Search Results - "Lopes, N. M. M."

70-gene signature as an aid for treatment decisions in early breast cancer: updated results of the phase 3 randomised MINDACT trial with an exploratory analysis by age by Piccart, Martine, van 't Veer, Laura J, Poncet, Coralie, Lopes Cardozo, Josephine M N, Delaloge, Suzette, Pierga, Jean-Yves, Vuylsteke, Peter, Brain, Etienne, Vrijaldenhoven, Suzan, Neijenhuis, Peter A, Causeret, Sylvian, Smilde, Tineke J, Viale, Giuseppe, Glas, Annuska M, Delorenzi, Mauro, Sotiriou, Christos, Rubio, Isabel T, Kümmel, Sherko, Zoppoli, Gabriele, Thompson, Alastair M, Matos, Erika, Zaman, Khalil, Hilbers, Florentine, Fumagalli, Debora, Ravdin, Peter, Knox, Susan, Tryfonidis, Konstantinos, Peric, Aleksandra, Meulemans, Bart, Bogaerts, Jan, Cardoso, Fatima, Rutgers, Emiel J T

“…The MINDACT trial showed excellent 5-year distant metastasis-free survival of 94·7% (95% CI 92·5–96·2) in patients with breast cancer of high clinical and low…”
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Combining method of detection and 70-gene signature for enhanced prognostication of breast cancer by Lopes Cardozo, J. M. N., Schmidt, M. K., van ’t Veer, L. J., Cardoso, F., Poncet, C., Rutgers, E. J. T., Drukker, C. A.

“…Purpose Studies have shown that screen detection by national screening programs is independently associated with better prognosis of breast cancer. The aim of…”
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Use of rhBMP-2 to reconstruct a severely atrophic mandible: a modified approach by Lopes, N.M.A, Vajgel, A, de Oliveira, D.M, de Santana Santos, T, Wassall, T

“…Abstract This study reports the case of a patient with a severely resorbed mandible who was treated without a bone graft, using short implants, internal rigid…”
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Effect of the inoculation of sugarcane silage with Lactobacillus hilgardii and Lactobacillus buchneri on feeding behavior and milk yield of dairy cows by Santos, W P, Ávila, C L S, Pereira, M N, Schwan, R F, Lopes, N M, Pinto, J C

“…Despite its low NDF digestibility, sugarcane is an option for feeding dairy cattle in tropical regions. We evaluated the effect of sugarcane silages inoculated…”
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Corn silage from corn treated with foliar fungicide and performance of Holstein cows by Haerr, K J, Lopes, N M, Pereira, M N, Fellows, G M, Cardoso, F C

“…Foliar fungicide application to corn plants is used in corn aimed for corn silage in the dairy industry, but questions regarding frequency of application and…”
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Outcome of Patients With an Ultralow-Risk 70-Gene Signature in the MINDACT Trial by Lopes Cardozo, Josephine M N, Drukker, Caroline A, Rutgers, Emiel J T, Schmidt, Marjanka K, Glas, Annuska M, Witteveen, Anke, Cardoso, Fatima, Piccart, Martine, Esserman, Laura J, Poncet, Coralie, van 't Veer, Laura J

“…Patients with 70-gene signature ultralow-risk breast cancers have shown excellent survival in historic cohorts, including randomized trials. The ultralow-risk…”
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Cell kill kinetics and cell cycle effects of taxol on human and hamster ovarian cell lines by LOPES, N. M, ADAMS, E. G, PITTS, T. W, BHUYAN, B. K

“…Taxol is a clinically active anticancer drug, which exerts its cytotoxicity by the unique mechanism of polymerizing tubulin monomers into microtubules and…”
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Outcome without any adjuvant systemic treatment in stage I ER+/HER2− breast cancer patients included in the MINDACT trial by Lopes Cardozo, J.M.N., Byng, D., Drukker, C.A., Schmidt, M.K., Binuya, M.A., van ’t Veer, L.J., Cardoso, F., Piccart, M., Smorenburg, C.H., Poncet, C., Rutgers, E.J.T.

“…Adjuvant systemic treatments (AST) reduce mortality, but have associated short- and long-term toxicities. Careful selection of patients likely to benefit from…”
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Agreement on risk assessment and chemotherapy recommendations among breast cancer specialists: A survey within the MINDACT cohort by Lopes Cardozo, Josephine M.N., Veira, Sherylene E., Ait Hassou, Laila, Uwimana, Aimé Lambert, Božović-Spasojević, Ivana, Bogaerts, Jan, Cardoso, Fatima, Schmidt, Marjanka K., Rutgers, Emiel J.T., Poncet, Coralie, Drukker, Caroline A.

