Search Results - "Lopes, Tiago J. S."

Syrian hamsters as a small animal model for SARS-CoV-2 infection and countermeasure development by Imai, Masaki, Iwatsuki-Horimoto, Kiyoko, Hatta, Masato, Loeber, Samantha, Halfmann, Peter J., Nakajima, Noriko, Watanabe, Tokiko, Ujie, Michiko, Takahashi, Kenta, Ito, Mutsumi, Yamada, Shinya, Fan, Shufang, Chiba, Shiho, Kuroda, Makoto, Guan, Lizheng, Takada, Kosuke, Armbrust, Tammy, Balogh, Aaron, Furusawa, Yuri, Okuda, Moe, Ueki, Hiroshi, Yasuhara, Atsuhiro, Sakai-Tagawa, Yuko, Lopes, Tiago J. S., Kiso, Maki, Yamayoshi, Seiya, Kinoshita, Noriko, Ohmagari, Norio, Hattori, Shin-ichiro, Takeda, Makoto, Mitsuya, Hiroaki, Krammer, Florian, Suzuki, Tadaki, Kawaoka, Yoshihiro

“…At the end of 2019, a novel coronavirus (severe acute respiratory syndrome coronavirus 2; SARS-CoV-2) was detected in Wuhan, China, that spread rapidly around…”
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Full-scale network analysis reveals properties of the FV protein structure organization by Ferreira-Martins, André J., Castaldoni, Rodrigo, Alencar, Brenno M., Ferreira, Marcos V., Nogueira, Tatiane, Rios, Ricardo A., Lopes, Tiago J. S.

“…Blood coagulation is a vital process for humans and other species. Following an injury to a blood vessel, a cascade of molecular signals is transmitted,…”
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Integrating Transcriptomic and Proteomic Data Using Predictive Regulatory Network Models of Host Response to Pathogens by Chasman, Deborah, Walters, Kevin B, Lopes, Tiago J S, Eisfeld, Amie J, Kawaoka, Yoshihiro, Roy, Sushmita

“…Mammalian host response to pathogenic infections is controlled by a complex regulatory network connecting regulatory proteins such as transcription factors and…”
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Enhancing diagnostic accuracy of multiple myeloma through ML-driven analysis of hematological slides: new dataset and identification model to support hematologists by Andrade, Caio L. B., Ferreira, Marcos V., Alencar, Brenno M., Junior, Ariel M. A., Lopes, Tiago J. S., dos Santos, Allan S., dos Santos, Mariane M., Silva, Maria I. C. S., Rosa, Izabela M. D. R. P., Filho, Jorge L. S. B., Guimaraes, Matheus A., de Carvalho, Gilson C., Santos, Herbert H. M., Santos, Márcia M. L., Meyer, Roberto, Rios, Tatiane N., Rios, Ricardo A., Freire, Songeli M.

“…Multiple Myeloma (MM) is a hematological malignancy characterized by the clonal proliferation of plasma cells within the bone marrow. Diagnosing MM presents…”
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Adding protein context to the human protein-protein interaction network to reveal meaningful interactions by Schaefer, Martin H, Lopes, Tiago J S, Mah, Nancy, Shoemaker, Jason E, Matsuoka, Yukiko, Fontaine, Jean-Fred, Louis-Jeune, Caroline, Eisfeld, Amie J, Neumann, Gabriele, Perez-Iratxeta, Carol, Kawaoka, Yoshihiro, Kitano, Hiroaki, Andrade-Navarro, Miguel A

“…Interactions of proteins regulate signaling, catalysis, gene expression and many other cellular functions. Therefore, characterizing the entire human…”
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Development of high-yield influenza B virus vaccine viruses by Ping, Jihui, Lopes, Tiago J. S., Neumann, Gabriele, Kawaoka, Yoshihiro

“…The burden of human infections with influenza A and B viruses is substantial, and the impact of influenza B virus infections can exceed that of influenza A…”
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Development of an Enhanced High-Yield Influenza Vaccine Backbone in Embryonated Chicken Eggs by Guan, Lizheng, Ping, Jihui, Lopes, Tiago J. S, Fan, Shufang, Presler, Robert, Neumann, Gabriele, Kawaoka, Yoshihiro

