Search Results - "Loré, K"

A hexavalent Coxsackievirus B vaccine is highly immunogenic and has a strong protective capacity in mice and nonhuman primates by Stone, V M, Hankaniemi, M M, Laitinen, O H, Sioofy-Khojine, A B, Lin, A, Diaz Lozano, I M, Mazur, M A, Marjomäki, V, Loré, K, Hyöty, H, Hytönen, V P, Flodström-Tullberg, M

“…Coxsackievirus B (CVB) enteroviruses are common human pathogens known to cause severe diseases including myocarditis, chronic dilated cardiomyopathy, and…”
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Prospects for induction of CD8 T cell‐mediated immunity to Zika virus infection by yellow fever virus vaccination by Blom, K., Sandberg, J. T., Loré, K., Ljunggren, H.‐G.

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Delayed generation of functional virus-specific circulating T follicular helper cells correlates with severe COVID-19 by Yu, Meng, Charles, Afandi, Cagigi, Alberto, Christ, Wanda, Österberg, Björn, Falck-Jones, Sara, Azizmohammadi, Lida, Åhlberg, Eric, Falck-Jones, Ryan, Svensson, Julia, Nie, Mu, Warnqvist, Anna, Hellgren, Fredrika, Lenart, Klara, Arcoverde Cerveira, Rodrigo, Ols, Sebastian, Lindgren, Gustaf, Lin, Ang, Maecker, Holden, Bell, Max, Johansson, Niclas, Albert, Jan, Sundling, Christopher, Czarnewski, Paulo, Klingström, Jonas, Färnert, Anna, Loré, Karin, Smed-Sörensen, Anna

“…Effective humoral immune responses require well-orchestrated B and T follicular helper (Tfh) cell interactions. Whether these interactions are impaired and…”
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Monocytes Acquire the Ability to Prime Tissue-Resident T Cells via IL-10-Mediated TGF-β Release by Thompson, Elizabeth A., Darrah, Patricia A., Foulds, Kathryn E., Hoffer, Elena, Caffrey-Carr, Alayna, Norenstedt, Sophie, Perbeck, Leif, Seder, Robert A., Kedl, Ross M., Loré, Karin

“…Using non-human primates (NHPs), mice, and human primary cells, we found a role for interleukin-10 (IL-10) in the upregulation of the tissue-resident memory…”
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Additive effects of booster mRNA vaccination and SARS-CoV-2 Omicron infection on T cell immunity across immunocompromised states by Müller, Thomas R, Sekine, Takuya, Trubach, Darya, Niessl, Julia, Chen, Puran, Bergman, Peter, Blennow, Ola, Hansson, Lotta, Mielke, Stephan, Nowak, Piotr, Vesterbacka, Jan, Akber, Mira, Olofsson, Anna, Amaya Hernandez, Susana Patricia, Gao, Yu, Cai, Curtis, Söderdahl, Gunnar, Smith, C I Edvard, Österborg, Anders, Loré, Karin, Sällberg Chen, Margaret, Ljungman, Per, Ljunggren, Hans-Gustaf, Karlsson, Annika C, Saini, Sunil Kumar, Aleman, Soo, Buggert, Marcus

“…Suboptimal immunity to SARS-CoV-2 mRNA vaccination has frequently been observed in individuals with various immunodeficiencies. Given the increased antibody…”
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Imatinib inhibits T-cell receptor–mediated T-cell proliferation and activation in a dose-dependent manner by Seggewiss, Ruth, Loré, Karin, Greiner, Elisabeth, Magnusson, Magnus K., Price, David A., Douek, Daniel C., Dunbar, Cynthia E., Wiestner, Adrian

