Search Results - "Lopez Vacas, Rocio"
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Functional proteomics of colon cancer Consensus Molecular Subtypes
Published in British journal of cancer (01-06-2024)“…Background The Colorectal Cancer Subtyping Consortium established four Consensus Molecular Subtypes (CMS) in colorectal cancer: CMS1…”
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Utility of CYP2D6 copy number variants as prognostic biomarker in localized anal squamous cell carcinoma
Published in Cancer (15-08-2023)“…Background Anal squamous cell carcinoma (ASCC) is an infrequent tumor whose treatment has not changed since the 1970s. The aim of this study is the…”
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A novel approach to triple-negative breast cancer molecular classification reveals a luminal immune-positive subgroup with good prognoses
Published in Scientific reports (07-02-2019)“…Triple-negative breast cancer is a heterogeneous disease characterized by a lack of hormonal receptors and HER2 overexpression. It is the only breast cancer…”
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Molecular characterization of triple negative breast cancer formaldehyde‐fixed paraffin‐embedded samples by data‐independent acquisition proteomics
Published in Proteomics (Weinheim) (01-02-2022)“…Triple negative breast cancer accounts for 15%–20% of all breast carcinomas and is clinically characterized by an aggressive phenotype and poor prognosis…”
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Bayesian networks established functional differences between breast cancer subtypes
Published in PloS one (11-06-2020)“…Breast cancer is a heterogeneous disease. In clinical practice, tumors are classified as hormonal receptor positive, Her2 positive and triple negative tumors…”
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Prediction of adjuvant chemotherapy response in triple negative breast cancer with discovery and targeted proteomics
Published in PloS one (08-06-2017)“…Triple-negative breast cancer (TNBC) accounts for 15-20% of all breast cancers and usually requires the administration of adjuvant chemotherapy after surgery…”
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Description of the genetic variants identified in a cohort of patients diagnosed with localized anal squamous cell carcinoma and treated with panitumumab
Published in Scientific reports (01-04-2021)“…Squamous cell carcinoma is the most frequent histologic type of anal carcinoma. The standard of care since the 1970s has been a combination of 5-fluorouracil,…”
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Synergistic effect of antimetabolic and chemotherapy drugs in triple-negative breast cancer
Published in Biomedicine & pharmacotherapy (01-05-2022)“…The triple-negative breast cancer (TNBC) subtype comprises approximately 15% of all breast cancers and is associated with poor long-term outcomes. Classical…”
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miRNA profiling in renal carcinoma suggest the existence of a group of pro-angionenic tumors in localized clear cell renal carcinoma
Published in PloS one (28-02-2020)“…Renal cell carcinoma comprises a variety of entities, the most common being the clear-cell, papillary and chromophobe subtypes. These subtypes are related to…”
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Computational models applied to metabolomics data hints at the relevance of glutamine metabolism in breast cancer
Published in BMC cancer (15-04-2020)“…Metabolomics has a great potential in the development of new biomarkers in cancer and it has experiment recent technical advances. In this study, metabolomics…”
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Melanoma proteomics suggests functional differences related to mutational status
Published in Scientific reports (10-05-2019)“…Melanoma is the most lethal cutaneous cancer. New drugs have recently appeared; however, not all patients obtain a benefit of these new drugs. For this reason,…”
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PTRF/cavin-1 and MIF proteins are identified as non-small cell lung cancer biomarkers by label-free proteomics
Published in PloS one (26-03-2012)“…With the completion of the human genome sequence, biomedical sciences have entered in the "omics" era, mainly due to high-throughput genomics techniques and…”
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13
Tumor microbiota, consensus molecular subtype and survival in colon adenocarcinoma
Published in Journal of clinical oncology (01-06-2024)“…3607 Background: Microbiota can contribute to inflammation and tumor initiation and progression of colorectal cancer. The aim of this study was the…”
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14
Comprehensive Characterization of the Mutational Landscape in Localized Anal Squamous Cell Carcinoma
Published in Translational oncology (01-07-2020)“…Anal squamous cell carcinoma (ASCC) is a rare neoplasm. Chemoradiotherapy is the standard of care, with no therapeutic advances achieved over the past three…”
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15
Proteomics characterisation of central nervous system metastasis biomarkers in triple negative breast cancer
Published in Ecancermedicalscience (15-01-2019)“…Breast cancer (BC) is the most frequent tumour in women. Triple negative tumours (TNBC)-which are associated with minor survival rates-lack markers predictive…”
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Bio-miR: A prognostic microRNA-based signature for localized clear cell renal cell carcinoma
Published in Journal of clinical oncology (01-06-2022)“…e16519 Background: Prognosis of localized clear cell renal cell carcinoma (ccRCC) patients is estimated by nomograms based on clinico-pathological factors…”
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Shotgun proteomics of archival triple-negative breast cancer samples
Published in Proteomics. Clinical applications (01-04-2013)“…Purpose Triple‐negative breast cancer (TNBC) accounts for 15–20% of all breast cancers, and has a worse prognosis compared with hormone receptor‐positive…”
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Urothelial cancer proteomics provides both prognostic and functional information
Published in Scientific reports (17-11-2017)“…Traditionally, bladder cancer has been classified based on histology features. Recently, some works have proposed a molecular classification of invasive…”
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Characterisation of the triple negative breast cancer phenotype associated with the development of central nervous system metastases
Published in Ecancermedicalscience (11-04-2016)“…Breast cancer (BC) is the most frequent tumour in women, representing 20-30% of all malignancies, and continues to be the leading cause of cancer deaths among…”
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Abstract 5416: RNA-seq and proteomics to identify response to immunotherapy in advanced melanoma: a Spanish Melanoma Group Study
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Background: Prediction of response to immunotherapy remains an unmet need in the field of advanced melanoma. Methods: Computational analyses, including…”
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