Search Results - "Lopilato, Rachel K"

Canonical Notch ligands and Fringes have distinct effects on NOTCH1 and NOTCH2 by Kakuda, Shinako, LoPilato, Rachel K., Ito, Atsuko, Haltiwanger, Robert S.

“…Notch signaling is a cellular pathway regulating cell-fate determination and adult tissue homeostasis. Little is known about how canonical Notch ligands or…”
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O-Fucose and Fringe-modified NOTCH1 extracellular domain fragments as decoys to release niche-lodged hematopoietic progenitor cells by Yu, Shuiliang, Wang, Weihuan, Albakri, Marwah, Yu, Xiaoxing, Majihail, Gurnoor, Lim, Seunghwan, Lopilato, Rachel K, Ito, Atsuko, Letterio, John, Haltiwanger, Robert S, Zhou, Lan

“…Abstract Successful hematopoietic progenitor cell (HPC) transplant therapy is improved by mobilizing HPCs from the bone marrow niche in donors. Notch…”
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Two NOTCH1 O-fucose sites have opposing functions in mouse retinal angiogenesis by LoPilato, Rachel K, Kroeger, Heike, Mohan, Sneha K, Lauderdale, James D, Grimsey, Neil, Haltiwanger, Robert S

“…Abstract Previous in vitro studies demonstrated that Fringe glycosylation of the NOTCH1 extracellular domain at O-fucose residues in Epidermal Growth…”
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Isolation and characterization of new human carrier peptides from two important vaccine immunogens by Wantuch, Paeton L., Sun, Lina, LoPilato, Rachel K., Mousa, Jarrod J., Haltiwanger, Robert S., Avci, Fikri Y.

“…•We identified 11 MHCII-binding peptides generated from processing of TT and CRM197.•Each peptide is capable of stimulating human CD4+ T cells.•Donors have…”
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Genetic and biochemical evidence that gastrulation defects in Pofut2 mutants result from defects in ADAMTS9 secretion by Benz, Brian A., Nandadasa, Sumeda, Takeuchi, Megumi, Grady, Richard C., Takeuchi, Hideyuki, LoPilato, Rachel K., Kakuda, Shinako, Somerville, Robert P.T., Apte, Suneel S., Haltiwanger, Robert S., Holdener, Bernadette C.

“…Protein O-fucosyltransferase 2 (POFUT2) adds O-linked fucose to Thrombospondin Type 1 Repeats (TSR) in 49 potential target proteins. Nearly half the POFUT2…”
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O-Glycosylation and the Notch Signaling Pathway by LoPilato, Rachel K

“…The Notch signaling pathway is an evolutionarily conserved mechanism for cell-to-cell communication in metazoan development. Significant pathway regulation…”
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