Search Results - "Lopez, Pablo HH"
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Biosynthesis of the major brain gangliosides GD1a and GT1b
Published in Glycobiology (Oxford) (01-10-2012)“…Gangliosides-sialylated glycosphingolipids-are the major glycoconjugates of nerve cells. The same four structures-GM1, GD1a, GD1b and GT1b-comprise the great…”
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Gangliosides in cell recognition and membrane protein regulation
Published in Current opinion in structural biology (01-10-2009)“…Gangliosides, sialic acid-bearing glycosphingolipids, are expressed on all vertebrate cells, and are the major glycans on nerve cells. They are anchored to the…”
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Mice lacking sialyltransferase ST3Gal-II develop late-onset obesity and insulin resistance
Published in Glycobiology (Oxford) (01-01-2017)“…Sialyltransferases are a family of 20 gene products in mice and humans that transfer sialic acid from its activated precursor, CMP-sialic acid, to the terminus…”
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Gangliosides and Nogo Receptors Independently Mediate Myelin-associated Glycoprotein Inhibition of Neurite Outgrowth in Different Nerve Cells
Published in The Journal of biological chemistry (21-09-2007)“…In the injured nervous system, myelin-associated glycoprotein (MAG) on residual myelin binds to receptors on axons, inhibits axon outgrowth, and limits…”
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Passive Immunization with Anti-Ganglioside Antibodies Directly Inhibits Axon Regeneration in an Animal Model
Published in The Journal of neuroscience (03-01-2007)“…Recent studies have proposed that neurite outgrowth is influenced by specific nerve cell surface gangliosides, which are sialic acid-containing…”
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Myelin-associated glycoprotein protects neurons from excitotoxicity
Published in Journal of neurochemistry (01-03-2011)“…J. Neurochem. (2011) 116, 900-908. ABSTRACT: In addition to supporting rapid nerve conduction, myelination nurtures and stabilizes axons and protects them from…”
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