Search Results - "Lora, Maximilien"

Human multipotent mesenchymal stromal cells cytokine priming promotes RAB27B-regulated secretion of small extracellular vesicles with immunomodulatory cargo by Cheng, Anastasia, Choi, Dongsic, Lora, Maximilien, Shum-Tim, Dominique, Rak, Janusz, Colmegna, Inés

“…The paracrine effects of multipotent mesenchymal stromal cells (MSCs) are mediated by their secretome composed by soluble factors (i.e., cytokines, growth…”
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Mitochondrial Oxidative Stress Reduces the Immunopotency of Mesenchymal Stromal Cells in Adults With Coronary Artery Disease by Kizilay Mancini, Ozge, Lora, Maximilien, Cuillerier, Alexanne, Shum-Tim, Dominique, Hamdy, Reggie, Burelle, Yan, Servant, Marc J, Stochaj, Ursula, Colmegna, Inés

“…RATIONALE:Mesenchymal stromal cells (MSCs) are promising therapeutic strategies for coronary artery disease; however, donor-related variability in cell quality…”
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CD26 is a senescence marker associated with reduced immunopotency of human adipose tissue-derived multipotent mesenchymal stromal cells by Psaroudis, Rose Triantafillia, Singh, Urvashi, Lora, Maximilien, Jeon, Peter, Boursiquot, Abigail, Stochaj, Ursula, Langlais, David, Colmegna, Inés

“…Abstract Introduction Human mesenchymal stromal cells (MSCs) have immunomodulatory, anti-inflammatory, and tolerogenic effects. Long-term in vitro expansion of…”
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A Proinflammatory Secretome Mediates the Impaired Immunopotency of Human Mesenchymal Stromal Cells in Elderly Patients with Atherosclerosis by Kizilay Mancini, Özge, Lora, Maximilien, Shum‐Tim, Dominique, Nadeau, Stephanie, Rodier, Francis, Colmegna, Inés

“…Inflammation plays a pivotal role in the initiation and progression of atherosclerosis (ATH). Due to their potent immunomodulatory properties, mesenchymal…”
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Characterization and use of the ECV304 autoantigenic citrullinome to understand anti-citrullinated protein/peptide autoantibodies in rheumatoid arthritis by de França, Natalia Regine, Ménard, Henri André, Lora, Maximilien, Zhou, Zhijie, Rauch, Joyce, Hitchon, Carol, Andrade, Luís Eduardo Coelho, Colmegna, Inés

“…Anti-citrullinated protein antibodies (ACPAs) are highly specific for rheumatoid arthritis (RA). In vivo, ACPAs target peptidyl-citrulline epitopes (cit-) in a…”
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Cytokine priming enhances the antifibrotic effects of human adipose derived mesenchymal stromal cells conditioned medium by Brizio, Marianela, Mancini, Mathieu, Lora, Maximilien, Joy, Sydney, Zhu, Shirley, Brilland, Benoit, Reinhardt, Dieter P, Farge, Dominique, Langlais, David, Colmegna, Inés

“…Fibrosis is a pathological scarring process characterized by persistent myofibroblast activation with excessive accumulation of extracellular matrix (ECM)…”
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Whole-genome bisulfite sequencing in systemic sclerosis provides novel targets to understand disease pathogenesis by Lu, Tianyuan, Klein, Kathleen Oros, Colmegna, Inés, Lora, Maximilien, Greenwood, Celia M T, Hudson, Marie

“…Systemic sclerosis (SSc) is a rare autoimmune connective tissue disease whose pathogenesis remains incompletely understood. Increasing evidence suggests that…”
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Novel insights into systemic sclerosis using a sensitive computational method to analyze whole-genome bisulfite sequencing data by Yu, Jeffrey C Y, Zeng, Yixiao, Zhao, Kaiqiong, Lu, Tianyuan, Oros Klein, Kathleen, Colmegna, Inés, Lora, Maximilien, Bhatnagar, Sahir R, Leask, Andrew, Greenwood, Celia M T, Hudson, Marie

“…Abnormal DNA methylation is thought to contribute to the onset and progression of systemic sclerosis. Currently, the most comprehensive assay for profiling DNA…”
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Novel insights into systemic autoimmune rheumatic diseases using shared molecular signatures and an integrative analysis by Hudson, Marie, Bernatsky, Sasha, Colmegna, Ines, Lora, Maximilien, Pastinen, Tomi, Klein Oros, Kathleen, Greenwood, Celia M T

“…We undertook this study to identify DNA methylation signatures of three systemic autoimmune rheumatic diseases (SARDs), namely rheumatoid arthritis, systemic…”
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Anti-cyclic citrullinated peptide antibodies are a collection of anti-citrullinated protein antibodies and contain overlapping and non-overlapping reactivities by Ioan-Facsinay, Andreea, el-Bannoudi, Hanane, Scherer, Hans U, van der Woude, Diane, Ménard, Henri A, Lora, Maximilien, Trouw, Leendert A, Huizinga, Tom W J, Toes, Rene E M

“…Anti-citrullinated protein antibodies (ACPA) and anti-cyclic citrullinated peptide (anti-CCP) antibodies are a hallmark of rheumatoid arthritis and are…”
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Induction of cyclooxygenase-2 by parathyroid hormone in human osteoblasts in culture by Maciel, F M, Sarrazin, P, Morisset, S, Lora, M, Patry, C, Dumais, R, de Brum-Fernandes, A J

“…Parathyroid hormone (PTH) induced bone resorption by osteoclasts depends on the presence of osteoblasts. PTH induced production of prostaglandins by…”
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Implication des récepteurs aux prostaglandines et des isoenzymes de la cyclooxygénase dans l'ostéoclastogénèse humaine by Lora, Maximilien

“…Les prostaglandines affectent la différentiation et l'activité des ostéoclastes in vivo et in vitro comme il a été démontré dans plusieurs modèles animaux. Par…”
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Expression of prostaglandin endoperoxide synthase-1 and prostaglandin endoperoxide synthase-2 in human osteoblasts by de Brum-Fernandes, A J, Laporte, S, Heroux, M, Lora, M, Patry, C, Ménard, H A, Dumais, R, Leduc, R

“…A Prostaglandin endoperoxide synthase isoenzyme was recently identified in several cell lines. Osteoblasts possess Prostaglandin endoperoxide synthase…”
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Novel insights into systemic autoimmune rheumatic diseases using shared molecular signatures and an integrative analysis by Hudson, Marie, Bernatsky, Sasha, Colmegna, Ines, Lora, Maximilien, Pastinen, Tomi, Klein Oros, Kathleen, Greenwood, Celia M. T.

“…We undertook this study to identify DNA methylation signatures of three systemic autoimmune rheumatic diseases (SARDs), namely rheumatoid arthritis, systemic…”
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Expression heterologue des isoenzymes de la cyclooxygenase humaine et selectivite d'inhibition par les anti-inflammatoires non steroidiens by Lora, Maximilien

“…Les anti-inflammatoires non steroidiens (AINS) sont couramment utilises dans le traitement des maladies inflammatoires. Ils inhibent la cyclooxygenase (COX),…”
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