Search Results - "Lopez, Santiago C"

Impact of Bivalent BA.4/5 BNT162b2 COVID-19 Vaccine on Acute Symptoms, Quality of Life, Work Productivity and Activity Levels among Symptomatic US Adults Testing Positive for SARS-CoV-2 at a National Retail Pharmacy by Di Fusco, Manuela, Sun, Xiaowu, Anatale-Tardiff, Laura, Yehoshua, Alon, Coetzer, Henriette, Alvarez, Mary B, Allen, Kristen E, Porter, Thomas M, Puzniak, Laura, Lopez, Santiago M. C, Cappelleri, Joseph C

“…Evidence on the impact of COVID-19 vaccination on symptoms, Health-Related Quality of Life (HRQoL) and Work Productivity and Activity Impairment (WPAI) is…”
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Effectiveness of BNT162b2 BA.4/5 Bivalent COVID-19 Vaccine against Long COVID Symptoms: A US Nationwide Study by Di Fusco, Manuela, Sun, Xiaowu, Allen, Kristen E, Yehoshua, Alon, Berk, Alexandra, Alvarez, Mary B, Porter, Thomas M, Ren, Jinma, Puzniak, Laura, Lopez, Santiago M C, Cappelleri, Joseph C

“…Long COVID has become a central public health concern. This study characterized the effectiveness of BNT162b2 BA.4/5 bivalent COVID-19 vaccine (bivalent)…”
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Impact of COVID-19 Infection on Health-Related Quality of Life, Work Productivity and Activity Impairment by Symptom-Based Long COVID Status and Age in the US by Di Fusco, Manuela, Cappelleri, Joseph C, Anatale-Tardiff, Laura, Coetzer, Henriette, Yehoshua, Alon, Alvarez, Mary B, Allen, Kristen E, Porter, Thomas M, Puzniak, Laura, Cha-Silva, Ashley S, Lopez, Santiago M C, Sun, Xiaowu

“…COVID-19 infection adversely impacts patients' wellbeing and daily lives. This survey-based study examined differences in patient-reported COVID-19 symptoms,…”
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Enabling methanol fixation of pediatric nasal wash during respiratory illness for single cell sequencing in comparison with fresh samples by Ismail, Khaled A., Mukherjee, Malini, Kareta, Michael S., Lopez, Santiago M. C.

“…Background Lower respiratory tract infection (LRTI) including pneumonia, bronchitis, and bronchiolitis is the sixth leading cause of mortality around the world…”
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Precise genome editing across kingdoms of life using retron-derived DNA by Lopez, Santiago C., Crawford, Kate D., Lear, Sierra K., Bhattarai-Kline, Santi, Shipman, Seth L.

“…Exogenous DNA can be a template to precisely edit a cell’s genome. However, the delivery of in vitro-produced DNA to target cells can be inefficient, and low…”
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Recording gene expression order in DNA by CRISPR addition of retron barcodes by Bhattarai-Kline, Santi, Lear, Sierra K., Fishman, Chloe B., Lopez, Santiago C., Lockshin, Elana R., Schubert, Max G., Nivala, Jeff, Church, George M., Shipman, Seth L.

“…Biological processes depend on the differential expression of genes over time, but methods to make physical recordings of these processes are limited. Here we…”
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Temporally resolved transcriptional recording in E. coli DNA using a Retro-Cascorder by Lear, Sierra K., Lopez, Santiago C., González-Delgado, Alejandro, Bhattarai-Kline, Santi, Shipman, Seth L.

“…Biological signals occur over time in living cells. Yet most current approaches to interrogate biology, particularly gene expression, use destructive…”
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Simultaneous multi-site editing of individual genomes using retron arrays by González-Delgado, Alejandro, Lopez, Santiago C., Rojas-Montero, Matías, Fishman, Chloe B., Shipman, Seth L.

“…During recent years, the use of libraries-scale genomic manipulations scaffolded on CRISPR guide RNAs have been transformative. However, these existing…”
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Differences in Antibody Responses Between Trivalent Inactivated Influenza Vaccine and Live Attenuated Influenza Vaccine Correlate With the Kinetics and Magnitude of Interferon Signaling in Children by Cao, Raquel G., Suarez, Nicolas M., Obermoser, Gerlinde, Lopez, Santiago M. C., Flano, Emilio, Mertz, Sara E., Albrecht, Randy A., Garcia-Sastre, Adolfo, Mejias, Asuncion, Xu, Hui, Qin, Huanying, Blankenship, Derek, Palucka, Karolina, Pascual, Virginia, Ramilo, Octavio

“…Background. Live attenuated influenza vaccine (LAIV) and trivalent inactivated influenza vaccine (TIV) are effective for prevention of influenza virus…”
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An experimental census of retrons for DNA production and genome editing by Khan, Asim G, Rojas-Montero, Matías, González-Delgado, Alejandro, Lopez, Santiago C, Fang, Rebecca F, Crawford, Kate D, Shipman, Seth L

