Search Results - "Lopez De Cicco, Ricardo"

Simultaneous Expression of Furin and Vascular Endothelial Growth Factor in Human Oral Tongue Squamous Cell Carcinoma Progression by LOPEZ DE CICCO, Ricardo, WATSON, James C, BASSI, Daniel E, LITWIN, Samuel, KLEIN-SZANTO, Andrés J

“…Purpose: Squamous cell carcinoma (SCC) of the tongue is a common malignancy of the oral cavity. Furin convertase activates several precursor matrix…”
Get full text

Proprotein convertases: "Master switches" in the regulation of tumor growth and progression by Bassi, Daniel E., Fu, Jian, Lopez de Cicco, Ricardo, Klein-Szanto, Andres J.P.

“…Proprotein convertases (PCs) are a group of Ca2+‐dependent serine proteases that have homology to the endoproteases subtilisin (bacteria) and kexin (yeast)…”
Get full text

Furin Inhibition Results in Absent or Decreased Invasiveness and Tumorigenicity of Human Cancer Cells by Bassi, Daniel E., De Cicco, Ricardo Lopez, Mahloogi, Haleh, Zucker, Stanley, Thomas, Gary, Andres J. P. Klein-Szanto

“…Pro-protein convertases such as furin are expressed in many human tumor lines and primary tumors. Furin processes stromelysin-3, membrane type 1 matrix…”
Get full text

Pregnancy-induced chromatin remodeling in the breast of postmenopausal women by Russo, Jose, Santucci-Pereira, Julia, de Cicco, Ricardo López, Sheriff, Fathima, Russo, Patricia A., Peri, Suraj, Slifker, Michael, Ross, Eric, Mello, Maria Luiza S., Vidal, Benedicto C., Belitskaya-Lévy, Ilana, Arslan, Alan, Zeleniuch-Jacquotte, Anne, Bordas, Pal, Lenner, Per, Ahman, Janet, Afanasyeva, Yelena, Hallmans, Goran, Toniolo, Paolo, Russo, Irma H.

“…Early pregnancy and multiparity are known to reduce the risk of women to develop breast cancer at menopause. Based on the knowledge that the differentiation of…”
Get full text

Increased Furin Activity Enhances the Malignant Phenotype of Human Head and Neck Cancer Cells by Bassi, Daniel E., Mahloogi, Haleh, Lopez De Cicco, Ricardo, Klein-Szanto, Andres

“…Many proteins are synthesized as inactive proforms requiring a proteolytic processing to render them active. A variety of proteases catalyze these cleavage…”
Get full text

VILIP-1 expression in vivo results in decreased mouse skin keratinocyte proliferation and tumor development by Fu, Jian, Jin, Fang, Zhang, Jirong, Fong, Kathryn, Bassi, Daniel E, Lopez De Cicco, Ricardo, Ramaraju, Divya, Braunewell, Karl-Heinz, Conti, Claudio, Benavides, Fernando, Klein-Szanto, Andres J P

“…VILIP-1, a member of the neuronal Ca(2+) sensor protein family, is able to act as a tumor suppressor in carcinoma cells by inhibiting cell proliferation and…”
Get full text

Elevated furin expression in aggressive human head and neck tumors and tumor cell lines by Bassi, Daniel E., Mahloogi, Haleh, Al-Saleem, Luma, Lopez De Cicco, Ricardo, Ridge, John A., Klein-Szanto, Andres J. P.

“…Pro‐protein convertases (PCs) are proteases that recognize and cleave precursor proteins. Furin, a well‐studied PC, is ubiquitously expressed, and it has been…”
Get full text

Inhibition of Furin-mediated Processing Results in Suppression of Astrocytoma Cell Growth and Invasiveness by MERCAPIDE, Javier, LOPEZ DE CICCO, Ricardo, BASSI, Daniel E, CASTRESANA, Javier S, THOMAS, Gary, KLEIN-SZANTO, Andres J. P

“…Purpose: Astrocytoma arises in the central nervous system as a tumorof great lethality, in part because of the invasive potential of the neoplastic cells that…”
Get full text

Inhibition of proprotein convertases: Approaches to block squamous carcinoma development and progression by de Cicco, Ricardo López, Bassi, Daniel E., Benavides, Fernando, Conti, Claudio J., Klein-Szanto, Andrés J.P.

“…Most proprotein convertase (PC) inhibitors are compounds that act as competitive inhibitors. All of them contain the general cleavage motif RXK/RR that binds…”
Get full text

Fish Oil Alters Tamoxifen-Modulated Expression of mRNAs That Encode Genes Related to Differentiation, Proliferation, Metastasis, and Immune Response in Rat Mammary Tumors by Bidinotto, Lucas Tadeu, Cicco, Ricardo López de, Vanegas, Johana Erika, Santucci-Pereira, Julia, Heuvel, John Patrick Vanden, Washington, Sharlene, Aliaga, Cesar, Xu, Haifang, Russo, Irma H, Manni, Andrea, El-Bayoumy, Karam, Russo, Jose

“…We have previously shown that a fish oil (FO)-rich diet increased the chemopreventive efficacy of tamoxifen (Tam) against N-methyl-N-nitrosourea (MNU)-induced…”
Get full text

