Search Results - "Lopez, Timothy"

EGFR Inhibition Enhances the Cellular Uptake and Antitumor-Activity of the HER3 Antibody-Drug Conjugate HER3-DXd by Haikala, Heidi M, Lopez, Timothy, Köhler, Jens, Eser, Pinar O, Xu, Man, Zeng, Qing, Teceno, Tyler J, Ngo, Kenneth, Zhao, Yutong, Ivanova, Elena V, Bertram, Arrien A, Leeper, Brittaney A, Chambers, Emily S, Adeni, Anika E, Taus, Luke J, Kuraguchi, Mari, Kirschmeier, Paul T, Yu, Channing, Shiose, Yoshinobu, Kamai, Yasuki, Qiu, Yang, Paweletz, Cloud P, Gokhale, Prafulla C, Jänne, Pasi A

“…Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI) are the standard-of-care treatment for -mutant non-small cell lung cancers (NSCLC)…”
Get full text

Lack of Correlation between Epidermal Growth Factor Receptor Status and Response to Panitumumab Monotherapy in Metastatic Colorectal Cancer by RANDOLPH HECHT, J, MITCHELL, Edith, NEUBAUER, Marcus A, BURRIS ILL, Howard A, SWANSON, Paul, LOPEZ, Timothy, BUCHANAN, Glenn, REINER, Maureen, GANSERT, Jennifer, BERLIN, Jordan

“…Panitumumab, a fully human anti-epidermal growth factor receptor (EGFR) monoclonal antibody, is approved as monotherapy for the treatment of metastatic…”
Get full text

Pedro de Godoy's De beatitudine naturali. Natural Happiness and its Possibility in Seventeenth-Century Thomism by López, Timothy J

“…Renaissance Thomists knew Thomas Aquinas spoke of natural happiness, but some believed this happiness is absolutely impossible; others impossible in a state of…”
Get full text

Variation of Anatomical and Physiological Parameters that Affect Estimates of ACL Loading During Drop Landing by Kernozek, Thomas W, Ragan, Robert J, Willson, John D, Koehler, Chelsey S, Lopez, Timothy R

“…Anterior cruciate ligament (ACL) loading during drop landing has been recently studied with a sagittal plane knee model developed by Kernozek and Ragan using…”
Get full text

Sa1337 – Exercise-Induced Myokines As a Mechanism for Pancreatic Cancer Protection: Potential Therapeutic Implications by Chen, Kay, Dela Cruz, Mart, Lopez, Timothy, Roy, Hemant K.

Get full text

Abstract 5192: EGFR inhibition enhances the cellular uptake and antitumor activity of the novel HER3 antibody drug conjugate U3-1402 by Haikala, Heidi M., Köhler, Jens, Lopez, Timothy, Eser, Pinar, Xu, Man, Yu, Channing, Shiose, Yoshinobu, Qiu, Yang, Gokhale, Prafulla, Jänne, Pasi A.

“…Abstract Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI) have changed the treatment landscape for EGFR-mutant non-small cell lung…”
Get full text

Oncogenic switch and single-agent MET inhibitor sensitivity in a subset of EGFR -mutant lung cancer by Eser, Pınar Özden, Paranal, Raymond M, Son, Jieun, Ivanova, Elena, Kuang, Yanan, Haikala, Heidi M, To, Ciric, Okoro, Jeffrey J, Dholakia, Kshiti H, Choi, Jihyun, Eum, Yoonji, Ogino, Atsuko, Missios, Pavlos, Ercan, Dalia, Xu, Man, Poitras, Michael J, Wang, Stephen, Ngo, Kenneth, Dills, Michael, Yanagita, Masahiko, Lopez, Timothy, Lin, Mika, Tsai, Jeanelle, Floch, Nicolas, Chambers, Emily S, Heng, Jennifer, Anjum, Rana, Santucci, Alison D, Michael, Kesi, Schuller, Alwin G, Cross, Darren, Smith, Paul D, Oxnard, Geoffrey R, Barbie, David A, Sholl, Lynette M, Bahcall, Magda, Palakurthi, Sangeetha, Gokhale, Prafulla C, Paweletz, Cloud P, Daley, George Q, Jänne, Pasi A

“…The clinical efficacy of epidermal growth factor receptor (EGFR)–targeted therapy in -mutant non–small cell lung cancer is limited by the development of drug…”
Get more information

