Search Results - "Lord, Kevin"

Neurological Complications of COVID-19: Underlying Mechanisms and Management by Shehata, Ghaydaa A, Lord, Kevin C, Grudzinski, Michaela C, Elsayed, Mohamed, Abdelnaby, Ramy, Elshabrawy, Hatem A

“…COVID-19 is a severe respiratory disease caused by the newly identified human coronavirus (HCoV) Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)…”
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Cardiac fibroblast-dependent extracellular matrix accumulation is associated with diastolic stiffness in type 2 diabetes by Hutchinson, Kirk R, Lord, C Kevin, West, T Aaron, Stewart, Jr, James A

“…Cardiovascular complications are a leading cause of death in patients with type 2 diabetes mellitus (T2DM). Diastolic dysfunction is one of the earliest…”
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A Process Map of NGS for FIGG by Walker, Sara, Lord, Kevin

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Mesenteric resistance arteries in type 2 diabetic db/db mice undergo outward remodeling by Souza-Smith, Flavia M, Katz, Paige S, Trask, Aaron J, Stewart, Jr, James A, Lord, Kevin C, Varner, Kurt J, Vassallo, Dalton V, Lucchesi, Pamela A

“…Resistance vessel remodeling is controlled by myriad of hemodynamic and neurohormonal factors. This study characterized structural and molecular remodeling in…”
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Temporal pattern of left ventricular structural and functional remodeling following reversal of volume overload heart failure by HUTCHINSON, Kirk R, GUGGILAM, Anuradha, CISMOWSKI, Mary J, GALANTOWICZ, Maarten L, WEST, Thomas A, STEWART, James A, XIAOJIN ZHANG, LORD, Kevin C, LUCCHESI, Pamela A

“…Current surgical management of volume overload-induced heart failure (HF) leads to variable recovery of left ventricular (LV) function despite a return of LV…”
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Oxidative stress contributes to methamphetamine-induced left ventricular dysfunction by Lord, Kevin C., Shenouda, Sylvia K., McIlwain, Elizabeth, Charalampidis, Dimitrios, Lucchesi, Pamela A., Varner, Kurt J.

“…Aims Our aim was to test the hypothesis that the repeated, binge administration of methamphetamine would produce oxidative stress in the myocardium leading to…”
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Coronary arterioles in type 2 diabetic (db/db) mice undergo a distinct pattern of remodeling associated with decreased vessel stiffness by Katz, Paige S., Trask, Aaron J., Souza-Smith, Flavia M., Hutchinson, Kirk R., Galantowicz, Maarten L., Lord, Kevin C., Stewart, James A., Cismowski, Mary J., Varner, Kurt J., Lucchesi, Pamela A.

“…Little is known about the impact of type 2 diabetes mellitus (DM) on coronary arteriole remodeling. The aim of this study was to determine the mechanisms that…”
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Activator of G Protein Signaling 3 Null Mice: I. Unexpected Alterations in Metabolic and Cardiovascular Function by Blumer, Joe B, Lord, Kevin, Saunders, Thomas L, Pacchioni, Alejandra, Black, Cory, Lazartigues, Eric, Varner, Kurt J, Gettys, Thomas W, Lanier, Stephen M

“…Activator of G protein signaling (AGS)-3 plays functional roles in cell division, synaptic plasticity, addictive behavior, and neuronal development. As part of…”
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Electronic tongue for pharmaceutical analytics: quantification of tastes and masking effects by Legin, Andrey, Rudnitskaya, Alisa, Clapham, David, Seleznev, Boris, Lord, Kevin, Vlasov, Yuri

“…The organoleptic aspects of pharmaceutical formulations affect their acceptability to the patient and hence can have an important effect on concordance with…”
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Effects of PARP-1 deficiency on airway inflammatory cell recruitment in response to LPS or TNF: differential effects on CXCR2 ligands and Duffy antigen receptor for chemokines by Zerfaoui, Mourad, Naura, Amarjit S., Errami, Youssef, Hans, Chetan P., Rezk, Bashir M., Park, Jiwon, Elsegeiny, Waleed, Kim, Hogyoung, Lord, Kevin, Kim, Jong G., Boulares, A. Hamid

“…Differential influences mediated by PARP‐1 on the balance of pro‐neutrophilic or pro‐macrophagic stimulatory factors may govern the nature of airway…”
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Ecstasy produces left ventricular dysfunction and oxidative stress in rats by Shenouda, Sylvia K., Lord, Kevin C., McIlwain, Elizabeth, Lucchesi, Pamela A., Varner, Kurt J.

