Search Results - "Lopes, Rafael L"
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IL-10 is required for polarization of macrophages to M2-like phenotype by mycobacterial DnaK (heat shock protein 70)
Published in Cytokine (Philadelphia, Pa.) (01-09-2016)“…•DnaK-induced polarization of macrophages depends not only on IL-10 production, but also on IL-10 receptor signaling.•DnaK induces TGF-β mRNA transcription,…”
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March1-dependent modulation of donor MHC II on CD103+ dendritic cells mitigates alloimmunity
Published in Nature communications (28-08-2018)“…In transplantation, donor dendritic cells (do-DCs) initiate the alloimmune response either by direct interaction with host T cells or by transferring intact…”
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Extracellular mycobacterial DnaK polarizes macrophages to the M2-like phenotype
Published in PloS one (24-11-2014)“…Macrophages are myeloid cells that play an essential role in inflammation and host defense, regulating immune responses and maintaining tissue homeostasis…”
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Extracellular Hsp70 inhibits pro-inflammatory cytokine production by IL-10 driven down-regulation of C/EBPβ and C/EBPδ
Published in International journal of hyperthermia (01-08-2013)“…Extracellular Hsp70 has anti-inflammatory potential, demonstrated in different models of inflammatory diseases. We investigated probable mechanisms used by…”
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Modulation of Alloimmunity by Heat Shock Proteins
Published in Frontiers in immunology (09-08-2016)“…The immunological mechanisms that evolved for host defense against pathogens and injury are also responsible for transplant rejection. Host rejection of…”
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Extracellular Mycobacterial DnaK Polarizes Macrophages to the M2-Like Phenotype: e113441
Published in PloS one (01-11-2014)“…Macrophages are myeloid cells that play an essential role in inflammation and host defense, regulating immune responses and maintaining tissue homeostasis…”
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Journal Article