Search Results - "Lopez, Emma Muiños"

Age-related inflammation triggers skeletal stem/progenitor cell dysfunction by Josephson, Anne Marie, Bradaschia-Correa, Vivian, Lee, Sooyeon, Leclerc, Kevin, Patel, Karan S., Lopez, Emma Muinos, Litwa, Hannah P., Neibart, Shane S., Kadiyala, Manasa, Wong, Madeleine Z., Mizrahi, Matthew M., Yim, Nury L., Ramme, Austin J., Egol, Kenneth A., Leucht, Philipp

“…Aging is associated with impaired tissue regeneration. Stem cell number and function have been identified as potential culprits. We first demonstrate a direct…”
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Tissue Mimicry in Morphology and Composition Promotes Hierarchical Matrix Remodeling of Invading Stem Cells in Osteochondral and Meniscus Scaffolds by Stuckensen, Kai, Schwab, Andrea, Knauer, Markus, Muiños‐López, Emma, Ehlicke, Franziska, Reboredo, Jenny, Granero‐Moltó, Froilán, Gbureck, Uwe, Prósper, Felipe, Walles, Heike, Groll, Jürgen

“…An integral approach toward in situ tissue engineering through scaffolds that mimic tissue with regard to both tissue architecture and biochemical composition…”
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Hox genes are crucial regulators of periosteal stem cell identity by Leclerc, Kevin, Remark, Lindsey H, Ramsukh, Malissa, Josephson, Anne Marie, Palma, Laura, Parente, Paulo E L, Sambon, Margaux, Lee, Sooyeon, Lopez, Emma Muiños, Morgani, Sophie M, Leucht, Philipp

“…Periosteal stem and progenitor cells (PSPCs) are major contributors to bone maintenance and repair. Deciphering the molecular mechanisms that regulate their…”
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Molecular and Cellular Mechanisms of Delayed Fracture Healing in Mmp10 (Stromelysin 2) Knockout Mice by Valdés‐Fernández, José, López‐Martínez, Tania, Ripalda‐Cemboráin, Purificación, Calvo, Isabel A, Sáez, Borja, Romero‐Torrecilla, Juan Antonio, Aldazabal, Javier, Muiños‐López, Emma, Montiel, Verónica, Orbe, Josune, Rodríguez, José Antonio, Páramo, José Antonio, Prósper, Felipe, Granero‐Moltó, Froilán

“…ABSTRACT The remodeling of the extracellular matrix is a central function in endochondral ossification and bone homeostasis. During secondary fracture healing,…”
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Characterization of microRNA expression profiles in normal and osteoarthritic human chondrocytes by Díaz-Prado, Silvia, Cicione, Claudia, Muiños-López, Emma, Hermida-Gómez, Tamara, Oreiro, Natividad, Fernández-López, Carlos, Blanco, Francisco J

“…Osteoarthritis (OA) is a multifactorial disease characterized by destruction of the articular cartilage due to environmental, mechanical and genetic…”
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Multilineage differentiation potential of cells isolated from the human amniotic membrane by Díaz-Prado, Silvia, Muiños-López, Emma, Hermida-Gómez, Tamara, Rendal-Vázquez, Maria Esther, Fuentes-Boquete, Isaac, de Toro, Francisco J., Blanco, Francisco J.

“…The human amniotic membrane (HAM) contains two cell types from different embryological origins. Human amnion epithelial cells (hAECs) are derived from the…”
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Combination of Intra-Articular and Intraosseous Injections of Platelet Rich Plasma for Severe Knee Osteoarthritis: A Pilot Study by Azofra, Juan, Padilla, Sabino, Fiz, Nicolás, Pompei, Orlando, Prósper, Felipe, Granero-Moltó, Froilán, Paiva, Bruno, Muiños-López, Emma, Sánchez, Pello, Delgado, Diego, Sánchez, Mikel, Pérez, Juan Carlos