“…The tyrosine kinase inhibitor imatinib (imatinib, STI571, Glivec, and Gleevec) is increasingly used in patients undergoing allogeneic transplantation for…”
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Cellular and humoral response to SARS-CoV-2 vaccine BNT162b2 in adults with Chronic Kidney Disease G4/5 by Rosdahl, Anja, Hellgren, Fredrika, Norén, Torbjörn, Smolander, Jessica, Wopenka, Ursula, Loré, Karin, Hervius Askling, Helena

“…The mRNA vaccines have proven to be very effective in preventing severe disease and death from SARS-CoV-2 in the general population. However, in patients with…”
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HIV Gag Protein Conjugated to a Toll-like Receptor 7/8 Agonist Improves the Magnitude and Quality of Th1 and CD8+T Cell Responses in Nonhuman Primates by Ulrike Wille-Reece, Barbara J. Flynn, Karin Loré, Koup, Richard A., Kedl, Ross M., Mattapallil, Joseph J., Weiss, Walter R., Roederer, Mario, Seder, Robert A.

“…Induction and maintenance of antibody and T cell responses will be critical for developing a successful vaccine against HIV. A rational approach for generating…”
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Toll-like receptor agonists influence the magnitude and quality of memory T cell responses after prime-boost immunization in nonhuman primates by Wille-Reece, Ulrike, Flynn, Barbara J, Loré, Karin, Koup, Richard A, Miles, Aaron P, Saul, Allan, Kedl, Ross M, Mattapallil, Joseph J, Weiss, Walter R, Roederer, Mario, Seder, Robert A

“…There is a remarkable heterogeneity in the functional profile (quality) of T cell responses. Importantly, the magnitude and/or quality of a response required…”
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Myeloid and plasmacytoid dendritic cells transfer HIV-1 preferentially to antigen-specific CD4+ T cells by Loré, Karin, Smed-Sörensen, Anna, Vasudevan, Jayanand, Mascola, John R, Koup, Richard A

“…Dendritic cells (DCs) are essential antigen-presenting cells for the induction of T cell immunity against pathogens such as human immunodeficiency virus…”
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Toll-Like Receptor Ligands Modulate Dendritic Cells to Augment Cytomegalovirus- and HIV-1-Specific T Cell Responses by Lore, Karin, Betts, Michael R, Brenchley, Jason M, Kuruppu, Janaki, Khojasteh, Soorena, Perfetto, Stephen, Roederer, Mario, Seder, Robert A, Koup, Richard A

“…Optimal Ag targeting and activation of APCs, especially dendritic cells (DCs), are important in vaccine development. In this study, we report the effects of…”
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Real-world assessment of immunogenicity in immunocompromised individuals following SARS-CoV-2 mRNA vaccination: a one-year follow-up of the prospective clinical trial COVAXID by Chen, Puran, Bergman, Peter, Blennow, Ola, Hansson, Lotta, Mielke, Stephan, Nowak, Piotr, Söderdahl, Gunnar, Österborg, Anders, Smith, C.I. Edvard, Vesterbacka, Jan, Wullimann, David, Cuapio, Angelica, Akber, Mira, Bogdanovic, Gordana, Muschiol, Sandra, Åberg, Mikael, Loré, Karin, Sällberg Chen, Margaret, Buggert, Marcus, Ljungman, Per, Aleman, Soo, Ljunggren, Hans-Gustaf

“…Immunocompromised patients have varying responses to SARS-CoV-2 mRNA vaccination. However, there is limited information available from prospective clinical…”
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Differential Susceptibility to Human Immunodeficiency Virus Type 1 Infection of Myeloid and Plasmacytoid Dendritic Cells by SMED-SÖRENSEN, Anna, LORE, Karin, VASUDEVAN, Jayanand, LOUDER, Mark K, ANDERSSON, Jan, MASCOLA, John R, SPETZ, Anna-Lena, KOUP, Richard A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Modulation of innate immune response to mRNA vaccination after SARS-CoV-2 infection or sequential vaccination in humans by Hellgren, Fredrika, Rosdahl, Anja, Arcoverde Cerveira, Rodrigo, Lenart, Klara, Ols, Sebastian, Gwon, Yong-Dae, Kurt, Seta, Delis, Anna Maria, Joas, Gustav, Evander, Magnus, Normark, Johan, Ahlm, Clas, Forsell, Mattias Ne, Cajander, Sara, Loré, Karin

