Search Results - "Lopez, Gloria V"

Sensitive detection and estimation of cell-derived peroxynitrite fluxes using fluorescein-boronate by Rios, Natalia, Piacenza, Lucía, Trujillo, Madia, Martínez, Alejandra, Demicheli, Verónica, Prolo, Carolina, Álvarez, María Noel, López, Gloria V., Radi, Rafael

“…The specific and sensitive detection of peroxynitrite (ONOO−/ONOOH) in biological systems is a great challenge due to its high reactivity towards several…”
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A novel nitroalkene‐α‐tocopherol analogue inhibits inflammation and ameliorates atherosclerosis in Apo E knockout mice by Rodriguez‐Duarte, Jorge, Galliussi, Germán, Dapueto, Rosina, Rossello, Jessica, Malacrida, Leonel, Kamaid, Andrés, Schopfer, Francisco J, Escande, Carlos, López, Gloria V, Batthyány, Carlos

“…Background and purpose Atherosclerosis is characterized by chronic low‐grade inflammation with concomitant lipid accumulation in the arterial wall…”
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A green multicomponent synthesis of tocopherol analogues with antiproliferative activities by Ingold, Mariana, Dapueto, Rosina, Victoria, Sabina, Galliusi, Germán, Batthyàny, Carlos, Bollati-Fogolín, Mariela, Tejedor, David, García-Tellado, Fernando, Padrón, José M., Porcal, Williams, López, Gloria V.

“…A one-pot efficient, practical and eco-friendly synthesis of tocopherol analogues has been developed using water or solvent free conditions via Passerini and…”
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Second Generation Drug-Eluting Stents for Endovascular Treatment of Ostial Vertebral Artery Stenosis: A Single Center Experience by Ortega-Gutierrez, Santiago, Lopez, Gloria V, Edgell, Randall C, Mendez, Aldo A, Dandapat, Sudeepta, Roa, Jorge A, Zevallos, Cynthia B, Holcombe, Andrea L, Hasan, David, Derdeyn, Colin P, Rossen, James, Samaniego, Edgar A

“…To report a single-center experience using drug-eluting balloon mounted stents (DES) for endovascular treatment of atherosclerotic ostial vertebral artery…”
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Stent‐Assisted Coiling Versus Balloon‐Assisted Coiling for the Treatment of Ruptured Wide‐Necked Aneurysms: A 2‐Center Experience by Vivanco‐Suarez, Juan, Wallace, Adam N., Dandapat, Sudeepta, Lopez, Gloria V., Mendez‐Ruiz, Aldo, Kayan, Yasha, Copelan, Alexander Z., Dajles, Andres, Zevallos, Cynthia B., Quispe‐Orozco, Darko, Mendez‐Ruiz, Alan, Galecio‐Castillo, Milagros, Samaniego, Edgar A., Farooqui, Mudassir, Delgado, Josser E., Ortega‐Gutierrez, Santiago

“…Background Balloon‐assisted coiling (BAC) and stent‐assisted coiling (SAC) have been established as feasible approaches to manage ruptured wide‐necked…”
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6-Methylnitroarachidonate: A novel esterified nitroalkene that potently inhibits platelet aggregation and exerts cGMP-mediated vascular relaxation by Blanco, Fabiana, Ferreira, Ana M., López, Gloria V., Bonilla, Lucía, González, Mercedes, Cerecetto, Hugo, Trostchansky, Andrés, Rubbo, Homero

“…Nitro-fatty acids represent endogenously occurring products of oxidant-induced nitration reactions. We have previously synthesized a mixture of four isomers of…”
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Second generation of α-tocopherol analogs-nitric oxide donors: Synthesis, physicochemical, and biological characterization by López, Gloria V., Blanco, Fabiana, Hernández, Paola, Ferreira, Ana, Piro, Oscar E., Batthyány, Carlos, González, Mercedes, Rubbo, Homero, Cerecetto, Hugo

“…Synthesis, physicochemical, and biological characterization of second generation series of products obtained by coupling α-tocopherol or analogs through…”
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Decreases in Blood Pressure During Thrombectomy Are Associated With Larger Infarct Volumes and Worse Functional Outcome by Petersen, Nils H, Ortega-Gutierrez, Santiago, Wang, Anson, Lopez, Gloria V, Strander, Sumita, Kodali, Sreeja, Silverman, Andrew, Zheng-Lin, Binbin, Dandapat, Sudeepta, Sansing, Lauren H, Schindler, Joseph L, Falcone, Guido J, Gilmore, Emily J, Amin, Hardik, Cord, Branden, Hebert, Ryan M, Matouk, Charles, Sheth, Kevin N

“…BACKGROUND AND PURPOSE—After large-vessel intracranial occlusion, the fate of the ischemic penumbra, and ultimately final infarct volume, largely depends on…”
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Interaction studies between human α-tocopherol transfer protein and nitric oxide donor tocopherol analogues with LDL-protective activity by López, Gloria V., Gómez, Luis E., Campillo, Nuria, Páez, Juan A., Giles, Kaleigh, Atkinson, Jeffrey, González, Mercedes, Rubbo, Homero, Cerecetto, Hugo

“…Nitric oxide-releasing α-tocopherol mimetics with LDL-protective activity were designed to maintain the tocopherol substructure necessary for its biochemical…”
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Genetic toxicology and preliminary in vivo studies of nitric oxide donor tocopherol analogs as potential new class of antiatherogenic agents by Cabrera, Mauricio, López, Gloria V., Gómez, Luis E., Breijo, Martín, Pintos, Cristina, Botti, Horacio, Raymondo, Stella, Vettorazzi, Ariane, Ceráin, Adela López de, Monge, Antonio, Rubbo, Homero, González, Mercedes, Cerecetto, Hugo