Immuno-oncology combinations： raising the tail of the survival curve by Harris, Samuel J, Brown, Jessica, Lopez, Juanita, Yap, Timothy A

“…There have been exponential gains in immuno-oncology in recent times through the development of immune checkpoint inhibitors. Already approved by the U.S. Food…”
Get full text

Abstract 2319: Deep learning-enabled dynamic infiltration and response to NK therapies in solid tumor organoids by Lonini, Luca, Khare, Sonal, Lopez, Timothy Don, Szydlo, Stanislaw, Streit, Michael, Karginova, Olga A., Flaherty, Mary K., Salhaudeen, Ameen, Kunert, Andre, Oja, Anna, Sasser, Kate, Stumpe, Martin C., Ho, Chi-Sing

“…Abstract Patient-derived organoid co-culture models have become a state of the art platform to evaluate the effectiveness of immunotherapeutic agents in…”
Get full text

1283 Applying machine vision to empower preclinical development of immunotherapies in patient-derived organoid models of solid tumors by Chi-Sing, Ho, Khare, Sonal, Kannan, Madhavi, Streit, Michael, Lopez, Timothy, Lonini, Luca, Larsen, Brian, Mapes, Brandon, Shaxted, Jenna, Stumpe, Martin, Salahudeen, Ameen, Venkataraman, Jagadish

“…BackgroundParadigm shifting next-generation immuno-oncology therapeutics such as CAR-T cells and bispecific engagers are rapidly gaining interest as…”
Get full text

Evaluating The Anti-Proliferative Effects of Exercise on Colorectal Cancer Cell Lines HCT116 and HT29 Through Treatment of Myokines Produced from C2C12 Cells Subjected to Electric Pulse Stimulation by Lopez, Timothy Don Magno

“…Background: Colorectal cancer incidence and mortality rates are rising and are still one of the most common cancers worldwide. Its risks are associated with…”
Get full text

Abstract 199: Distinctive Roles of Linker Histone H1 Variants in the Hypertrophic Response of Cardiomyocytes by Parvatiyar, Michelle S, Lopez, Timothy D, Franklin, Sarah, Vondriska, Thomas M

“…Abstract only Heart failure results when cardiac output is insufficient to meet physiological requirements and is often preceded by development of…”
Get full text

Results of a multicenter open-label randomized trial evaluating infusion duration of zoledronic acid in multiple myeloma patients (the ZMAX trial) by Berenson, James R, Boccia, Ralph, Lopez, Timothy, Warsi, Ghulam M, Argonza-Aviles, Eliza, Lake, Simone, Ericson, Solveig G, Collins, Robert

“…Zoledronic acid, an intravenous (IV) bisphosphonate, is a standard treatment for multiple myeloma (MM) but may exacerbate preexisting renal dysfunction. The…”
Get more information

Results of a Phase II Open-Label Study of Capecitabine in Combination with Irinotecan as First-Line Treatment for Metastatic Colorectal Cancer by Cartwright, Thomas, Lopez, Timothy, Vukelja, Svetislava J., Encarnacion, Carlos, Boehm, Kristi A., Asmar, Lina

“…Between July 2001 and September 2002, 49 eligible patients were enrolled in an open-label phase II study to assess the efficacy and safety of first-line…”
Get full text

Small noncleaved cell lymphoma in adults: superior results for stages I-III disease by Lopez, T M, Hagemeister, F B, McLaughlin, P, Velasquez, W S, Swan, F, Redman, J R, Rodriguez, M A, Tucker, S L, Silvermintz, K, Johnson, J

“…Small noncleaved cell lymphoma (SNCCL), a rare lymphoma in adults, is associated with not only a rapid complete response (CR) to chemotherapy but also with the…”
Get more information

Amniotic fluid embolism associated with castor oil ingestion by Steingrub, J S, Lopez, T, Teres, D, Steingart, R

“…We report a case of an amniotic fluid embolism (AFE) causing a cardiorespiratory arrest associated temporally with ingestion of castor oil in a full-term…”
Get more information

Media sensations, contested sensibilities: Gender and moral order in the Egyptian mass media, 1920–1955 by Lopez, Shaun Timothy

“…This dissertation is about the rise of the mass media in Egypt and its implications for the representation and production of gender between 1920 and 1955. It…”
Get full text