Search Results - "Lopez, Ignazio"
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Safety and efficacy of nabiximols on spasticity symptoms in patients with motor neuron disease (CANALS): a multicentre, double-blind, randomised, placebo-controlled, phase 2 trial
Published in Lancet neurology (01-02-2019)“…Spasticity is a major determinant of disability and decline in quality of life in patients with motor neuron disease. Cannabinoids have been approved for…”
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Peripheral nerve morphogenesis induced by scaffold micropatterning
Published in Biomaterials (01-04-2014)“…Abstract Several bioengineering approaches have been proposed for peripheral nervous system repair, with limited results and still open questions about the…”
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Mitochondrial biogenesis and fission in axons in cell culture and animal models of diabetic neuropathy
Published in Acta neuropathologica (01-10-2010)“…Mitochondrial-mediated oxidative stress in response to high glucose is proposed as a primary cause of dorsal root ganglia (DRG) neuron injury in the…”
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Balance exercise in patients with chronic sensory ataxic neuropathy: a pilot study
Published in Journal of the peripheral nervous system (01-06-2014)“…Although exercise therapy is considered part of the treatment of neuropathic patients, and somatosensory input is essential for motor learning, performance and…”
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Corneal and Epidermal Nerve Quantification in Chemotherapy Induced Peripheral Neuropathy
Published in Frontiers in medicine (18-02-2022)“…Chemotherapy-induced neurotoxicity is an increasingly recognized clinical issue in oncology. confocal microscopy (IVCM) of corneal nerves has been successfully…”
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Laser capture microdissection for transcriptomic profiles in human skin biopsies
Published in BMC molecular biology (19-06-2018)“…The acquisition of reliable tissue-specific RNA sequencing data from human skin biopsy represents a major advance in research. However, the complexity of the…”
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Diffuse intraneural leiomyoma in a case of sensorimotor neuropathy
Published in Acta neuropathologica (01-05-2009)Get full text
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The brachial plexus branches to the pectoral muscles in adult rats: morphological aspects and morphometric normative data
Published in Frontiers in neuroanatomy (10-10-2012)“…Animal models provide an important tool to investigate the pathogenesis of neuromuscular disorders. In the present study, we analyze fiber composition of the…”
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Lentiviral haemopoietic stem-cell gene therapy in early-onset metachromatic leukodystrophy: an ad-hoc analysis of a non-randomised, open-label, phase 1/2 trial
Published in The Lancet (British edition) (30-07-2016)“…Summary Background Metachromatic leukodystrophy (a deficiency of arylsulfatase A [ARSA]) is a fatal demyelinating lysosomal disease with no approved treatment…”
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Best practices for the management of thymic epithelial tumors: A position paper by the Italian collaborative group for ThYmic MalignanciEs (TYME)
Published in Cancer treatment reviews (01-12-2018)“…•TETs are rare and heterogeneous tumors with complex multidisciplinary management.•Although guidelines are available there is inhomogeneity in their…”
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Network topology of NaV1.7 mutations in sodium channel-related painful disorders
Published in BMC systems biology (24-02-2017)“…Gain-of-function mutations in SCN9A gene that encodes the voltage-gated sodium channel NaV1.7 have been associated with a wide spectrum of painful syndromes in…”
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Foot pad skin biopsy in mouse models of hereditary neuropathy
Published in Glia (01-12-2010)“…Numerous transgenic and knockout mouse models of human hereditary neuropathies have become available over the past decade. We describe a simple, reproducible,…”
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Diffuse intraneural leiomyoma in a case of sensorimotor neuropathy
Published in Acta neuropathologica (01-05-2009)Get full text
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