Search Results - "Lopes, Julio César Dias"

Synthesis of Novel 1,2,3-Triazole Derivatives of Isocoumarins and 3,4-Dihydroisocoumarin with Potential Antiplasmodial Activity In Vitro by da Silva Santos, Lucas, de Carvalho, Matheus Fillipe Langanke, de Souza Pinto, Ana Claudia, da Fonseca, Amanda Luisa, Dias Lopes, Julio César, de Pilla Varotti, Fernando, de Freitas, Rossimiriam Pereira, Alves, Rosemeire Brondi

“…Malaria greatly affects the world health, having caused more than 228 million cases only in 2018. The emergence of drug resistance is one of the main problems…”
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Combined In Vitro Studies and in Silico Target Fishing for the Evaluation of the Biological Activities of Diphylleia cymosa and Podophyllum hexandrum by Rocha, Marina Pereira, Campana, Priscilla Rodrigues Valadares, Scoaris, Denise de Oliveira, Almeida, Vera Lucia de, Lopes, Julio Cesar Dias, Shaw, Julian Mark Hugh, Silva, Claudia Gontijo

“…This paper reports the in silico prediction of biological activities of lignans from and combined with an in vitro bioassays. The extracts from the leaves,…”
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Aspidosperma species: A review of their chemistry and biological activities by de Almeida, Vera Lúcia, Silva, Cláudia Gontijo, Silva, Andréia Fonseca, Campana, Priscilla Rodrigues Valadares, Foubert, Kenn, Lopes, Júlio César Dias, Pieters, Luc

“…Species of Aspidosperma are known popularly as “peroba, guatambu, carapanaúba, pau-pereiro” and “quina”. The genus can be found in the Americas, mainly between…”
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In vitro antileishmanial activity of leaf and stem extracts of seven Brazilian plant species by de Paula, Renata Cristina, da Silva, Sydnei Magno, Faria, Karen Ferraz, Frézard, Frédéric, Moreira, Carolina Paula de Souza, Foubert, Kenn, Lopes, Júlio César Dias, Campana, Priscilla Rodrigues Valadares, Rocha, Marina Pereira, Silva, Andréia Fonseca, Silva, Cláudia Gontijo, Pieters, Luc, Almeida, Vera Lúcia

“…Leishmaniasis is a parasitic disease that affects people all over the world. The number of cases of leishmaniasis is increasing and the drugs used for its…”
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Biological activities of extracts from Aspidosperma subincanum Mart. and in silico prediction for inhibition of acetylcholinesterase by Pereira Rocha, Marina, Rodrigues Valadares Campana, Priscilla, Oliveira Scoaris, Denise, Almeida, Vera Lúcia, Dias Lopes, Júlio César, Fonseca Silva, Andréia, Pieters, Luc, Gontijo Silva, Cláudia

“…Species of Aspidosperma are traditionally used to treat malaria, leishmaniasis, microbial, and inflammatory diseases. Aspidosperma subincanum Mart. known as…”
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Reply to the comment made by Šicho, Vorśilák and Svozil on ‘The Power metric: a new statistically robust enrichment-type metric for virtual screening applications with early recovery capability’ by De Winter, Hans, Lopes, Julio Cesar Dias

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The power metric: a new statistically robust enrichment-type metric for virtual screening applications with early recovery capability by Lopes, Julio Cesar Dias, dos Santos, Fábio Mendes, Martins-José, Andrelly, Augustyns, Koen, De Winter, Hans

“…A new metric for the evaluation of model performance in the field of virtual screening and quantitative structure–activity relationship applications is…”
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In silico pharmacological prediction and cytotoxicity of flavonoids glycosides identified by UPLC-DAD-ESI-MS/MS in extracts of Humulus lupulus leaves cultivated in Brazil by da Silva, Regislainy Gomes, Almeida, Tamires Cunha, Reis, Adriana Cotta Cardoso, Filho, Sidney Augusto Vieira, Brandão, Geraldo Célio, da Silva, Glenda Nicioli, de Sousa, Hildeberto Caldas, de Almeida, Vera Lúcia, Lopes, Julio César Dias, de Souza, Gustavo Henrique Bianco

