Search Results - "Lopez, Colleen A."
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Physiological and pharmacological stimulation for in vitro maturation of substrate metabolism in human induced pluripotent stem cell-derived cardiomyocytes
Published in Scientific reports (08-04-2021)“…Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) enable human cardiac cells to be studied in vitro, although they use glucose as their…”
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Changing Metabolism in Differentiating Cardiac Progenitor Cells-Can Stem Cells Become Metabolically Flexible Cardiomyocytes?
Published in Frontiers in cardiovascular medicine (19-09-2018)“…The heart is a metabolic omnivore and the adult heart selects the substrate best suited for each circumstance, with fatty acid oxidation preferred in order to…”
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Metabolic flux analyses to assess the differentiation of adult cardiac progenitors after fatty acid supplementation
Published in Stem cell research (01-07-2019)“…Myocardial infarction is the most prevalent of cardiovascular diseases and pharmacological interventions do not lead to restoration of the lost cardiomyocytes…”
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De Novo Elastin Assembly Alleviates Development of Supravalvular Aortic Stenosis-Brief Report
Published in Arteriosclerosis, thrombosis, and vascular biology (01-07-2024)“…A series of incurable cardiovascular disorders arise due to improper formation of elastin during development. Supravalvular aortic stenosis (SVAS), resulting…”
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Epigallocatechin gallate facilitates extracellular elastin fiber formation in induced pluripotent stem cell derived vascular smooth muscle cells for tissue engineering
Published in Journal of molecular and cellular cardiology (01-02-2022)“…Tissue engineered vascular grafts possess several advantages over synthetic or autologous grafts, including increased availability and reduced rates of…”
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Modular design of a tissue engineered pulsatile conduit using human induced pluripotent stem cell-derived cardiomyocytes
Published in Acta biomaterialia (15-01-2020)“…Single ventricle heart defects (SVDs) are congenital disorders that result in a variety of complications, including increased ventricular mechanical strain and…”
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Modular design of a tissue engineered pulsatile conduit using human induced pluripotent stem cell-derived cardiomyocytes
Published in Acta biomaterialia (15-01-2020)Get full text
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