Search Results - "Lopez, Alexandre"
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An overview of in vitro 3D models of the blood-brain barrier as a tool to predict the in vivo permeability of nanomedicines
Published in Advanced drug delivery reviews (01-05-2023)“…[Display omitted] The blood–brain barrier (BBB) prevents efficient drug delivery to the central nervous system. As a result, brain diseases remain one of the…”
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Embolization therapy with microspheres for the treatment of liver cancer: State-of-the-art of clinical translation
Published in Acta biomaterialia (01-09-2022)“…Embolization with microspheres is a therapeutic strategy based on the selective occlusion of the blood vessels feeding a tumor. This procedure is…”
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Latest advances in glucose-responsive microneedle-based systems for transdermal insulin delivery
Published in International journal of biological macromolecules (01-04-2024)“…The development of a self-regulated minimally invasive system for insulin delivery can be considered as the holy grail in the field of diabetes mellitus. A…”
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Bedside POCUS during ward emergencies is associated with improved diagnosis and outcome: an observational, prospective, controlled study
Published in Critical care (London, England) (22-01-2021)“…Rapid response teams are intended to improve early diagnosis and intervention in ward patients who develop acute respiratory or circulatory failure. A…”
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A Granulocytic Signature Identifies COVID-19 and Its Severity
Published in The Journal of infectious diseases (15-12-2020)“…Abstract Background An unbiased approach to SARS-CoV-2–induced immune dysregulation has not been undertaken so far. We aimed to identify previously unreported…”
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Perceptions regarding open science appraised by editors of scholarly publications published in Spain
Published in Learned publishing (01-04-2023)“…Pillars of open science are often included within the editorial policies of scholarly journals, including policies on open access publication, availability of…”
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Glycocalyx Preservation and NO Production in Fatty Livers-The Protective Role of High Molecular Polyethylene Glycol in Cold Ischemia Injury
Published in International journal of molecular sciences (12-08-2018)“…Improving the protection of marginal liver grafts during static cold storage is a major hurdle to increase the donor pool of organs. The endothelium glycocalyx…”
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A Novel Oxygen Carrier (M101) Attenuates Ischemia-Reperfusion Injuries during Static Cold Storage in Steatotic Livers
Published in International journal of molecular sciences (09-08-2021)“…The combined impact of an increasing demand for liver transplantation and a growing incidence of nonalcoholic liver disease has provided the impetus for the…”
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Anti-cardiolipin IgG autoantibodies associate with circulating extracellular DNA in severe COVID-19
Published in Scientific reports (22-07-2022)“…Whereas the detection of antiphospholipid autoantibodies (aPL) in COVID-19 is of increasing interest, their role is still unclear. We analyzed a large aPL…”
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Left ventricular longitudinal strain variations assessed by speckle-tracking echocardiography after a passive leg raising maneuver in patients with acute circulatory failure to predict fluid responsiveness: A prospective, observational study
Published in PloS one (30-09-2021)“…Background An association was reported between the left ventricular longitudinal strain (LV-LS) and preload. LV-LS reflects the left cardiac function curve as…”
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Impact of dexamethasone on the incidence of ventilator-associated pneumonia and blood stream infections in COVID-19 patients requiring invasive mechanical ventilation: a multicenter retrospective study
Published in Annals of intensive care (31-05-2021)“…Background Dexamethasone decreases mortality in patients with severe coronavirus disease 2019 (COVID-19) and has become the standard of care during the second…”
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Association between mortality and highly antimicrobial-resistant bacteria in intensive care unit-acquired pneumonia
Published in Scientific reports (13-08-2021)“…Data on the relationship between antimicrobial resistance and mortality remain scarce, and this relationship needs to be investigated in intensive care units…”
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Comparison of two-drug combinations, amikacin/tigecycline/imipenem and amikacin/tigecycline/clarithromycin against Mycobacteroides abscessus subsp. abscessus using the in vitro time-kill assay
Published in Journal of antibiotics (01-04-2021)“…Nontuberculous mycobacteria include 198 mycobacterial species. Among these, Mycobacteroides abscessus is a rapidly growing mycobacteria that causes lung and…”
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Impact of Sex Hormones on Macrophage Responses to Coxiella burnetii
Published in Frontiers in immunology (20-12-2021)“…Q fever, a zoonosis caused by , affects more males than females despite a similar level of exposure. A protective role of estradiol has been reported in mice,…”
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Polyethylene glycols: An effective strategy for limiting liver ischemia reperfusion injury
Published in World journal of gastroenterology : WJG (28-07-2016)“…Liver ischemia-reperfusion injury(IRI) is an inherent feature of liver surgery and liver transplantation in which damage to a hypoxic organ(ischemia) is…”
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Timeline of Translational Formulation Technologies for Cancer Therapy: Successes, Failures, and Lessons Learned Therefrom
Published in Pharmaceutics (28-10-2020)“…Over the past few decades, the field of cancer therapy has seen a significant change in the way in which formulations are designed and developed, resulting in…”
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Relevance of Endoplasmic Reticulum Stress Cell Signaling in Liver Cold Ischemia Reperfusion Injury
Published in International journal of molecular sciences (01-06-2016)“…The endoplasmic reticulum (ER) is involved in calcium homeostasis, protein folding and lipid biosynthesis. Perturbations in its normal functions lead to a…”
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Aldehyde Dehydrogenase 2 (ALDH2) in Rat Fatty Liver Cold Ischemia Injury
Published in International journal of molecular sciences (22-08-2018)“…Institut George Lopez-1 (IGL-1) and Histidine-tryptophan-ketoglutarate (HTK) solutions are proposed as alternatives to UW (gold standard) in liver…”
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The challenges facing library and information science journals: Editors' opinions
Published in Learned publishing (01-04-2016)“…This study aimed to gather the opinions of editors of Library and Information Science journals indexed in Scopus and the Web of Knowledge regarding the current…”
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Scientific output in library and information science: A comparative study of the journals Anales de Documentación and BiD textos universitaris en biblioteconomia i documentació
Published in Journal of librarianship and information science (01-06-2019)“…In recent years, academic journals have evolved to become a vehicle for scientific communication that is acknowledged by the official organizations that…”
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