“…mRNA vaccines are likely to become widely used for the prevention of infectious diseases in the future. Nevertheless, a notable gap exists in mechanistic data,…”
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SARS-CoV-2 protein subunit vaccination of mice and rhesus macaques elicits potent and durable neutralizing antibody responses by Mandolesi, Marco, Sheward, Daniel J., Hanke, Leo, Ma, Junjie, Pushparaj, Pradeepa, Perez Vidakovics, Laura, Kim, Changil, Àdori, Monika, Lenart, Klara, Loré, Karin, Castro Dopico, Xaquin, Coquet, Jonathan M., McInerney, Gerald M., Karlsson Hedestam, Gunilla B., Murrell, Ben

“…The outbreak and spread of SARS-CoV-2 (severe acute respiratory syndrome-coronavirus-2) is a current global health emergency, and effective prophylactic…”
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Fcγ-Receptor-Independent Controlled Activation of CD40 Canonical Signaling by Novel Therapeutic Antibodies for Cancer Therapy by Beckmann, Karsten, Reitinger, Carmen, Yan, Xianglei, Carle, Anna, Blümle, Eva, Jurkschat, Nicole, Paulmann, Claudia, Prassl, Sandra, Kazandjian, Linda V, Loré, Karin, Nimmerjahn, Falk, Fischer, Stephan

“…The activation of CD40-mediated signaling in antigen-presenting cells is a promising therapeutic strategy to promote immune responses against tumors. Most…”
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Keratinocyte growth factor augments immune reconstitution after autologous hematopoietic progenitor cell transplantation in rhesus macaques by Seggewiss, Ruth, Loré, Karin, Guenaga, F. Javier, Pittaluga, Stefania, Mattapallil, Joseph, Chow, Catherine K., Koup, Richard A., Camphausen, Kevin, Nason, Martha C., Meier-Schellersheim, Martin, Donahue, Robert E., Blazar, Bruce R., Dunbar, Cynthia E., Douek, Daniel C.

“…Opportunistic infections contribute to morbidity and mortality after peripheral blood progenitor cell (PBPC) transplantation and are related to a deficient…”
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Infection of Specific Dendritic Cells by CCR5-Tropic Human Immunodeficiency Virus Type 1 Promotes Cell-Mediated Transmission of Virus Resistant to Broadly Neutralizing Antibodies by GANESH, Lakshmanan, LEUNG, Kwanyee, LORE, Karin, LEVIN, Reuven, PANET, Amos, SCHWARTZ, Owen, KOUP, Richard A, NABEL, Garv J

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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HIV-1-infected dendritic cells up-regulate cell surface markers but fail to produce IL-12 p70 in response to CD40 ligand stimulation by Smed-Sörensen, Anna, Loré, Karin, Walther-Jallow, Lilian, Andersson, Jan, Spetz, Anna-Lena

“…Dendritic cells (DCs) are antigen-presenting cells with the capacity to prime naive T cells for efficient cellular responses against pathogens such as HIV-1…”
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The Functional Profile of Primary Human Antiviral CD8+ T Cell Effector Activity Is Dictated by Cognate Peptide Concentration by Betts, Michael R, Price, David A, Brenchley, Jason M, Lore, Karin, Guenaga, F. Javier, Smed-Sorensen, Anna, Ambrozak, David R, Migueles, Stephen A, Connors, Mark, Roederer, Mario, Douek, Daniel C, Koup, Richard A

“…Antiviral CD8(+) T cells can elaborate at least two effector functions, cytokine production and cytotoxicity. Which effector function is elaborated can…”
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