“…Nitric oxide donor tocopherol analogs were found to be incorporated in low-density lipoprotein to release nitric oxide into the hydrophobic core of the…”
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Greener Synthesis of Antiproliferative Furoxans via Multicomponent Reactions by Ingold, Mariana, de la Sovera, Victoria, Dapueto, Rosina, Hernández, Paola, Porcal, Williams, López, Gloria V

“…Prostate and bladder cancers are commonly diagnosed malignancies in men. Several nitric oxide donor compounds with strong antitumor activity have been…”
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Transverse venous sinus stenting for idiopathic intracranial hypertension: Safety and feasibility by Koovor, Jerry ME, Lopez, Gloria V, Riley, Kalen, Tejada, Juan

“…Purpose Transverse sinus stenosis is commonly seen in patients with idiopathic intracranial hypertension. It is not clear whether it is the cause or the result…”
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Furoxans and tocopherol analogs–furoxan hybrids as anticancer agents by Pérez, Florencia, Varela, María, Canclini, Lucía, Acosta, Silvina, Martínez-López, Wilner, López, Gloria V, Hernández, Paola

“…We determined the antiproliferative and nitric oxide (NO)-releasing activity of furoxans and tocopherol analogs–furoxan hybrids by tandem…”
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A novel nitroalkene vitamin E analogue inhibits the NLRP3 inflammasome and protects against inflammation and glucose intolerance triggered by obesity by Dapueto, Rosina, Rodriguez-Duarte, Jorge, Galliussi, Germán, Kamaid, Andrés, Bresque, Mariana, Batthyány, Carlos, López, Gloria V., Escande, Carlos

“…Chronic metabolic diseases, like obesity, type II diabetes and atherosclerosis often involve a low-grade and sterile systemic inflammatory state, in which…”
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Electrophilic nitroalkene-tocopherol derivatives: synthesis, physicochemical characterization and evaluation of anti-inflammatory signaling responses by Rodriguez-Duarte, Jorge, Dapueto, Rosina, Galliussi, Germán, Turell, Lucía, Kamaid, Andrés, Khoo, Nicholas K. H., Schopfer, Francisco J., Freeman, Bruce A., Escande, Carlos, Batthyány, Carlos, Ferrer-Sueta, Gerardo, López, Gloria V.

“…Inflammation plays a major role in the onset and development of chronic non-communicable diseases like obesity, cardiovascular diseases and cancer. Combined,…”
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A Nitroalkene Benzoic Acid Derivative Targets Reactive Microglia and Prolongs Survival in an Inherited Model of ALS via NF-κB Inhibition by Ibarburu, Sofía, Kovacs, Mariángeles, Varela, Valentina, Rodríguez-Duarte, Jorge, Ingold, Mariana, Invernizzi, Paulina, Porcal, Williams, Arévalo, Ana Paula, Perelmuter, Karen, Bollati-Fogolín, Mariela, Escande, Carlos, López, Gloria V., King, Peter, Si, Ying, Kwon, Yuri, Batthyány, Carlos, Barbeito, Luis, Trias, Emiliano

“…Motor neuron degeneration and neuroinflammation are the most striking pathological features of amyotrophic lateral sclerosis (ALS). ALS currently has no cure…”
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A Focused Library of NO‐Donor Compounds with Potent Antiproliferative Activity Based on Green Multicomponent Reactions by Ingold, Mariana, Colella, Lucía, Hernández, Paola, Batthyány, Carlos, Tejedor, David, Puerta, Adrián, García‐Tellado, Fernando, Padrón, José M., Porcal, Williams, López, Gloria. V.

“…Cancer is the second leading cause of death worldwide. Herein, a strategy to quickly and efficiently identify novel lead compounds to develop anticancer…”
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New Nitric Oxide-Releasing Compounds as Promising Anti-Bladder Cancer Drugs by Varela, María, López, Miriam, Ingold, Mariana, Alem, Diego, Perini, Valentina, Perelmuter, Karen, Bollati-Fogolín, Mariela, López, Gloria V, Hernández, Paola

“…Bladder cancer is a worldwide problem and improved therapies are urgently needed. In the search for newer strong antitumor compounds, herein, we present the…”
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Macrophage activation induces formation of the anti-inflammatory lipid cholesteryl-nitrolinoleate by Ferreira, Ana M, Ferrari, Mariana I, Trostchansky, Andrés, Batthyany, Carlos, Souza, José M, Alvarez, María N, López, Gloria V, Baker, Paul R S, Schopfer, Francisco J, O'Donnell, Valerie, Freeman, Bruce A, Rubbo, Homero

“…Nitroalkene derivatives of fatty acids act as adaptive, anti-inflammatory signalling mediators, based on their high-affinity PPARgamma…”
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Identification of thioredoxin glutathione reductase inhibitors that kill cestode and trematode parasites by Ross, Fabiana, Hernández, Paola, Porcal, Williams, López, Gloria V, Cerecetto, Hugo, González, Mercedes, Basika, Tatiana, Carmona, Carlos, Fló, Martín, Maggioli, Gabriela, Bonilla, Mariana, Gladyshev, Vadim N, Boiani, Mariana, Salinas, Gustavo

“…Parasitic flatworms are responsible for serious infectious diseases that affect humans as well as livestock animals in vast regions of the world. Yet, the drug…”
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