Search Results - "Lopez, L. O."

Age, Alzheimer disease, and brain structure by RAJI, C. A, LOPEZ, O. L, KULLER, L. H, CARMICHAEL, O. T, BECKER, J. T

“…Lack of clear understanding remains on the overlapping atrophy patterns of aging and early Alzheimer disease (AD) pathology in gray matter (GM) of the brain in…”
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Physical activity predicts gray matter volume in late adulthood: The Cardiovascular Health Study by ERICKSON, K. I, RAJI, C. A, LOPEZ, O. L, BECKER, J. T, ROSANO, C, NEWMAN, A. B, GACH, H. M, THOMPSON, P. M, HO, A. J, KULLER, L. H

“…Physical activity (PA) has been hypothesized to spare gray matter volume in late adulthood, but longitudinal data testing an association has been lacking. Here…”
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Predicting risk of dementia in older adults: The late-life dementia risk index by BARNES, D. E, COVINSKY, K. E, WHITMER, R. A, KULLER, L. H, LOPEZ, O. L, YAFFE, K

“…To develop a late-life dementia risk index that can accurately stratify older adults into those with a low, moderate, or high risk of developing dementia…”
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Diagnosis and management of dementia with Lewy bodies: Third report of the DLB consortium by McKeith, Ian G, Dickson, Dennis W, Lowe, James, Emre, Murat, Obrien, John T, Feldman, Howard, Cummings, Jeffrey L, Duda, John E, Lippa, Carol F, Perry, Elaine k, Aarsland, Dag, Arai, Hiroyuki, Ballard, Clive G, Boeve, Bradley F, Burn, David J, Costa, Durval Campos, Del Ser, Teodoro, Dubois, Bruno, Galasko, Douglas, Gauthier, Serge, Goetz, Christopher G, Gomez-Tortosa, Estrella, Halliday, Glenda, Hansen, Lawrence A, Hardy, John, Iwatsubo, Takeshi, Kalaria, Raj N, Kaufer, Daniel, Kenny, Rose Anne, Korczyn, Amos D, Kosaka, Kenji, Lee, Virginia Man-Yee, Lees, Andrew, Litvan, Irene, Londos, Elisabet, Lopez, Oscar L, Minoshima, Satoshi, Mizuno, Yoshikuni, Molina, Jose Antonio, Mukaetova-Ladinska, Elizabeta B, Pasquier, Florence, Perry, Robert H, Schulz, Jorg B, Trojanowski, John Q, Yamada, Masahito

“…The dementia with Lewy bodies (DLB) Consortium has revised criteria for the clinical and pathologic diagnosis of DLB incorporating new information about the…”
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Late-life depression and increased risk of dementia: a longitudinal cohort study by Ly, M., Karim, H. T., Becker, J. T., Lopez, O. L., Anderson, S. J., Aizenstein, H. J., Reynolds, C. F., Zmuda, M. D., Butters, M. A.

“…Late-life depression (LLD) is associated with an increased risk of developing dementia; however, it is not known whether individuals with a history of LLD…”
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Long-term effects of the concomitant use of memantine with cholinesterase inhibition in Alzheimer disease by Lopez, O L, Becker, J T, Wahed, A S, Saxton, J, Sweet, R A, Wolk, D A, Klunk, W, DeKosky, S T

“…Background:Patients using cholinesterase inhibitors (ChEIs) have a delay in nursing home (NH) admission compared with those who were not using the medication…”
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Genome-wide association analysis of age-at-onset in Alzheimer's disease by Kamboh, M I, Barmada, M M, Demirci, F Y, Minster, R L, Carrasquillo, M M, Pankratz, V S, Younkin, S G, Saykin, A J, Sweet, R A, Feingold, E, DeKosky, S T, Lopez, O L

“…The risk of Alzheimer's disease (AD) is strongly determined by genetic factors and recent genome-wide association studies (GWAS) have identified several genes…”
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ATP5H/KCTD2 locus is associated with Alzheimer's disease risk by Boada, M, Antúnez, C, Ramírez-Lorca, R, DeStefano, A L, González-Pérez, A, Gayán, J, López-Arrieta, J, Ikram, M A, Hernández, I, Marín, J, Galán, J J, Bis, J C, Mauleón, A, Rosende-Roca, M, Moreno-Rey, C, Gudnasson, V, Morón, F J, Velasco, J, Carrasco, J M, Alegret, M, Espinosa, A, Vinyes, G, Lafuente, A, Vargas, L, Fitzpatrick, A L, Launer, L J, Sáez, M E, Vázquez, E, Becker, J T, López, O L, Serrano-Ríos, M, Tárraga, L, van Duijn, C M, Real, L M, Seshadri, S, Ruiz, A

“…To identify loci associated with Alzheimer disease, we conducted a three-stage analysis using existing genome-wide association studies (GWAS) and genotyping in…”
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Plasma amyloid levels and the risk of AD in normal subjects in the Cardiovascular Health Study by LOPEZ, O. L, KULLER, L. H, MEHTA, P. D, BECKER, J. T, GACH, H. M, SWEET, R. A, CHANG, Y. F, TRACY, R, DEKOSKY, S. T

