Search Results - "Lopes, Manuel"

The mTOR signalling pathway in human cancer by Pópulo, Helena, Lopes, José Manuel, Soares, Paula

“…The conserved serine/threonine kinase mTOR (the mammalian target of rapamycin), a downstream effector of the PI3K/AKT pathway, forms two distinct multiprotein…”
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Information-seeking, curiosity, and attention: computational and neural mechanisms by Gottlieb, Jacqueline, Oudeyer, Pierre-Yves, Lopes, Manuel, Baranes, Adrien

“…Highlights • Information-seeking can be driven by extrinsic or intrinsic rewards. • Curiosity may result from an intrinsic desire to reduce uncertainty. •…”
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Fish and mussels: importance of fish for freshwater mussel conservation by Modesto, Vanessa, Ilarri, Martina, Souza, Allan T., Lopes-Lima, Manuel, Douda, Karel, Clavero, Miguel, Sousa, Ronaldo Gomes

“…Co-extinctions are increasingly recognized as one of the major processes leading to the global biodiversity crisis, but there is still limited scientific…”
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A container loading algorithm with static mechanical equilibrium stability constraints by Galrão Ramos, A., Oliveira, José F., Gonçalves, José F., Lopes, Manuel P.

“…•Incorporation of static mechanical equilibrium conditions in the CLP.•New procedure for filling maximal-spaces, with evaluation of static stability.•Full…”
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Speeding up the detection of invasive bivalve species using environmental DNA: A Nanopore and Illumina sequencing comparison by Egeter, Bastian, Veríssimo, Joana, Lopes‐Lima, Manuel, Chaves, Cátia, Pinto, Joana, Riccardi, Nicoletta, Beja, Pedro, Fonseca, Nuno A.

“…Traditional detection of aquatic invasive species via morphological identification is often time‐consuming and can require a high level of taxonomic expertise,…”
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Pharmacogenomic biomarkers as source of evidence of the effectiveness and safety of antidepressant therapy by Correia, Catarina, Alcobia, Luciano, Lopes, Manuel José, Advinha, Ana Margarida

“…Objective The main goal of this work was to identify, describe, characterize, and classify the scientific evidence regarding the use of pharmacogenomic…”
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Pain as the fifth vital sign-A comparison between public and private healthcare systems by Pozza, Daniel Humberto, Azevedo, Luís Filipe, Castro Lopes, José Manuel

“…The assessment of pain as the fifth vital sign (P5VS) is of paramount importance since it leads to the management of undertreated pain, consequently reducing…”
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Intrinsically motivated oculomotor exploration guided by uncertainty reduction and conditioned reinforcement in non-human primates by Daddaoua, Nabil, Lopes, Manuel, Gottlieb, Jacqueline

“…Intelligent animals have a high degree of curiosity – the intrinsic desire to know – but the mechanisms of curiosity are poorly understood. A key open question…”
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Anomaly Analysis of PVC Roofing Membranes in Portugal by Lopes, Jorge Manuel Grandão

“…AbstractGiven that PVC membranes are a current solution for waterproofing flat roofs, and their use has been increasing in Portugal, it is important to analyze…”
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Freshwater mussel conservation: A global horizon scan of emerging threats and opportunities by Aldridge, David C., Ollard, Isobel S., Bespalaya, Yulia V., Bolotov, Ivan N., Douda, Karel, Geist, Juergen, Haag, Wendell R., Klunzinger, Michael W., Lopes‐Lima, Manuel, Mlambo, Musa C., Riccardi, Nicoletta, Sousa, Ronaldo, Strayer, David L., Torres, Santiago H., Vaughn, Caryn C., Zając, Tadeusz, Zieritz, Alexandra

“…We identified 14 emerging and poorly understood threats and opportunities for addressing the global conservation of freshwater mussels over the next decade. A…”
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Studies on the density, heat capacity, surface tension and infinite dilution diffusion with the ionic liquids [C 4mim][NTf 2], [C 4mim][dca], [C 2mim][EtOSO 3] and [ Aliquat][dca] by Nieto de Castro, Carlos A., Langa, Elisa, Morais, Ana L., Lopes, Manuel L. Matos, Lourenço, Maria J.V., Santos, Fernando J.V., Santos, M. Soledade C.S., Lopes, José N. Canongia, Veiga, Helena I.M., Macatrão, Mafalda, Esperança, José M.S.S., Marques, Carolina S., Rebelo, Luís P.N., Afonso, Carlos A.M.

