Search Results - "Lopes, Helena B."

Titanium With Nanotopography Induces Osteoblast Differentiation by Regulating Endogenous Bone Morphogenetic Protein Expression and Signaling Pathway by M.S. Castro-Raucci, Larissa, S. Francischini, Marcelo, N. Teixeira, Lucas, P. Ferraz, Emanuela, B. Lopes, Helena, T. de Oliveira, Paulo, Hassan, Mohammad Q., Rosa, Adalberto L., Beloti, Marcio M.

“…ABSTRACT We aimed at evaluating the effect of titanium (Ti) with nanotopography (Nano) on the endogenous expression of BMP‐2 and BMP‐4 and the relevance of…”
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Effect of Surface Nanotopography on Bone Response to Titanium Implant by Freitas, Gileade P, Lopes, Helena B, Martins-Neto, Evandro C, de Oliveira, Paulo T, Beloti, Marcio M, Rosa, Adalberto L

“…Clinical success of implant therapy is directly related to titanium (Ti) surface properties and the quality of bone tissue. The treatment of Ti implants with…”
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The Wnt/β-catenin signaling pathway is regulated by titanium with nanotopography to induce osteoblast differentiation by Abuna, Rodrigo P.F., Oliveira, Fabiola S., Lopes, Helena B., Freitas, Gileade P., Fernandes, Roger R., Rosa, Adalberto L., Beloti, Marcio M.

“…[Display omitted] •Fzd4 silencing by CRISPRi increased β-catenin phosphorylation and reduced Tcf expression.•Fzd4 silencing impaired osteoblast differentiation…”
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Mesenchymal stem cells overexpressing BMP-9 by CRISPR-Cas9 present high in vitro osteogenic potential and enhance in vivo bone formation by Freitas, Gileade P., Lopes, Helena B., Souza, Alann T. P., Gomes, Maria Paula O., Quiles, Georgia K., Gordon, Jonathan, Tye, Coralee, Stein, Janet L., Stein, Gary S., Lian, Jane B., Beloti, Marcio M., Rosa, Adalberto L.

“…Cell therapy is a valuable strategy for the replacement of bone grafts and repair bone defects, and mesenchymal stem cells (MSCs) are the most frequently used…”
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Participation of integrin β3 in osteoblast differentiation induced by titanium with nano or microtopography by Lopes, Helena B., Freitas, Gileade P., Elias, Carlos N., Tye, Coralee, Stein, Janet L., Stein, Gary S., Lian, Jane B., Rosa, Adalberto L., Beloti, Marcio M.

“…The major role of integrins is to mediate cell adhesion but some of them are involved in the osteoblasts–titanium (Ti) interactions. In this study, we…”
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Cell Therapy: Effect of Locally Injected Mesenchymal Stromal Cells Derived from Bone Marrow or Adipose Tissue on Bone Regeneration of Rat Calvarial Defects by Freitas, Gileade P., Lopes, Helena B., Souza, Alann T. P., Oliveira, Paula G. F. P., Almeida, Adriana L. G., Souza, Lucas E. B., Coelho, Paulo G., Beloti, Marcio M., Rosa, Adalberto L.

“…Treatment of large bone defects is a challenging clinical situation that may be benefited from cell therapies based on regenerative medicine. This study was…”
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Normoglycemia partially recovers the disrupted osteoblast differentiation of mesenchymal stem cells induced by type 1 but not type 2 diabetes mellitus by Weffort, Denise, Adolpho, Leticia F., Souza, Alann T. P., Freitas, Gileade P., Lopes, Helena B., Oliveira, Fabiola S., Bighetti‐Trevisan, Rayana L., Pitol‐Palin, Leticia, Matsushita, Doris H., Okamoto, Roberta, Beloti, Marcio M., Rosa, Adalberto L.

“…Type 1 (T1DM) and type 2 (T2DM) diabetes mellitus are characterized by changes in glucose metabolism and cause bone damage via a variety of mechanisms,…”
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Potential of Osteoblastic Cells Derived from Bone Marrow and Adipose Tissue Associated with a Polymer/Ceramic Composite to Repair Bone Tissue by Freitas, Gileade P., Lopes, Helena B., Almeida, Adriana L. G., Abuna, Rodrigo P. F., Gimenes, Rossano, Souza, Lucas E. B., Covas, Dimas T., Beloti, Marcio M., Rosa, Adalberto L.

