coralie, Piovesana, Ester, Vázquez‐Ibar, José Luis, Joliot, Alain, Théry, Clotilde, Martín‐Jaular, Lorena

“…Cell‐cell communication within the complex tumour microenvironment is critical to cancer progression. Tumor‐derived extracellular vesicles (TD‐EVs) are key…”
Get full text

Acetylcholinesterase is not a generic marker of extracellular vesicles by Liao, Zhaohao, Jaular, Lorena Martin, Soueidi, Estelle, Jouve, Mabel, Muth, Dillon C., Schøyen, Tine H., Seale, Tessa, Haughey, Norman J., Ostrowski, Matias, Théry, Clotilde, Witwer, Kenneth W.

“…Acetylcholinesterase (AChE) activity is found in abundance in reticulocytes and neurons and was developed as a marker of reticulocyte EVs in the 1970s. Easily,…”
Get full text

Spleen rupture in a case of untreated Plasmodium vivax infection by Machado Siqueira, André, Lopes Magalhães, Belisa Maria, Cardoso Melo, Gisely, Ferrer, Mireia, Castillo, Paola, Martin-Jaular, Lorena, Fernandez-Becerra, Carmen, Ordi, Jaume, Martinez, Antonio, Lacerda, Marcus Vinícius Guimarães, del Portillo, Hernando A

Get full text

Exosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections by Martin-Jaular, Lorena, Nakayasu, Ernesto S, Ferrer, Mireia, Almeida, Igor C, Del Portillo, Hernando A

“…Exosomes are 30-100-nm membrane vesicles of endocytic origin that are released after the fusion of multivesicular bodies (MVBs) with the plasma membrane. While…”
Get full text

International Society for Extracellular Vesicles workshop. QuantitatEVs: Multiscale analyses, from bulk to single extracellular vesicle by Basso, Manuela, Gori, Alessandro, Nardella, Caterina, Palviainen, Mari, Holcar, Marija, Sotiropoulos, Ioannis, Bobis‐Wozowicz, Sylwia, D'Agostino, Vito G., Casarotto, Elena, Ciani, Yari, Suetsugu, Shiro, Gualerzi, Alice, Martin‐Jaular, Lorena, Boselli, Daniela, Kashkanova, Anna, Parisse, Pietro, Lippens, Lien, Pagliuca, Martina, Blessing, Martin, Frigerio, Roberto, Fourniols, Thibaut, Meliciano, Ana, Fietta, Anna, Fioretti, Paolo Vincenzo, Soroczyńska, Karolina, Picciolini, Silvia, Salviano‐Silva, Amanda, Bergese, Paolo, Zocco, Davide, Chiari, Marcella, Jenster, Guido, Waldron, Levi, Milosavljevic, Aleksandar, Nolan, John, Monopoli, Marco P., Witwer, Kenneth W., Bussolati, Benedetta, Di Vizio, Dolores, Falcon Perez, Juan, Lenassi, Metka, Cretich, Marina, Demichelis, Francesca

“…The “QuantitatEVs: multiscale analyses, from bulk to single vesicle” workshop aimed to discuss quantitative strategies and harmonized wet and computational…”
Get full text

Strain‐specific spleen remodelling in Plasmodium yoelii infections in Balb/c mice facilitates adherence and spleen macrophage‐clearance escape by Martin‐Jaular, Lorena, Ferrer, Mireia, Calvo, Maria, Rosanas‐Urgell, Anna, Kalko, Susana, Graewe, Stefanie, Soria, Guadalupe, Cortadellas, Núria, Ordi, Jaume, Planas, Anna, Burns, James, Heussler, Volker, del Portillo, Hernando A.

“…Summary Knowledge of the dynamic features of the processes driven by malaria parasites in the spleen is lacking. To gain insight into the function and…”
Get full text

On cytoadhesion of Plasmodium vivax: raison d'être? by Costa, Fabio T M, Lopes, Stefanie C P, Ferrer, Mireia, Leite, Juliana A, Martin-Jaular, Lorena, Bernabeu, Maria, Nogueira, Paulo A, Mourão, Maria Paula G, Fernandez-Becerra, Carmen, Lacerda, Marcus V G, del Portillo, Hernando

“…It is generally accepted that Plasmodium vivax, the most widely distributed human malaria parasite, causes mild disease and that this species does not…”
Get full text