“…Aims Our aim was to determine whether the repeated, binge administration of 3,4-methylenedioxymethamphetamine (ecstasy; MDMA) produces structural and/or…”
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Developing Effective Study Groups in the Quest for the “Holy Grail”: Critical Thinking by Linn, William D., Lord, Kevin C., Whong, Christine Y., Phillips, Eli G.

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Changes in cardiovascular responsiveness and cardiotoxicity elicited during binge administration of Ecstasy by Badon, Lisa A, Hicks, Alissa, Lord, Kevin, Ogden, Brian A, Meleg-Smith, Suzanne, Varner, Kurt J

“…The recreational use of 3,4-methylenedioxymethamphetamine (MDMA; Ecstasy) is often characterized by a repeated pattern of frequent drug administrations (binge)…”
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Reports of the demise of chemotherapy have been greatly exaggerated by Feinberg, Bruce, Kish, Jonathan, Dokubo, Igoni, Wojtynek, Jeff, Lord, Kevin

“…Does the rapid integration of both targeted and immuno-oncology drugs into treatment guidelines across solid tumors and hematologic malignancies herald the…”
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Comparative Effectiveness of Palliative Chemotherapy in Metastatic Breast Cancer: A Real‐World Evidence Analysis by Feinberg, Bruce, Kish, Jonathan, Dokubo, Igoni, Wojtynek, Jeff, Gajra, Ajeet, Lord, Kevin

“…Background In the absence of randomized controlled trials, real‐world evidence may aid practitioners in optimizing the selection of therapy for patients with…”
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Real-World Dosing Patterns of Ruxolitinib in Patients with Polycythemia Vera Who Are Resistant to or Intolerant of Hydroxyurea by Altomare, Ivy, Nguyen, Anna, Parasuraman, Shreekant, Paranagama, Dilan, Kish, Jonathan K., Lord, Kevin, Colucci, Philomena

“…Background Polycythemia vera (PV) is a myeloproliferative neoplasm affecting >100,000 people in the United States annually. Patients (pts) with PV are at risk…”
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Real-World Dosing Patterns of Ruxolitinib in Patients With Polycythemia Vera Who Are Resistant to or Intolerant of Hydroxyurea by Altomare, Ivy, Parasuraman, Shreekant, Paranagama, Dilan, Kish, Jonathan, Lord, Kevin, Yu, Jingbo, Colucci, Philomena

“…•About 1 in 4 patients with polycythemia vera become resistant and/or intolerant to hydroxyurea.•Ruxolitinib is the only FDA-approved polycythemia vera…”
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Real-world evidence evaluating the use of single versus combination chemotherapy in salvage therapy for metastatic breast cancer by Feinberg, Bruce A., Lord, Kevin, Kish, Jonathan, Laney, Jalyna R., Chopra, Dhruv, Liassou, Djibril

“…Abstract only e12600 Background: Metastatic breast cancer (mBC) patients often receive multiple lines of systemic chemotherapy (Chemo) to extend life, manage…”
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Real-world evidence evaluating the use of an NK-1 antiemetic in the systemic chemotherapy treatment of metastatic breast cancer by Lord, Kevin, Feinberg, Bruce A., Kish, Jonathan, Laney, Jalyna R., Chopra, Dhruv, Liassou, Djibril

“…Abstract only e12599 Background: Severe and persistent nausea and vomiting (n/v) impacts quality of life and may lead to treatment discontinuation. While…”
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Use of a granulocyte colony-stimulating factor for the prevention of febrile neutropenia in the era of value-based care by Feinberg, Bruce A., Lord, Kevin, Kish, Jonathan, Laney, Jalyna R., Chopra, Dhruv, Liassou, Djibril

“…Abstract only e12601 Background: Value based care design is intended to encourage responsible use of medical resources to optimize cost effective delivery of…”
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