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In silico pharmacological prediction and cytotoxicity of flavonoids glycosides identified by UPLC-DAD-ESI-MS/MS in extracts of Humulus lupulus leaves cultivated in Brazil by da Silva, Regislainy Gomes, Almeida, Tamires Cunha, Reis, Adriana Cotta Cardoso, Filho, Sidney Augusto Vieira, Brandão, Geraldo Célio, da Silva, Glenda Nicioli, de Sousa, Hildeberto Caldas, de Almeida, Vera Lúcia, Lopes, Julio César Dias, de Souza, Gustavo Henrique Bianco

“…Ethanolic (EB) extract and hexanic (SH) and hydromethanolic (SEM) sub-extracts of leaves were submitted to cytotoxicity evaluation and to phytochemical…”
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Investigação eletroquímica e calorimétrica da interação de novos agentes antitumorais biscatiônicos com DNA by Silva, Láuris Lucia da, Donnici, Claudio Luis, Lopes, Júlio César Dias, Goulart, Marília Oliveira Fonseca, Abreu, Fabiane Caxico de, Paula, Francine Santos de, Bravo, Carlos E. Salas, Santoro, Marcelo Matos, Denadai, Ângelo Márcio Leite, Santos, Alexandre Martins Costa, Montanari, Carlos Alberto

“…Biscationic amidines bind in the DNA minor groove and present biological activity against a range of infectious diseases. Two new biscationic compounds…”
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Conformational analysis and electronic interactions of 2-thiosubstituted cyclohexanones by semiempirical method PM3 by Faria, Luciano Emerich, Donnici, Claudio Luis, Lopes, Júlio César Dias

“…Some 2‐phenylthio‐para–substituted cyclohexanones with different oxidation states of sulfur atom were studied by systematic conformational search around C–S…”
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In silico pharmacological prediction and cytotoxicity of flavonoids glycosides identified by UPLC-DAD-ESI-MS/MS in extracts of Humulus lupulus leaves cultivated in Brazil by da Silva, Regislainy Gomes, Almeida, Tamires Cunha, Reis, Adriana Cotta Cardoso, Filho, Sidney Augusto Vieira, Brandão, Geraldo Célio, da Silva, Glenda Nicioli, de Sousa, Hildeberto Caldas, de Almeida, Vera Lúcia, Lopes, Julio César Dias, de Souza, Gustavo Henrique Bianco

“…Ethanolic (EB) extract and hexanic (SH) and hydromethanolic (SEM) sub-extracts of Humulus lupulus leaves were submitted to cytotoxicity evaluation and to…”
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Estudos de relações estrutura-atividade quantitativas (QSAR) de bis-benzamidinas com atividade antifúngica Quantitative structure-activity relationships (QSAR) studies of bisbenzamidines with antifungal activity by Vera L. de Almeida, Júlio César Dias Lopes, Sheila Rodrigues Oliveira, Claudio L. Donnici, Carlos A. Montanari

“…This paper describes 2D-QSAR and 3D-QSAR studies against Candida albicans and Cryptococcus neofarmans for a set of 20 bisbenzamidines. In the studies of…”
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Estudos de relações estrutura-atividade quantitativas (QSAR) de bis-benzamidinas com atividade antifúngica by Almeida, Vera L. de, Lopes, Júlio César Dias, Oliveira, Sheila Rodrigues, Donnici, Claudio L., Montanari, Carlos A.

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A QSAR Study on Pneumocystis carinii Topoisomerases of bis-Benzimidazoles by Rodrigues, Roberta de Faria, Lopes, Júlio César Dias, Montanari, Carlos A.

“…QSARs are presented for interactions between bis‐benzimidazoles and DNA denaturation temperatures and topo‐isomerases I and II of Pneumocystis carinii. A Carbo…”
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The Tropical Biominer Project: mining old sources for new drugs by Artiguenave, François, Lins, André, Maciel, Wesley Dias, Junior, Antonio Celso Caldeira, Nacif-Coelho, Carla, de Souza Linhares, Maria Margarida Ribeiro, de Oliveira, Guilherme Correa, Barbosa, Luis Humberto Rezende, Lopes, Júlio César Dias, Junior, Claudionor Nunes Coelho

“…The Tropical Biominer Project is a recent initiative from the Federal University of Minas Gerais (UFMG) and the Oswaldo Cruz foundation, with the participation…”
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