“…One of the tissue engineering strategies to promote bone regeneration is the association of cells and biomaterials. In this context, the aim of this study was…”
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Selection of reference genes for quantitative real‐time polymerase chain reaction studies in rat osteoblasts by Abuna, Rodrigo P. F., Oliveira, Fabiola S., Ramos, Jaqueline I. R., Lopes, Helena B., Freitas, Gileade P., Souza, Alann T. P., Beloti, Marcio M., Rosa, Adalberto L.

“…Quantitative real‐time polymerase chain reaction (qRT‐PCR) is a powerful tool to evaluate gene expression, but its accuracy depends on the choice and stability…”
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MicroRNA 665 Regulates Dentinogenesis through MicroRNA-Mediated Silencing and Epigenetic Mechanisms by Heair, Hannah M., Kemper, Austin G., Roy, Bhaskar, Lopes, Helena B., Rashid, Harunur, Clarke, John C., Afreen, Lubana K., Ferraz, Emanuela P., Kim, Eddy, Javed, Amjad, Beloti, Marcio M., MacDougall, Mary, Hassan, Mohammad Q.

“…Studies of proteins involved in microRNA (miRNA) processing, maturation, and silencing have indicated the importance of miRNAs in skeletogenesis, but the…”
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Effect of cell therapy with osteoblasts differentiated from bone marrow or adipose tissue stromal cells on bone repair by Freitas, Gileade P, Lopes, Helena B, P Souza, Alann T, F P Oliveira, Paula G, G Almeida, Adriana L, Coelho, Paulo G, Ferreira, Fernanda U, Covas, Dimas T, Beloti, Marcio M, Rosa, Adalberto L

“…The aim of this study was to investigate the effect of local injection of osteoblasts differentiated from bone marrow (BM-OB) or adipose tissue (AT-OB)…”
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Participation of MicroRNA-34a and RANKL on bone repair induced by poly(vinylidene-trifluoroethylene)/barium titanate membrane by Lopes, Helena B., Ferraz, Emanuela P., Almeida, Adriana L. G., Florio, Pedro, Gimenes, Rossano, Rosa, Adalberto L., Beloti, Marcio M.

“…The poly(vinylidene-trifluoroethylene)/barium titanate (PVDF) membrane enhances in vitro osteoblast differentiation and in vivo bone repair. Here, we…”
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Participation of extracellular signal‐regulated kinases 1/2 in osteoblast and adipocyte differentiation of mesenchymal stem cells grown on titanium surfaces by Silva, Heitor F., Abuna, Rodrigo P. F., Lopes, Helena B., Francischini, Marcelo S., Oliveira, Paulo T., Rosa, Adalberto L., Beloti, Marcio M.

“…Osteoblasts and adipocytes coexist in the implantation site and affect the process of titanium (Ti) osseointegration. As extracellular signal‐regulated kinases…”
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Poly(vinylidene-trifluoroethylene)/barium titanate composite for in vivo support of bone formation by Lopes, Helena B, Santos, Thiago de S, de Oliveira, Fabiola S, Freitas, Gileade P, de Almeida, Adriana LG, Gimenes, Rossano, Rosa, Adalberto L, Beloti, Marcio M

“…In this study, we evaluated the effect of poly(vinylidene fluoride-trifluoroethylene)/barium titanate (P(VDF-TrFE)/BT) membrane on in vivo bone formation. Rat…”
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Positive effects of mesenchymal stem cells from healthy rats on the impaired osteoblast differentiation of mesenchymal stem cells from osteoporotic and diabetic rats by Souza, Alann T.P., Freitas, Gileade P., Lopes, Helena B., Weffort, Denise, Oliveira, Fabiola S., Beloti, Marcio M., Rosa, Adalberto L.

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Mesenchymal Stromal Cells Derived from Bone Marrow and Adipose Tissue: Isolation, Culture, Characterization and Differentiation by Freitas, Gileade P, Souza, Alann T P, Lopes, Helena B, Trevisan, Rayana L B, Oliveira, Fabiola S, Fernandes, Roger R, Ferreira, Fernanda U, Ros, Felipe A, Beloti, Marcio M, Rosa, Adalberto L

“…Since their discovery, mesenchymal stromal cells (MSCs) have received a lot of attention, mainly due to their self-renewal potential and multilineage…”
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The practice of telehealth by nurses: an experience in primary healthcare in Brazil by Sanches, Luiz M P, Alves, Danielle S, Lopes, Maria Helena B M, Novaes, Magdala A

“…In Brazil, in order to train the Family Health Strategy teams, the Health Ministry implemented the Brazil Telehealth Program to provide health support and…”
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