Search Results - "Lopez, Diana C"
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Nonlinear ill-posed problem analysis in model-based parameter estimation and experimental design
Published in Computers & chemical engineering (09-06-2015)“…•We discuss nonlinear ill-posed problems in parameter estimation and experiment design.•Identifiability is analyzed by the singular value spectrum of the…”
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Modelling overflow metabolism in Escherichia coli by acetate cycling
Published in Biochemical engineering journal (15-09-2017)“…•A model of acetate production and overflow metabolism in E. coli was developed.•The model was fitted to data from fed-batch culture of E. coli.•The fitted…”
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Durability and Performance of 2298 Trifecta Aortic Valve Prostheses: A Propensity-Matched Analysis
Published in The Annals of thoracic surgery (01-04-2021)“…Reports of early failure of the Trifecta externally wrapped, bovine pericardial aortic valve prosthesis (Abbott Laboratories, Abbott Park, IL) raise concerns…”
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Output uncertainty of dynamic growth models: Effect of uncertain parameter estimates on model reliability
Published in Biochemical engineering journal (15-10-2019)“…•A framework for uncertainty analysis of biokinetic models is presented.•Parameter identifiability is deduced from the dynamic sensitivity matrix.•A…”
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Experimental evaluation of an approach to online redesign of experiments for parameter determination
Published in AIChE journal (01-06-2013)“…The online redesign of experiments for parameter determination of nonlinear dynamic systems has been studied recently by different research groups. In this…”
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Augmentation of tumor expression of HLA-DR, CXCL9, and CXCL10 may improve olfactory neuroblastoma immunotherapeutic responses
Published in Journal of translational medicine (31-05-2024)“…Olfactory neuroblastoma is a rare malignancy of the anterior skull base typically treated with surgery and adjuvant radiation. Although outcomes are fair for…”
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An algorithm for the identification and estimation of relevant parameters for optimization under uncertainty
Published in Computers & chemical engineering (04-12-2014)“…[Display omitted] •Strategies from parameter estimation and objective function analysis are combined.•A systematic algorithm for identifying relevant uncertain…”
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Real-time adaptive input design for the determination of competitive adsorption isotherms in liquid chromatography
Published in Computers & chemical engineering (02-11-2016)“…•We present experimental results for the real-time adaptive optimal input design for parameter estimation.•We discuss numeric regularization strategies for…”
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Multi-spectral immunofluorescence evaluation of the myeloid, T cell, and natural killer cell tumor immune microenvironment in chordoma may guide immunotherapeutic strategies
Published in Frontiers in oncology (21-10-2022)“…Background Chordoma is a rare, invasive, and devastating bone malignancy of residual notochord tissue that arises at the skull base, sacrum, or spine. In order…”
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Chordoma cancer stem cell subpopulation characterization may guide targeted immunotherapy approaches to reduce disease recurrence
Published in Frontiers in oncology (29-04-2024)“…Cancer stem cells (CSCs), a group of tumor-initiating and tumor-maintaining cells, may be major players in the treatment resistance and recurrence distinctive…”
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Exploiting the immunogenic potential of standard of care radiation or cisplatin therapy in preclinical models of HPV-associated malignancies
Published in Journal for immunotherapy of cancer (01-12-2022)“…While radiation and chemotherapy are primarily purposed for their cytotoxic effects, a growing body of preclinical and clinical evidence demonstrates an…”
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Experimental Analysis and Numerical Modeling of a Shell and Tube Heat Storage Unit with Phase Change Materials
Published in Industrial & engineering chemistry research (27-07-2016)“…Thermal storages are part of highly integrated energy systems. The development of accurate and reduced models is critical for efficient simulations on a…”
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Evolution and characteristics of studies estimating attributable mortality to second-hand smoke: a systematic review
Published in European journal of public health (26-03-2024)“…Several studies have estimated the impact of second-hand smoke (SHS) exposure on mortality in the population of different countries. This study aimed to…”
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Large whale entanglements in Mexico, a 25‐year review from 1996 to 2021
Published in Marine mammal science (01-07-2024)“…Large whale entanglements are considered a significant threat to populations on a global scale. In the Mexican Pacific and Baja California Peninsula…”
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Triphasic response after endoscopic craniopharyngioma resection and its dependency on infundibular preservation or sacrifice
Published in Journal of neurosurgery (01-09-2023)“…Surgery is the primary treatment for craniopharyngioma with the preservation of hypothalamic function of paramount importance. Infundibular preservation is…”
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Emerging concepts in sinonasal tumor research
Published in Current opinion in otolaryngology & head and neck surgery (01-02-2022)“…Sinonasal malignancies are rare and understudied, often diagnosed at late stages, and may behave aggressively. This review explores investigative diagnostic,…”
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A Computational Framework for Identifiability and Ill-Conditioning Analysis of Lithium-Ion Battery Models
Published in Industrial & engineering chemistry research (23-03-2016)“…The lack of informative experimental data and the complexity of first-principles battery models make the recovery of kinetic, transport, and thermodynamic…”
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Model-based identifiable parameter determination applied to a simultaneous saccharification and fermentation process model for bio-ethanol production
Published in Biotechnology progress (01-07-2013)“…In this work, a methodology for the model‐based identifiable parameter determination (MBIPD) is presented. This systematic approach is proposed to be used for…”
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Optimization Model of Crude Oil Distillation Units for Optimal Crude Oil Blending and Operating Conditions
Published in Industrial & engineering chemistry research (11-09-2013)“…This work presents the mathematical formulation of a nonlinear programming (NLP) model which optimizes simultaneously crude oil blending and operating…”
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