“…Vaccination is an efficient approach to preventing influenza virus infections. Recently, we developed influenza A and B virus vaccine backbones that increased…”
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Tissue-specific subnetworks and characteristics of publicly available human protein interaction databases by LOPES, Tiago J. S, SCHAEFER, Martin, SHOEMAKER, Jason, MATSUOKA, Yukiko, FONTAINE, Jean-Fred, NEUMANN, Gabriele, ANDRADE-NAVARRO, Miguel A, KAWAOKA, Yoshihiro, KITANO, Hiroaki

“…Protein-protein interaction (PPI) databases are widely used tools to study cellular pathways and networks; however, there are several databases available that…”
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CTen: a web-based platform for identifying enriched cell types from heterogeneous microarray data by Shoemaker, Jason E, Lopes, Tiago J S, Ghosh, Samik, Matsuoka, Yukiko, Kawaoka, Yoshihiro, Kitano, Hiroaki

“…Interpreting in vivo sampled microarray data is often complicated by changes in the cell population demographics. To put gene expression into its proper…”
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A comprehensive map of the influenza A virus replication cycle by Matsuoka, Yukiko, Matsumae, Hiromi, Katoh, Manami, Eisfeld, Amie J, Neumann, Gabriele, Hase, Takeshi, Ghosh, Samik, Shoemaker, Jason E, Lopes, Tiago J S, Watanabe, Tokiko, Watanabe, Shinji, Fukuyama, Satoshi, Kitano, Hiroaki, Kawaoka, Yoshihiro

“…Influenza is a common infectious disease caused by influenza viruses. Annual epidemics cause severe illnesses, deaths, and economic loss around the world. To…”
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Molecular Determinants of Virulence and Stability of a Reporter-Expressing H5N1 Influenza A Virus by Zhao, Dongming, Fukuyama, Satoshi, Yamada, Shinya, Lopes, Tiago J S, Maemura, Tadashi, Katsura, Hiroaki, Ozawa, Makoto, Watanabe, Shinji, Neumann, Gabriele, Kawaoka, Yoshihiro

“…We previously reported that an H5N1 virus carrying the Venus reporter gene, which was inserted into the NS gene segment from the A/Puerto Rico/8/1934(H1N1)…”
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Characterization of a new SARS-CoV-2 variant that emerged in Brazil by Imai, Masaki, Halfmann, Peter J., Yamayoshi, Seiya, Iwatsuki-Horimoto, Kiyoko, Chiba, Shiho, Watanabe, Tokiko, Nakajima, Noriko, Ito, Mutsumi, Kuroda, Makoto, Kiso, Maki, Maemura, Tadashi, Takahashi, Kenta, Loeber, Samantha, Hatta, Masato, Koga, Michiko, Nagai, Hiroyuki, Yamamoto, Shinya, Saito, Makoto, Adachi, Eisuke, Akasaka, Osamu, Nakamura, Morio, Nakachi, Ichiro, Ogura, Takayuki, Baba, Rie, Fujita, Kensuke, Ochi, Junichi, Mitamura, Keiko, Kato, Hideaki, Nakajima, Hideaki, Yagi, Kazuma, Hattori, Shin-ichiro, Maeda, Kenji, Suzuki, Tetsuya, Miyazato, Yusuke, Valdez, Riccardo, Gherasim, Carmen, Furusawa, Yuri, Okuda, Moe, Ujie, Michiko, Lopes, Tiago J. S., Yasuhara, Atsuhiro, Ueki, Hiroshi, Sakai-Tagawa, Yuko, Eisfeld, Amie J., Baczenas, John J., Baker, David A., O’Connor, Shelby L., O’Connor, David H., Fukushi, Shuetsu, Fujimoto, Tsuguto, Kuroda, Yudai, Gordon, Aubree, Maeda, Ken, Ohmagari, Norio, Sugaya, Norio, Yotsuyanagi, Hiroshi, Mitsuya, Hiroaki, Suzuki, Tadaki, Kawaoka, Yoshihiro