“…To examine the association between incident Alzheimer disease (AD), and plasma A beta 1-40 and A beta 1-42 levels in normal and mild cognitive impairment (MCI)…”
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Genome-wide association study of Alzheimer's disease with psychotic symptoms by Hollingworth, P, Sweet, R, Sims, R, Harold, D, Russo, G, Abraham, R, Stretton, A, Jones, N, Gerrish, A, Chapman, J, Ivanov, D, Moskvina, V, Lovestone, S, Priotsi, P, Lupton, M, Brayne, C, Gill, M, Lawlor, B, Lynch, A, Craig, D, McGuinness, B, Johnston, J, Holmes, C, Livingston, G, Bass, N J, Gurling, H, McQuillin, A, Holmans, P, Jones, L, Devlin, B, Klei, L, Barmada, M M, Demirci, F Y, DeKosky, S T, Lopez, O L, Passmore, P, Owen, M J, O'Donovan, M C, Mayeux, R, Kamboh, M I, Williams, J

“…Psychotic symptoms occur in ∼40% of subjects with Alzheimer's disease (AD) and are associated with more rapid cognitive decline and increased functional…”
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Functional and cognitive criteria produce different rates of mild cognitive impairment and conversion to dementia by Saxton, J, Snitz, B E, Lopez, O L, Ives, D G, Dunn, L O, Fitzpatrick, A, Carlson, M C, DeKosky, S T

“…Objective:To compare rates of mild cognitive impairment (MCI) and rates of progression to dementia using different MCI diagnostic systems.Methods:MCI was…”
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Determinants of vascular dementia in the Cardiovascular Health Cognition Study by KULLER, L. H, LOPEZ, O. L, JAGUST, W. J, BECKER, J. T, DEKOSKY, S. T, LYKETSOS, C, KAWAS, C, BREITNER, J. C. S, FITZPATRICK, A, DULBERG, C

“…The authors evaluated 3,375 participants without dementia at the time of MRI in 1991 to 1994 over 5.7 years for incident dementia and type of dementia…”
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Using microfluidics to control soft adhesion by Prieto-López, L. O., Williams, J. A.

“…We demonstrate that the inclusion of subsurface microfluidic features in a soft polymer surface, whose internal pressure can be varied, may be used to modify…”
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Physical activity, inflammation, and volume of the aging brain by Braskie, M.N, Boyle, C.P, Rajagopalan, P, Gutman, B.A, Toga, A.W, Raji, C.A, Tracy, R.P, Kuller, L.H, Becker, J.T, Lopez, O.L, Thompson, P.M

“…Highlights • Physical activity influences inflammation, and both affect brain structure. • We studied how physical activity and inflammation relate to later…”
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A genome-wide association meta-analysis of plasma Aβ peptides concentrations in the elderly by Chouraki, V, De Bruijn, R F A G, Chapuis, J, Bis, J C, Reitz, C, Schraen, S, Ibrahim-Verbaas, C A, Grenier-Boley, B, Delay, C, Rogers, R, Demiautte, F, Mounier, A, Fitzpatrick, A L, Berr, C, Dartigues, J-F, Uitterlinden, A G, Hofman, A, Breteler, M, Becker, J T, Lathrop, M, Schupf, N, Alpérovitch, A, Mayeux, R, van Duijn, C M, Buée, L, Amouyel, P, Lopez, O L, Ikram, M A, Tzourio, C, Lambert, J-C

“…Amyloid beta (Aβ) peptides are the major components of senile plaques, one of the main pathological hallmarks of Alzheimer disease (AD). However, Aβ peptides'…”
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Correction: Genetic risk for schizophrenia and psychosis in Alzheimer disease by DeMichele-Sweet, M. A. A., Weamer, E. A., Klei, L., Vrana, D. T., Hollingshead, D. J., Seltman, H. J., Sims, R., Foroud, T., Hernandez, I., Moreno-Grau, S., Tárraga, L., Boada, M., Ruiz, A., Williams, J., Mayeux, R., Lopez, O. L., Sibille, E. L., Kamboh, M. I., Devlin, B., Sweet, R. A.

“…A number of collaborators were not acknowledged for their contribution to this published article. The acknowledgements that were missing in this published…”
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Targeting the post-synaptic proteome has therapeutic potential for psychosis in Alzheimer Disease by Krivinko, J. M., DeChellis-Marks, M. R., Zeng, L., Fan, P., Lopez, O. L., Ding, Y., Wang, L., Kofler, J., MacDonald, M. L., Sweet, R. A.

“…Individuals with Alzheimer Disease who develop psychotic symptoms (AD + P) experience more rapid cognitive decline and have reduced indices of synaptic…”
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Phenotypic variability in three families with valosin-containing protein mutation by Spina, S., Van Laar, A. D., Murrell, J. R., Hamilton, R. L., Kofler, J. K., Epperson, F., Farlow, M. R., Lopez, O. L., Quinlan, J., DeKosky, S. T., Ghetti, B.

“…Background and purpose The phenotype of IBMPFD [inclusion body myopathy with Paget's disease of the bone and frontotemporal dementia (FTD)] associated with…”
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Preclinical Alzheimer disease: Neuropsychological test performance 1.5 to 8 years prior to onset by SAXTON, J, LOPEZ, O. L, RATCLIFF, G, DULBERG, C, FRIED, L. P, CARLSON, M. C, NEWMAN, A. B, KULLER, L

“…To determine if individuals ultimately diagnosed with Alzheimer disease (AD) exhibited evidence of cognitive impairment on neuropsychological tests…”
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Cholinesterase inhibitor treatment alters the natural history of Alzheimer's disease by Lopez, O L, Becker, J T, Wisniewski, S, Saxton, J, Kaufer, D I, DeKosky, S T

“…Objective: To describe the effect of cholinesterase inhibitors (CEIs) on the natural course of Alzheimer's disease (AD). Methods: The short and long term…”
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