“…Tailored recommendation for adjuvant chemotherapy in breast cancer patients is of great importance. This survey assessed agreement among oncologists on risk…”
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Iridoid and seco-iridoid glucosides from Chioccoca alba (Rubiaceae) by Carbonezi, Carlos Alberto, Martins, Dirceu, Young, Maria Claudia M, Lopes, Marcia N, Furlan, Maysa, Rodrigues Filho, Edson, Bolzani, Vanderlan da S

“…Phytochemical investigation of Chioccoca alba afforded three new iridoids, alboside I, alboside II and alboside III, and a new seco-iridoid alboside V…”
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GAMIFICATION AS A NEW TREND IN THE CO-CREATION PROCESS by Rodrigues, Ivo M F M, Soares, Nuno F M, Lopes, João M, Oliveira, José C, Lopes, Jorge M N G

“…Purpose: Interaction through the use of social media, smartphones, and online games is increasingly growing. Regarding games, it is estimated that part of the…”
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Triterpenes and Saponins from Rudgea viburnioides by Young, M. Claudia M, Araújo, Angela R, da Silva, Cristhiane A, Lopes, Marcia N, Trevisan, Ligia M. V, Bolzani, Vanderlan da S

“…A novel triterpene, viburgenin (1), has been isolated from an extract of the ripe fruit rinds of Rudgea viburnioides, together with the known saponins,…”
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Assessment of microtubule stabilizers by semiautomated in vitro microtubule protein polymerization and mitotic block assays by LOPES, N. M, MILLER, H. P, YOUNG, N. D, BHUYAN, B. K

“…Paclitaxel (Taxol) a clinically active anticancer agent, exerts its cytotoxicity by inducing tubulin polymerization, leading to cellular mitotic block. In…”
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12,13-Isotaxanes:  Synthesis of New Potent Analogs and X-ray Crystallographic Confirmation of Structure by Johnson, Roy A, Dobrowolski, Paul J, Nidy, Eldon G, Gebhard, Ilse, Qualls, Samuel J, Wicnienski, Nancy A, Kelly, Robert C, Pitts, Thomas W, Lopes, Narima M, DeKoning, Thomas F, Mattern, Sally J, Weed, Sheldon D, McGovren, J. Patrick, Chidester, Constance G

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Protein metabolism in the tumour-bearing mouse. Rates of protein synthesis in host tissues and in an Ehrlich ascites tumour at different stages in tumour growth by Lopes, M N, Black, P, Ashford, A J, Pain, V M

“…We have investigated the time course of the changes in protein metabolism in skeletal muscle and liver in mice during the progression of growth of an Ehrlich…”
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Abstract PS11-01: Outcome without adjuvant systemic treatment in breast cancer patients included in the MINDACT trial by Cardozo, Josephine MN Lopes, Byng, Danalyn, Drukker, Caroline A, Schmidt, Marjanka K, van 't Veer, Laura J, Cardoso, Fatima, Piccart, Martine, Poncet, Coralie, Rutgers, Emiel JTh

“…Abstract Background: Adjuvant systemic treatments have played an important role in the decline of breast cancer mortality over the years. Because of the…”
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Effect of glucoamylase, particle size, and duration of silage storage on dry matter loss and digestibility of ground corn rehydrated and ensiled by Lopes, N M, Cardoso, P C, Pereira, M N

“…Storing mature corn grain by rehydration and ensiling can improve digestibility by prolamin degradation in the silo. Particle size (PS) can determine the rate…”
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1388 Effect of glucoamylase, particle size, and duration of silage storage on dry matter loss and digestibility of ground corn rehydrated and ensiled by Lopes, N. M., Cardoso, P. C., Pereira, M. N.

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P6295Methotrexate reduces cardiac remodeling and improves left ventricle function in rats with Takotsubo cardiomyopathy by Guido, M C, Lopes, N M, Tavares, E R, Bispo, D L, Tavares De Melo, M D, Salemi, V M C, Maranhao, R C

“…Abstract Introduction Takotsubo cardiomyopathy (TC) is characterized by cardiac disfunction and left ventricle (LV) remodeling caused, mainly, by physical or…”
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P2577Losartan diminishes the expression of TGF-beta and improves cardiomyopathy in mice with Marfan syndrome by Guido, M C, Debbas, V, Lopes, N M, Ferreira-Filho, J C A, Salemi, V M C, Pereira, L V, Maranhao, R C, Laurindo, F R M

“…Abstract Introduction Marfan syndrome (MFS) is caused by mutations in the fibrillin-1 gene, leading to abnormal signaling of the transforming growth factor…”
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