“…The spike (S) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) plays a key role in viral infectivity. It is also the major antigen…”
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Identification of interferon-stimulated genes that attenuate Ebola virus infection by Kuroda, Makoto, Halfmann, Peter J., Hill-Batorski, Lindsay, Ozawa, Makoto, Lopes, Tiago J. S., Neumann, Gabriele, Schoggins, John W., Rice, Charles M., Kawaoka, Yoshihiro

“…The West Africa Ebola outbreak was the largest outbreak ever recorded, with over 28,000 reported infections; this devastating epidemic emphasized the need to…”
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Protein residue network analysis reveals fundamental properties of the human coagulation factor VIII by Lopes, Tiago J. S., Rios, Ricardo, Nogueira, Tatiane, Mello, Rodrigo F.

“…Hemophilia A is an X-linked inherited blood coagulation disorder caused by the production and circulation of defective coagulation factor VIII protein. People…”
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Identification of mammalian-adapting mutations in the polymerase complex of an avian H5N1 influenza virus by Taft, Andrew S., Ozawa, Makoto, Fitch, Adam, Depasse, Jay V., Halfmann, Peter J., Hill-Batorski, Lindsay, Hatta, Masato, Friedrich, Thomas C., Lopes, Tiago J. S., Maher, Eileen A., Ghedin, Elodie, Macken, Catherine A., Neumann, Gabriele, Kawaoka, Yoshihiro

“…Avian influenza viruses of the H5N1 subtype pose a serious global health threat due to the high mortality (>60%) associated with the disease caused by these…”
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Mutations in the PA Protein of Avian H5N1 Influenza Viruses Affect Polymerase Activity and Mouse Virulence by Zhong, Gongxun, Le, Mai Quynh, Lopes, Tiago J S, Halfmann, Peter, Hatta, Masato, Fan, Shufang, Neumann, Gabriele, Kawaoka, Yoshihiro

“…To study the influenza virus determinants of pathogenicity, we characterized two highly pathogenic avian H5N1 influenza viruses isolated in Vietnam in 2012…”
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Country transition index based on hierarchical clustering to predict next COVID-19 waves by Rios, Ricardo A., Nogueira, Tatiane, Coimbra, Danilo B., Lopes, Tiago J. S., Abraham, Ajith, Mello, Rodrigo F. de

“…COVID-19 has widely spread around the world, impacting the health systems of several countries in addition to the collateral damage that societies will face in…”
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Mutations in the Neuraminidase-Like Protein of Bat Influenza H18N11 Virus Enhance Virus Replication in Mammalian Cells, Mice, and Ferrets by Zhong, Gongxun, Fan, Shufang, Hatta, Masato, Nakatsu, Sumiho, Walters, Kevin B, Lopes, Tiago J S, Wang, Jessica I-Hsuan, Ozawa, Makoto, Karasin, Alexander, Li, Yan, Tong, Suxiang, Donis, Ruben O, Neumann, Gabriele, Kawaoka, Yoshihiro

“…To characterize bat influenza H18N11 virus, we propagated a reverse genetics-generated H18N11 virus in Madin-Darby canine kidney subclone II cells and detected…”
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Loss of Interleukin 1 Receptor Antagonist Enhances Susceptibility to Ebola Virus Infection by Hill-Batorski, Lindsay, Halfmann, Peter, Marzi, Andrea, Lopes, Tiago J. S., Neumann, Gabriele, Feldmann, Heinz, Kawaoka, Yoshihiro

“…The current outbreak of Ebola virus (EBOV) infection in West Africa is unprecedented, with nearly 26 000 confirmed cases and > 10 000 deaths. Comprehensive…”
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A Machine Learning Framework Predicts the Clinical Severity of Hemophilia B Caused by Point-Mutations by Lopes, Tiago J. S., Nogueira, Tatiane, Rios, Ricardo

“…Blood coagulation is a vital physiological mechanism to stop blood loss following an injury to a blood vessel. This process starts immediately upon damage to…”
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