Search Results - "Lopes, Nair"
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A panel of intestinal differentiation markers (CDX2, GPA33, and LI-cadherin) identifies gastric cancer patients with favourable prognosis
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (01-09-2020)“…Background Gastric cancer is the fifth most common cancer and the third cause of global cancer mortality. CDX2 is an intestinal differentiation marker with…”
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2
Epigenetic Alterations in Oesophageal Cancer: Expression and Role of the Involved Enzymes
Published in International journal of molecular sciences (15-05-2020)“…Oesophageal cancer is a life-threatening disease, accounting for high mortality rates. The poor prognosis of this malignancy is mostly due to late diagnosis…”
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3
Alterations in Vitamin D signalling and metabolic pathways in breast cancer progression: a study of VDR, CYP27B1 and CYP24A1 expression in benign and malignant breast lesions Vitamin D pathways unbalanced in breast lesions
Published in BMC cancer (11-09-2010)“…Background Breast cancer is a heterogeneous disease associated with different patient prognosis and responses to therapy. Vitamin D has been emerging as a…”
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4
Hydralazine and Panobinostat Attenuate Malignant Properties of Prostate Cancer Cell Lines
Published in Pharmaceuticals (Basel, Switzerland) (13-07-2021)“…Among the well-established alterations contributing to prostate cancer (PCa) pathogenesis, epigenetics is an important player in its development and aggressive…”
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5
Anti-tumour activity of Panobinostat in oesophageal adenocarcinoma and squamous cell carcinoma cell lines
Published in Clinical epigenetics (03-08-2024)“…Oesophageal cancer remains a challenging disease with high mortality rates and few therapeutic options. In view of these difficulties, epigenetic drugs have…”
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6
Expression and Clinical Relevance of SOX9 in Gastric Cancer
Published in Disease markers (01-01-2019)“…Gastric cancer is one of the most frequent tumours and the third leading cause of cancer-related death worldwide. The investigation of new biomarkers that can…”
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7
Hydralazine and Enzalutamide: Synergistic Partners against Prostate Cancer
Published in Biomedicines (07-08-2021)“…Advanced prostate cancers frequently develop resistance to androgen-deprivation therapy with serious implications for patient survival. Considering their…”
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8
Molecular phenotypes of matched in situ and invasive components of breast carcinomas
Published in Human pathology (01-10-2011)“…Summary The current system of pathologic classification of human breast cancers does not take into account the biologic determinants of prognosis, nor is there…”
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Digital image analysis of multiplex fluorescence IHC in colorectal cancer recognizes the prognostic value of CDX2 and its negative correlation with SOX2
Published in Laboratory investigation (01-01-2020)“…Flourescence-based multiplex immunohistochemistry (mIHC) combined with multispectral imaging and digital image analysis (DIA) is a quantitative high-resolution…”
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Abstract 565: CDX2 targets, GPA33 and LI-cadherin, are novel biomarkers with prognostic value in gastric cancer
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Gastric cancer is one of the most common types of cancer and the third cause of cancer-related death worldwide. The aggressiveness of the disease is related…”
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11
Alterations in Vitamin D signalling and metabolic pathways in breast cancer progression: a study of VDR, CYP27B1 and CYP24A1 expression in benign and malignant breast lesions
Published in BMC cancer (11-09-2010)“…Breast cancer is a heterogeneous disease associated with different patient prognosis and responses to therapy. Vitamin D has been emerging as a potential…”
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12
Vitamin D and the mammary gland: a review on its role in normal development and breast cancer
Published in Breast cancer research : BCR (31-05-2012)“…Breast cancer is a heterogeneous disease associated with diverse biological behaviours and clinical outcome. Although some molecular subgroups of breast cancer…”
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Expression of FOXA1 and GATA-3 in breast cancer: the prognostic significance in hormone receptor-negative tumours
Published in Breast cancer research : BCR (01-01-2009)“…The expression of additional genes, other than oestrogen receptor (ER), may be important to the hormone-responsive phenotype of breast cancer. Microarray…”
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14
CD5 expression is regulated during human T‐cell activation by alternative polyadenylation, PTBP1, and miR‐204
Published in European journal of immunology (01-06-2016)“…T lymphocytes stimulated through their antigen receptor (TCR) preferentially express mRNA isoforms with shorter 3´ untranslated regions (3´‐UTRs) derived from…”
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15
A DNA methylation-based test for esophageal cancer detection
Published in Biomarker research (25-11-2020)“…Esophageal cancer (ECa) is the 7th most incident cancer and the 6th leading cause of cancer-related death. Most patients are diagnosed with locally advanced or…”
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16
P-cadherin and cytokeratin 5: useful adjunct markers to distinguish basal-like ductal carcinomas in situ
Published in Virchows Archiv : an international journal of pathology (01-01-2007)“…Gene expression profiles of invasive breast carcinomas have identified a subgroup of tumours with worse prognosis, which have been called "basal-like". These…”
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The basal epithelial marker P-cadherin associates with breast cancer cell populations harboring a glycolytic and acid-resistant phenotype
Published in BMC cancer (01-10-2014)“…Cancer stem cells are hypoxia-resistant and present a preponderant glycolytic metabolism. These characteristics are also found in basal-like breast carcinomas…”
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P-cadherin, vimentin and CK14 for identification of basal-like phenotype in breast carcinomas: an immunohistochemical study
Published in Histology and histopathology (01-08-2010)“…Introduction: The most suitable immunohistochemical criterion to identify basal-like breast carcinomas (BLBC), a molecular subgroup of breast cancer associated…”
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19
Vessel density assessed by endoglin expression in breast carcinomas with different expression profiles
Published in Histopathology (01-11-2009)“…Aims: To evaluate the relationship between microvessel density assessed by endoglin expression and the molecular subtypes of human invasive breast carcinomas…”
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Estudo de Implementação dos Ensaios Fotobiológicos da Iluminação LED
Published 01-01-2019“…A presente dissertação enquadra-se no âmbito do Mestrado em Engenharia Eletrotécnica – Sistemas Elétricos de Energia no Instituto Superior de Engenharia do…”
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Dissertation