Spatial-temporal pattern of colorectal cancer mortality in a Northeastern Brazilian State

Colorectal cancer (CRC) is one of the most common cancer types worldwide. Its increasing mortality trends, especially in emerging countries, are a concern. The aim of this study was to analyse mortality trends and spatial patterns of CRC in the state of Sergipe, Brazil, from 1990 to 2019. Trends wer...

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Bibliographic Details
Published in:	PloS one Vol. 19; no. 2; p. e0298100
Main Authors:	Moura, Alex R, Lopes, Mayara E G, Dantas, Mylena S, Marques, Adriane D, Britto, Érika de A C, Lima, Marcela S, Siqueira, Hianga F F, Lisboa, Ana C R, Moreira, Fernanda V S, Lima, Carlos A
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 23-02-2024 Public Library of Science (PLoS)
Subjects:	Analysis Brazil Care and treatment Colorectal cancer Developing countries Diagnosis Evaluation Mortality Patient outcomes Brazil
Online Access:	Get full text
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Summary:	Colorectal cancer (CRC) is one of the most common cancer types worldwide. Its increasing mortality trends, especially in emerging countries, are a concern. The aim of this study was to analyse mortality trends and spatial patterns of CRC in the state of Sergipe, Brazil, from 1990 to 2019. Trends were calculated using data from the Online Mortality Atlas and Joinpoint Regression Program 4.8.0.1. Spatial analyses were performed using the empirical Bayesian model and Moran indices calculated by TerraView 4.2.2 between 1990 to 1999, 2000 to 2009 and 2010 to 2019. A total of 1585 deaths were recorded during the study period, with 58.42% among females. Trends were increasing and constant for both sexes and all age groups studied. The highest mean annual percent change was 6.2 {95% Confidence interval (CI) 3.4;9.0} for males aged +65 years and 4.5 (95% CI 3.2;5.8) for females aged 50-64 years. There was positive spatial autocorrelation for both sexes in all periods studied when using the Moran index for Bayesian rates. In summary, a consistent trend of increasing colorectal cancer (CRC) mortality has been observed overall. Nevertheless, an altered spatial distribution among males has emerged over the studied period.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1932-6203 1932-6203
DOI:	10.1371/journal.pone.0298100