Search Results - "Lord, Kenneth A."
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1
mDYRK3 kinase is expressed selectively in late erythroid progenitor cells and attenuates colony-forming unit-erythroid development
Published in Blood (15-02-2001)“…DYRKs are a new subfamily of dual-specificity kinases that was originally discovered on the basis of homology to Yak1, an inhibitor of cell cycle progression…”
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2
New benzimidazoles as thrombopoietin receptor agonists
Published in Bioorganic & medicinal chemistry letters (01-03-2006)“…The synthesis and SAR of a novel, rationally designed series of benzimidazole TPO receptor agonists are reported. A novel benzimidazole series of…”
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3
REDK, a novel human regulatory erythroid kinase
Published in Blood (01-05-2000)“…We have identified a novel regulatory erythroid kinase (REDK) that is homologous to a family of dual-specificity kinases. The yeast homolog of REDK negatively…”
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4
SUBTRACTION CLONING AND INITIAL CHARACTERIZATION OF NOVEL EPO-IMMEDIATE RESPONSE GENES
Published in Cytokine (Philadelphia, Pa.) (01-07-2000)“…Recent studies of erythropoietin (Epo) receptor signalling suggest that signals for mitogenesis, survival and differentiation are relayed efficiently by…”
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5
Interleukin-6 and Leukemia Inhibitory Factor Induction of JunB Is Regulated by Distinct Cell Type-specific Cis-acting Elements
Published in The Journal of biological chemistry (01-10-1999)“…Interleukin (IL)-6 plays an important role in a wide range of biological activities, including differentiation of murine M1 myeloid leukemic cells into mature…”
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6
Sequence of MyD116 cDNA : a novel myeloid differentiation primary response gene induced by IL6
Published in Nucleic acids research (11-05-1990)Get full text
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7
Vanadyl(IV)-thallium(I)-205,203 superhyperfine coupling in complexes with pyruvate kinase
Published in Inorganic chemistry (01-05-1987)Get full text
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8
The gadd and MyD genes define a novel set of mammalian genes encoding acidic proteins that synergistically suppress cell growth
Published in Molecular and Cellular Biology (01-04-1994)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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9
Nucleotide sequence and expression of a cDNA encoding MyD88, a novel myeloid differentiation primary response gene induced by IL6
Published in Oncogene (01-07-1990)“…We report here the full length cDNA sequence and the deduced amino-acid sequence of MyD88, a novel myeloid differentiation primary response gene activated in…”
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10
Proto-oncogenes of the fos/jun family of transcription factors are positive regulators of myeloid differentiation
Published in Molecular and Cellular Biology (01-02-1993)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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11
Signaling Induced by Erythropoietin and Stem Cell Factor in UT‐7/Epo Cells: Transient versus Sustained Proliferation
Published in Stem cells (Dayton, Ohio) (01-01-2000)“…UT‐7/Epo cells are human factor‐dependent erythroleukemic cells, requiring erythropoietin (Epo) for long‐term growth. Stem cell factor (SCF) stimulates…”
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12
Leukemia inhibitory factor and interleukin-6 trigger the same immediate early response, including tyrosine phosphorylation, upon induction of myeloid leukemia differentiation
Published in Molecular and Cellular Biology (01-09-1991)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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13
Sequence and expression of a cDNA encoding MyD118: a novel myeloid differentiation primary response gene induced by multiple cytokines
Published in Oncogene (01-01-1991)“…We report here the full length cDNA sequence and the deduced amino acid sequence of MyD118, a novel myeloid differentiation primary response gene transiently…”
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14
Complexity of the immediate early response of myeloid cells to terminal differentiation and growth arrest includes ICAM-1, Jun-B and histone variants
Published in Oncogene (01-03-1990)“…Differentiation inducible leukemic as well as normal myeloid precursors treated with physiological myeloid differentiation inducer have been used to explore…”
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15
Variant cDNA Sequences of Human ATP:Citrate Lyase: Cloning, Expression, and Purification from Baculovirus-Infected Insect Cells
Published in Protein expression and purification (01-02-1997)“…ATP:citrate lyase (ACL) is a major generator of cytosolic acetyl-coenzymeA, which is required for both fatty acid and cholesterol biosynthesis. The human ACL…”
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16
Vanadyl(IV) complexes with pyruvate kinase: activation of the enzyme and electron paramagnetic resonance properties of ternary complexes with the protein
Published in Archives of biochemistry and biophysics (15-08-1990)“…Complexes of the oxocation of vanadyl(IV), VO2+, with pyruvate kinase from rabbit muscle have been investigated by steady-state kinetic assays and by EPR…”
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17
Proto-Oncogenes of the fos/jun Family of Transcription Factors are Positive Regulators of Myeloid Differentiation
Published in Molecular and cellular biology (01-02-1993)“…The proto-oncogenes c-jun, junB, junD, and c-fos recently have been shown to encode for transcription factors with a leucine zipper that mediates dimerization…”
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18
The gadd and MyD Genes Define a Novel Set of Mammalian Genes Encoding Acidic Proteins That Synergistically Suppress Cell Growth
Published in Molecular and cellular biology (01-04-1994)“…A remarkable overlap was observed between the gadd genes, a group of often coordinately expressed genes that are induced by genotoxic stress and certain other…”
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19
Leukemia Inhibitory Factor and Interleukin-6 Trigger the Same Immediate Early Response, Including Tyrosine Phosphorylation, upon Induction of Myeloid Leukemia Differentiation
Published in Molecular and cellular biology (01-09-1991)“…Leukemia inhibitory factor (LIF) and interleukin-6 (IL-6), two multifunctional cytokines lacking structural homology and binding to distinct receptors, share…”
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