“…Retrons are bacterial immune systems that use reverse-transcribed DNA (RT-DNA) to detect phage infection. They are also deployed for genome editing, where they…”
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Increased disease severity during COVID-19 related hospitalization in black non-hispanic, hispanic and medicaid-insured young children by Ochapa, Monica Oyidu, McGrath, Leah J, Alfred, Tamuno, Lopez, Santiago M C, Nepal, Rajeev M

“…The COVID-19 pandemic has disproportionately affected marginalized groups in the United States. Although most children have mild or asymptomatic COVID-19, some…”
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Mediterranean landscapes under change: Combining social multicriteria evaluation and the ecosystem services framework for land use planning by Martínez-Sastre, R., Ravera, F., González, J.A., López Santiago, C., Bidegain, I., Munda, G.

“…[Display omitted] •Social multicriteria evaluation provides insights for policy planning in threatened cultural landscapes.•Biophysical and social evaluations…”
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Clinical outcomes of COVID-19 and influenza in hospitalized children <5 years in the US by McGrath, Leah J., Moran, Mary M., Alfred, Tamuno, Reimbaeva, Maya, Di Fusco, Manuela, Khan, Farid, Welch, Verna L., Malhotra, Deepa, Cane, Alejandro, Lopez, Santiago M. C.

“…IntroductionWe compared hospitalization outcomes of young children hospitalized with COVID-19 to those hospitalized with influenza in the United States…”
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Exploring social-ecological systems in the transition from war to peace: A scenario-based approach to forecasting the post-conflict landscape in a Colombian region by Zúñiga-Upegui, P., Arnaiz-Schmitz, C., Herrero-Jáuregui, C., Smart, S.M., López-Santiago, C.A., Schmitz, M.F.

“…This paper describes the relationship between the landscape and the socio-economic and political characteristics of a highly biodiverse Andean region of…”
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Viral Coinfection and Nasal Cytokines in Children With Clinically Diagnosed Acute Sinusitis by Lopez, Santiago M C, Shaikh, Nader, Johnson, Monika, Liu, Hui, Martin, Judith M, Williams, John V

“…Children with no pathogenic bacteria in the nasopharynx are unlikely to have acute bacterial sinusitis. We evaluated whether information on clinical…”
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“Hot Tub Lung” With M. avium complex in an Immunocompetent Adolescent by Waletzko, Benjamin, Lin, Philana Ling, Lopez, Santiago M.C.

“…We describe a case of pulmonary Mycobacterium avium complex (MAC) infection in an immunocompetent pediatric patient after a hot tub near drowning event with a…”
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High Clinical Burden of Influenza Disease in Adults Aged ≥ 65 Years: Can We Do Better? A Systematic Literature Review by Langer, Jakob, Welch, Verna L., Moran, Mary M., Cane, Alejandro, Lopez, Santiago M. C., Srivastava, Amit, Enstone, Ashley L., Sears, Amy, Markus, Kristen J., Heuser, Maria, Kewley, Rachel M., Whittle, Isabelle J.

“…Introduction Influenza is a respiratory infection associated with a significant clinical burden globally. Adults aged ≥ 65 years are at increased risk of…”
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Disparities in Outcomes During Lower Respiratory Tract Infection in American Indian Children: A 9-Year Retrospective Analysis in a Rural Population in South Dakota by Palmer, Geralyn M., Kooima, Travis R., Van Hove, Christopher M., Withrow, Landon L., Gurumoorthy, Aarabhi, Lopez, Santiago M.C.

“…American Indian (AI) children are at increased risk for severe disease during lower respiratory tract infection (LRTI). The reasons for this increased severity…”
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Understanding the Global Burden of Influenza in Adults Aged 18–64 years: A Systematic Literature Review from 2012 to 2022 by Maleki, Farzaneh, Welch, Verna, Lopez, Santiago M. C., Cane, Alejandro, Langer, Jakob, Enstone, Ashley, Markus, Kristen, Wright, Olivia, Hewitt, Nicole, Whittle, Isabelle

“…Introduction Adults aged 18–64 years comprise most of the working population, meaning that influenza infection can be disruptive, causing prolonged absence…”
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The Cost of Seasonal Influenza: A Systematic Literature Review on the Humanistic and Economic Burden of Influenza in Older (≥ 65 Years Old) Adults by Langer, Jakob, Welch, Verna L., Moran, Mary M., Cane, Alejandro, Lopez, Santiago M. C., Srivastava, Amit, Enstone, Ashley, Sears, Amy, Markus, Kristen, Heuser, Maria, Kewley, Rachel, Whittle, Isabelle

“…Introduction Adults aged ≥ 65 years contribute a large proportion of influenza-related hospitalizations and deaths due to increased risk of complications,…”
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