Search Results - "Lopes, Jaime L."

Uniparental disomy of multiple chromosomes in two cases with a complex phenotype by Polonis, Katarzyna, Lopes, Jaime L., Cabral, Huong, Babcock, Holly E., Kline, Laura, Ruiz, Kaylee M., Schwartz, Stuart, Hasadsri, Linda, Rowsey, Ross A., Hoppman, Nicole L.

“…Uniparental disomy (UPD) is the inheritance of both chromosomal homologs from one parent. Depending on the chromosome involved and the parental origin, UPD may…”
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The Innate Immune System Surveillance Biomarker p87 in African Americans and Caucasians with Small High-Grade Dysplastic Adenoma [SHiGDA] and Right-Sided JAK3 Colon Mutations May Explain the Presence of Multiple Cancers Revealing an Important Minority of Patients with JAK3 Mutations and Colorectal Neoplasia by Martin, Tobi, Zhao, Xiaoqing, Rodriquez, Rebecca, Tobi, Yosef Y, Ganguly, Tapan, Kuhn, Donald, McVicker, Benita, Lawson, Michael J, LiebII, John, Lopes, Jaime L

“…Colorectal cancer (CRC) outcomes in terms of incidence and mortality are significantly worse in African Americans than other Americans. While differences in…”
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Unconventional Diagnosis Based on Somatic Findings through Germ Line Whole-Exome Sequencing by Lopes, Jaime L, Rasmussen, Kristen J, Mehta, Nikita, Boczek, Nicole J, Hasadsri, Linda

“…Karyotyping for the bone marrow specimen was normal. [...]the patient's condition was ultimately diagnosed as clonal cytopenia of undetermined significance,…”
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Most noninvasive prenatal screens failing due to inadequate fetal cell free DNA are negative for trisomy when repeated by Lopes, Jaime L., Lopes, Guilherme S., Enninga, Elizabeth A. L., Kearney, Hutton M., Hoppman, Nicole L., Rowsey, Ross A.

“…Objective We aimed to test for an association between the amount of circulating fetal cell‐free DNA and trisomy, and whether NIPS failure due to low fetal…”
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Targeted Genotyping in Clinical Pharmacogenomics: What Is Missing? by Lopes, Jaime L, Harris, Kimberley, Karow, Mary Beth, Peterson, Sandra E, Kluge, Michelle L, Kotzer, Katrina E, Lopes, Guilherme S, Larson, Nicholas B, Bielinski, Suzette J, Scherer, Steven E, Wang, Liewei, Weinshilboum, Richard M, Black, 3rd, John L, Moyer, Ann M

“…Clinical pharmacogenomic testing typically uses targeted genotyping, which only detects variants included in the test design and may vary among laboratories…”
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FANCM, RAD1, CHEK1 and TP53I3 act as BRCA-like tumor suppressors and are mutated in hereditary ovarian cancer by Lopes, Jaime L., Chaudhry, Sophia, Lopes, Guilherme S., Levin, Nancy K., Tainsky, Michael A.

“…•Deficiency of CHEK1, FANCM and TP53I3 led to reduced homologous recombination repair efficiency.•Deficiency of RAD1, CHEK1 or FANCM led to a decrease in…”
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Identification of sex-specific genetic associations in response to opioid analgesics in a White, non-Hispanic cohort from Southeast Minnesota by Lopes, Guilherme S., Lopes, Jaime L., Bielinski, Suzette J., Armasu, Sebastian M., Zhu, Ye, Cavanaugh, Dana C., Moyer, Ann M., Jacobson, Debra J., Wang, Liwei, Jiang, Ruoxiang, St. Sauver, Jennifer L., Larson, Nicholas B.

“…The study of sex-specific genetic associations with opioid response may improve the understanding of inter-individual variability in pain treatments. We…”
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Characterizing false-positive fluorescence in situ hybridization results by mate-pair sequencing in a patient with chronic myeloid leukemia and progression to myeloid blast crisis by Lopes, Jaime L., Webley, Matthew, Pitel, Beth A., Pearce, Kathryn E., Smadbeck, James B., Johnson, Sarah H., Vasmatzis, George, Sukov, William R., Greipp, Patricia T., Hoppman, Nicole L., Ketterling, Rhett P., Baughn, Linda B., Finn, Laura, Peterson, Jess F.

“…•Newly acquired clonal chromosomal abnormalities in chronic myeloid leukemia (CML) usually indicate disease progression.•Conventional chromosome and…”
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35. Frequencies of Turner syndrome abnormalities as detected by high resolution chromosomal microarray in products of conception and postnatal blood samples by Lopes, Jaime L., Mitchell, Elyse, Ketterling, Rhett, Hoppman, Nicole

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16. Uniparental disomy (UPD) of multiple chromosomes in two cases with a complex phenotype by Polonis, Katarzyna, Lopes, Jaime L., Cabral, Huong, Hasadsri, Linda, Rowsey, Ross A., Hoppman, Nicole L.

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Most Non Invasive Prenatal Screens Failing Due to Inadequate Fetal Cell Free DNA are Negative for Trisomy when Repeated by Lopes, Jaime L., Lopes, Guilherme S., Enninga, Elizabeth Ann L., Kearney, Hutton M., Hoppman, Nicole L., Rowsey, Ross A.

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Targeted Genotyping in Clinical Pharmacogenomics by Lopes, Jaime L., Harris, Kimberley, Karow, Mary Beth, Peterson, Sandra E., Kluge, Michelle L., Kotzer, Katrina E., Lopes, Guilherme S., Larson, Nicholas B., Bielinski, Suzette J., Scherer, Steven E., Wang, Liewei, Weinshilboum, Richard M., Black, John L., Moyer, Ann M.

“…Clinical pharmacogenomic testing typically uses targeted genotyping, which only detects variants included in the test design and may vary among laboratories…”
Get full text

The Innate Immune System Surveillance Biomarker p87 in African Americans and Caucasians with Small High-Grade Dysplastic Adenoma SHiGDA and Right-Sided JAK3 Colon Mutations May Explain the Presence of Multiple Cancers Revealing an Important Minority of Patients with JAK3 Mutations and Colorectal Neoplasia by Tobi, Martin, Zhao, Xiaoqing, Rodriquez, Rebecca, Tobi, Yosef Y, Ganguly, Tapan, Kuhn, Donald, McVicker, Benita, Lawson, Michael J, Lieb, John, Lopes, Jaime L

“…Colorectal cancer (CRC) outcomes in terms of incidence and mortality are significantly worse in African Americans than other Americans. While differences in…”
Get full text