“…The aim of this study was to assess a novel approach to treating severe knee osteoarthritis by targeting synovial membrane, superficial articular cartilage,…”
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Autologous bioscaffolds based on different concentrations of platelet rich plasma and synovial fluid as a vehicle for mesenchymal stem cells by Garate, Ane, Sánchez, Pello, Delgado, Diego, Bilbao, Ane Miren, Muiños‐López, Emma, Granero‐Moltó, Froilán, Orive, Gorka, Prosper, Felipe, Pedraz, José Luis, Sánchez, Mikel

“…In the field of tissue engineering, diverse types of bioscaffolds are being developed currently for osteochondral defect applications. In this work, a novel…”
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Human amniotic membrane as an alternative source of stem cells for regenerative medicine by Díaz-Prado, Silvia, Muiños-López, Emma, Hermida-Gómez, Tamara, Cicione, Claudia, Rendal-Vázquez, M. Esther, Fuentes-Boquete, Isaac, de Toro, Francisco J., Blanco, Francisco J.

“…The human amniotic membrane (HAM) is a highly abundant and readily available tissue. This amniotic tissue has considerable advantageous characteristics to be…”
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Periosteum‐derived mesenchymal progenitor cells in engineered implants promote fracture healing in a critical‐size defect rat model by González‐Gil, Ana B., Lamo‐Espinosa, José M., Muiños‐López, Emma, Ripalda‐Cemboráin, Purificación, Abizanda, Gloria, Valdés‐Fernández, José, López‐Martínez, Tania, Flandes‐Iparraguirre, María, Andreu, Ion, Elizalde, María Reyes, Stuckensen, Kai, Groll, Jürgen, De‐Juan‐Pardo, Elena M., Prósper, Felipe, Granero‐Moltó, Froilán

“…An attractive alternative to bone autografts is the use of autologous mesenchymal progenitor cells (MSCs) in combination with biomaterials. We compared the…”
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Quantification of Cells Expressing Mesenchymal Stem Cell Markers in Healthy and Osteoarthritic Synovial Membranes by HERMIDA-GOMEZ, Tamara, FUENTES-BOQUETE, Isaac, GIMENO-LONGAS, Maria José, MUINOS-LOPEZ, Emma, DIAZ-PRADO, Silvia, DE TORO, Francisco Javier, BLANCO, Francisco Javier

“…To quantify cells expressing mesenchymal stem cell (MSC) markers in synovial membranes from human osteoarthritic (OA) and healthy joints. Synovial membranes…”
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Novel hybrid biocomposites for tendon grafts: The addition of silk to polydioxanone and poly(lactide-co-caprolactone) enhances material properties, in vitro and in vivo biocompatibility by Shiroud Heidari, Behzad, Muiños Lopez, Emma, Harrington, Emma, Ruan, Rui, Chen, Peilin, Davachi, Seyed Mohammad, Allardyce, Benjamin, Rajkhowa, Rangam, Dilley, Rodney, Granero-Moltó, Froilán, De-Juan-Pardo, Elena M., Zheng, Minghao, Doyle, Barry

“…Biopolymers play a critical role as scaffolds used in tendon and ligament (TL) regeneration. Although advanced biopolymer materials have been proposed with…”
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Effects of Severe Hypoxia on Bone Marrow Mesenchymal Stem Cells Differentiation Potential by Cicione, Claudia, Muiños-López, Emma, Hermida-Gómez, Tamara, Fuentes-Boquete, Isaac, Díaz-Prado, Silvia, Blanco, Francisco J.