“…Ionic liquids are a class of fluids that requires the attentions of experimentalist and theoreticians. In a new project on synthesis and characterization of…”
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Bacteriophages for Chronic Wound Treatment: from Traditional to Novel Delivery Systems by Pinto, Ana M, Cerqueira, Miguel A, Bañobre-Lópes, Manuel, Pastrana, Lorenzo M, Sillankorva, Sanna

“…The treatment and management of chronic wounds presents a massive financial burden for global health care systems, with significant and disturbing consequences…”
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The role of connectivity in conservation planning for species with obligatory interactions: Prospects for future climate scenarios by Silva, Janine P., Hermoso, Virgilio, Lopes‐Lima, Manuel, Miranda, Rafael, Filipe, Ana Filipa, Sousa, Ronaldo

“…Climate change may lead to range shifts, and barriers to such displacements may result in extirpations from previously suitable habitats. This may be…”
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A Nursing Care Intervention Model for Elderly People to Ascertain General Profiles of Functionality and Self Care Needs by Goes, Margarida, Lopes, Manuel José, Oliveira, Henrique, Fonseca, César, Marôco, João

“…A core set of International Classification of Functioning, Disability and Health codes was used to ascertain general profiles of functionality as a function of…”
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Portuguese nurses’ stress, anxiety, and depression reduction strategies during the COVID-19 outbreak by Guedes de Pinho, Lara Manuela, Sampaio, Francisco, Cruz Sequeira, Carlos Alberto, da Costa Teixeira, Laetitia, VICENTE DA FONSECA, CÉSAR JOÃO, Lopes, Manuel

“…The COVID-19 pandemic has contributed to mental health problems worldwide. Nurses are particularly prone to stress because they directly care for individuals…”
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Depression in older adults during the COVID‐19 pandemic: A systematic review by Silva, Celso, Fonseca, César, Ferreira, Rogério, Weidner, Anna, Morgado, Bruno, Lopes, Manuel J., Moritz, Steffen, Jelinek, Lena, Schneider, Brooke C., Pinho, Lara G.

“…Background Depression affected 5.7% of people aged 60 years and over prior to the pandemic and has increased by approximately 28%. The aim of this study is to…”
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Die‐offs of the endangered pearl mussel Margaritifera margaritifera during an extreme drought by Sousa, Ronaldo, Ferreira, André, Carvalho, Francisco, Lopes‐Lima, Manuel, Varandas, Simone, Teixeira, Amílcar

“…Droughts may be responsible for important ecological impacts in freshwater ecosystems, including the death of rare species. This study assessed the mortality…”
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Assessment of a terrestrial protected area for the conservation of freshwater biodiversity by Nogueira, Joana Garrido, Teixeira, Amílcar, Varandas, Simone, Lopes‐Lima, Manuel, Sousa, Ronaldo

“…Freshwater ecosystems are essential to human well‐being and most have high biodiversity. However, this biodiversity has been suffering severe declines owing to…”
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Psychometric properties of the WHOQOL-BREF(PT) in a sample of elderly citizens by Goes, Margarida, Lopes, Manuel, Marôco, João, Oliveira, Henrique, Fonseca, César

“…The goal of this article was to research the psychometric properties of the WHOQOL-BREF(PT) instrument in a sample of elderly citizens residing in a rural area…”
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Systematics, distribution, biology, and conservation of freshwater mussels (Bivalvia: Unionida) in China by Liu, Xiongjun, Liu, Yueying, Wu, Ruiwen, Zanatta, David T., Lopes‐Lima, Manuel, Gonçalves, Duarte V., Bogan, Arthur E., Ouyang, Shan, Wu, Xiaoping

“…Freshwater mussels (Mollusca: Bivalvia: Unionida) have a broad global distribution on every continent except Antarctica. However, owing to human activities,…”
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