Genomic signature of parity in the breast of premenopausal women by Santucci-Pereira, Julia, Zeleniuch-Jacquotte, Anne, Afanasyeva, Yelena, Zhong, Hua, Slifker, Michael, Peri, Suraj, Ross, Eric A, López de Cicco, Ricardo, Zhai, Yubo, Nguyen, Theresa, Sheriff, Fathima, Russo, Irma H, Su, Yanrong, Arslan, Alan A, Bordas, Pal, Lenner, Per, Åhman, Janet, Landström Eriksson, Anna Stina, Johansson, Robert, Hallmans, Göran, Toniolo, Paolo, Russo, Jose

“…Full-term pregnancy (FTP) at an early age confers long-term protection against breast cancer. Previously, we reported that a FTP imprints a specific gene…”
Get full text

Human carcinoma cell growth and invasiveness is impaired by the propeptide of the ubiquitous proprotein convertase furin by LOPEZ DE CICCO, Ricardo, BASSI, Daniel E, ZUCKER, Stanley, SEIDAH, Nabil G, KLEIN-SZANTO, Andrés J. P

“…Furin, a potent proprotein convertase involved in activation of several cancer-related substrates, is synthesized as an inactive zymogen, thus minimizing the…”
Get full text

Oxidized derivative of docosahexaenoic acid preferentially inhibit cell proliferation in triple negative over luminal breast cancer cells by Pogash, Thomas J, El-Bayoumy, Karam, Amin, Shantu, Gowda, Krishne, de Cicco, Ricardo López, Barton, Maria, Su, Yanrong, Russo, Irma H, Himmelberger, Julie A, Slifker, Michael, Manni, Andrea, Russo, Jose

“…Omega-3 polyunsaturated fatty acids (PUFAs) exert an anticancer effect by affecting multiple cellular mechanisms leading to inhibition of proliferation and…”
Get full text

Characterization of a genomic signature of pregnancy identified in the breast by Belitskaya-Lévy, Ilana, Zeleniuch-Jacquotte, Anne, Russo, Jose, Russo, Irma H, Bordás, Pal, Ahman, Janet, Afanasyeva, Yelena, Johansson, Robert, Lenner, Per, Li, Xiaochun, de Cicco, Ricardo López, Peri, Suraj, Ross, Eric, Russo, Patricia A, Santucci-Pereira, Julia, Sheriff, Fathima S, Slifker, Michael, Hallmans, Göran, Toniolo, Paolo, Arslan, Alan A

“…The objective of this study was to comprehensively compare the genomic profiles in the breast of parous and nulliparous postmenopausal women to identify genes…”
Get full text

PACE4 expression in mouse basal keratinocytes results in basement membrane disruption and acceleration of tumor progression by BASSI, Daniel E, LOPEZ DE CICCO, Ricardo, CENNA, Jonathan, LITWIN, Samuel, CUKIERMAN, Edna, KLEIN-SZANTO, Andres J. P

“…Collagen type IV degradation results in disruption and breakdown of the normal basement membrane architecture, a key process in the initiation of tumor…”
Get full text

Omega-3 fatty acids: a potential booster for tamoxifen therapy? by Bidinotto, Lucas Tadeu, López de Cicco, Ricardo, Russo, Jose

Get full text

Stromelysin‐1/matrix metalloproteinase‐3 (MMP‐3) expression accounts for invasive properties of human astrocytoma cell lines by Mercapide, Javier, Lopez De Cicco, Ricardo, Castresana, Javier S., Klein‐Szanto, Andres J.P.

“…Tumor invasiveness is an intrinsic feature of most glial tumors that accounts for their malignant and locally destructive nature. We evaluated the subcutaneous…”
Get full text

Overexpression of the calcium sensor visinin-like protein-1 leads to a cAMP-mediated decrease of in vivo and in vitro growth and invasiveness of squamous cell carcinoma cells by MAHLOOGI, Haleh, GONZALEZ-GUERRICO, Anatilde M, LOPEZ DE CICCO, Ricardo, BASSI, Daniel E, GOODROW, Tamra, BRAUNEWELL, Karl-Heinz, KLEIN-SZANTO, Andres J. P

“…Visinin-like protein-1 (VILIP-1) is a member of the neuronal EF-hand Ca(2+)-sensor protein family. VILIP-1 is expressed in the central nervous system where it…”
Get full text

Defining the genomic signature of the parous breast by Peri, Suraj, de Cicco, Ricardo López, Santucci-Pereira, Julia, Slifker, Michael, Ross, Eric A, Russo, Irma H, Russo, Patricia A, Arslan, Alan A, Belitskaya-Lévy, Ilana, Zeleniuch-Jacquotte, Anne, Bordas, Pal, Lenner, Per, Åhman, Janet, Afanasyeva, Yelena, Johansson, Robert, Sheriff, Fathima, Hallmans, Göran, Toniolo, Paolo, Russo, Jose

“…It is accepted that a woman's lifetime risk of developing breast cancer after menopause is reduced by early full term pregnancy and multiparity. This…”
Get full text

Correction: Inhibition of Furin-mediated Processing Results in Suppression of Astrocytoma Cell Growth and Invasiveness by Mercapide, Javier, De Cicco, Ricardo Lopez, Bassi, Daniel E, Castresana, Javier S, Thomas, Gary, Klein-Szanto, Andres J P

Get full text