“…Background. The interests in mesenchymal stem cells (MSCs) and their application in cell therapy have resulted in a better understanding of the basic biology…”
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An engineered periosteum for efficient delivery of rhBMP-2 and mesenchymal progenitor cells during bone regeneration by Romero-Torrecilla, Juan Antonio, Lamo-Espinosa, José María, Ripalda-Cemboráin, Purificación, López-Martínez, Tania, Abizanda, Gloria, Riera-Álvarez, Luis, de Galarreta-Moriones, Sergio Ruiz, López-Barberena, Asier, Rodríguez-Flórez, Naiara, Elizalde, Reyes, Jayawarna, Vineetha, Valdés-Fernández, José, de Anleo, Miguel Echanove-González, Childs, Peter, de Juan-Pardo, Elena, Salmeron-Sanchez, Manuel, Prósper, Felipe, Muiños-López, Emma, Granero-Moltó, Froilán

“…During bone regeneration, the periosteum acts as a carrier for key regenerative cues, delivering osteochondroprogenitor cells and crucial growth factors to the…”
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Modulation of Synovial Fluid-Derived Mesenchymal Stem Cells by Intra-Articular and Intraosseous Platelet Rich Plasma Administration by Muiños-López, Emma, Delgado, Diego, Sánchez, Pello, Paiva, Bruno, Anitua, Eduardo, Fiz, Nicolás, Aizpurua, Beatriz, Guadilla, Jorge, Padilla, Sabino, Granero-Moltó, Froilán, Prósper, Felipe, Sánchez, Mikel

“…The aim of this study was to evaluate the effect of intra-articular (IA) or a combination of intra-articular and intraosseous (IO) infiltration of Platelet…”
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Potential use of the human amniotic membrane as a scaffold in human articular cartilage repair by Díaz-Prado, Silvia, Rendal-Vázquez, Mª Esther, Muiños-López, Emma, Hermida-Gómez, Tamara, Rodríguez-Cabarcos, Margarita, Fuentes-Boquete, Isaac, de Toro, Francisco J., Blanco, Francisco J.

“…The human amniotic membrane (HAM) is an abundant and readily obtained tissue that may be an important source of scaffold for transplanted chondrocytes in…”
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Systemic NF-κB-mediated inflammation promotes an aging phenotype in skeletal stem/progenitor cells by Josephson, Anne Marie, Leclerc, Kevin, Remark, Lindsey H, Lopeź, Emma Muiños, Leucht, Philipp

“…Aging tissues undergo a progressive decline in regenerative potential. This decline in regenerative responsiveness has been attributed to changes in…”
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Non-psychoactive Cannabidiol Prevents Osteoporosis in an Animal Model and Increases Cell Viability, Proliferation, and Osteogenic Gene Expression in Human Skeletal Stem and Progenitor Cells by Ihejirika-Lomedico, Rivka, Patel, Karan, Buchalter, Daniel B, Kirby, David J, Mehta, Devan, Dankert, John F, Muiños-López, Emma, Ihejirika, Yael, Leucht, Philipp

“…Cannabidiol (CBD), the non-psychoactive component of the Cannabis sativa plant, is marketed as a potential therapeutic agent and has been studied for its roles…”
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Modulating the systemic and local adaptive immune response after fracture improves bone regeneration during aging by Lopez, Emma Muiños, Leclerc, Kevin, Ramsukh, Malissa, Parente, Paulo EL, Patel, Karan, Aranda, Carlos J., Josephson, Anna M., Remark, Lindsey H., Kirby, David J., Buchalter, Daniel B., Hadi, Tarik, Morgani, Sophie M., Ramkhelawon, Bhama, Leucht, Philipp

“…Tissue injury leads to the well-orchestrated mobilization of systemic and local innate and adaptive immune cells. During aging, immune cell recruitment is…”
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Human Amniotic Mesenchymal Stromal Cells as Favorable Source for Cartilage Repair by Muiños-López, Emma, Hermida-Gómez, Tamara, Fuentes-Boquete, Isaac, de Toro-Santos, Javier, Blanco, Francisco Javier, Díaz-Prado, Silvia María

“…Localized trauma-derived breakdown of the hyaline articular cartilage may progress toward osteoarthritis, a degenerative condition characterized by total loss…”
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