Search Results - "Lopes, Fernanda D.T.Q.S."
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Extracellular Matrix Component Remodeling in Respiratory Diseases: What Has Been Found in Clinical and Experimental Studies?
Published in Cells (Basel, Switzerland) (11-04-2019)“…Changes in extracellular matrix (ECM) components in the lungs are associated with the progression of respiratory diseases, such as asthma, chronic obstructive…”
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Structurally Related Monoterpenes p-Cymene, Carvacrol and Thymol Isolated from Essential Oil from Leaves of Lippia sidoides Cham. (Verbenaceae) Protect Mice against Elastase-Induced Emphysema
Published in Molecules (Basel, Switzerland) (20-10-2016)“…Chronic obstructive pulmonary disease (COPD) is characterized by irreversible airflow obstruction and inflammation. Natural products, such as monoterpenes,…”
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3
Correlation of fungi and endotoxin with PM2.5 and meteorological parameters in atmosphere of Sao Paulo, Brazil
Published in Atmospheric environment (1994) (01-04-2011)“…Particulate matter, especially PM2.5, is associated with increased morbidity and mortality from respiratory diseases. Studies that focus on the chemical…”
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Plant Proteinase Inhibitor BbCI Modulates Lung Inflammatory Responses and Mechanic and Remodeling Alterations Induced by Elastase in Mice
Published in BioMed research international (01-01-2017)“…Background. Proteinases play a key role in emphysema. Bauhinia bauhinioides cruzipain inhibitor (BbCI) is a serine-cysteine proteinase inhibitor. We evaluated…”
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Phenotypes of regulatory T cells in different stages of COPD
Published in International immunopharmacology (25-10-2024)“…•Despite the increase in resting Treg phenotypes during COPD development and progression, there is a failure in the Il-10 release by these cells, which precede…”
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Th17/Treg imbalance in COPD development: suppressors of cytokine signaling and signal transducers and activators of transcription proteins
Published in Scientific reports (17-09-2020)“…Th17/Treg imbalance contributes to chronic obstructive pulmonary disease (COPD) development and progression. However, intracellular signaling by suppressor of…”
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The Th17/Treg Cytokine Imbalance in Chronic Obstructive Pulmonary Disease Exacerbation in an Animal Model of Cigarette Smoke Exposure and Lipopolysaccharide Challenge Association
Published in Scientific reports (13-02-2019)“…We proposed an experimental model to verify the Th17/Treg cytokine imbalance in COPD exacerbation. Forty C57BL/6 mice were exposed to room air or cigarette…”
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The deleterious effects of smoking in bone mineralization and fibrillar matrix composition
Published in Life sciences (1973) (15-01-2020)“…This study aimed to verify the effects of cigarette smoke exposure in bone mineralization and fibrillar matrix composition as well as in bone healing after…”
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Aerobic exercise training engages cholinergic signaling to improve emphysema induced by cigarette smoke exposure in mice
Published in Life sciences (1973) (15-07-2022)“…Lung inflammation is modulated by cholinergic signaling and exercise training protects mice against pulmonary emphysema development; however, whether exercise…”
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Alpha-7 Nicotinic Receptor Agonist Protects Mice Against Pulmonary Emphysema Induced by Elastase
Published in Inflammation (01-06-2024)“…Pulmonary emphysema is a primary component of chronic obstructive pulmonary disease (COPD), a life-threatening disorder characterized by lung inflammation and…”
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Time-course effects of aerobic physical training in the prevention of cigarette smoke-induced COPD
Published in Journal of applied physiology (1985) (01-09-2017)“…A previous study by our group showed that regular exercise training (ET) attenuated pulmonary injury in an experimental model of chronic exposure to cigarette…”
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Long-term endogenous acetylcholine deficiency potentiates pulmonary inflammation in a murine model of elastase-induced emphysema
Published in Scientific reports (05-08-2021)“…Acetylcholine (ACh), the neurotransmitter of the cholinergic system, regulates inflammation in several diseases including pulmonary diseases. ACh is also…”
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Effects of the serine protease inhibitor rBmTI-A in an experimental mouse model of chronic allergic pulmonary inflammation
Published in Scientific reports (02-09-2019)“…To evaluate whether a recombinant serine protease inhibitor (rBmTI-A) modulates inflammation in an experimental model of chronic allergic lung inflammation…”
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Regulatory T-Cell Distribution within Lung Compartments in COPD
Published in Chronic obstructive pulmonary disease (03-09-2017)“…The importance of the adaptive immune response, specifically the role of regulatory T (Treg) cells in controlling the obstruction progression in smokers, has…”
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A flavanone from Baccharis retusa (Asteraceae) prevents elastase-induced emphysema in mice by regulating NF-κB, oxidative stress and metalloproteinases
Published in Respiratory research (30-06-2015)“…Pulmonary emphysema is characterized by irreversible airflow obstruction, inflammation, oxidative stress imbalance and lung remodeling, resulting in reduced…”
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Aerobic exercise attenuates pulmonary inflammation induced by Streptococcus pneumoniae
Published in Journal of applied physiology (1985) (01-11-2014)“…Aerobic exercise has been recognized as a stimulator of the immune system, but its effect on bacterial infection has not been extensively evaluated. We studied…”
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rBmTI-6 attenuates pathophysiological and inflammatory parameters of induced emphysema in mice
Published in International journal of biological macromolecules (01-05-2018)“…Protease/anti-protease imbalance is the main pathogenic mechanism of emphysema and protease inhibitors have been recognized as potential molecules to treat the…”
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Compensatory lung growth after bilobectomy in emphysematous rats
Published in PloS one (27-07-2017)“…Lung volume reduction surgery (LVRS) is an option for emphysematous patients who are awaiting lung transplantation. LVRS reduces nonfunctional portions of lung…”
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A treatment with a protease inhibitor recombinant from the cattle tick (Rhipicephalus Boophilus microplus) ameliorates emphysema in mice
Published in PloS one (02-06-2014)“…To determine whether a serine protease inhibitor treatment can prevent or minimize emphysema in mice. C57BL/6 mice were subjected to porcine pancreatic…”
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Th17/Treg-Related Intracellular Signaling in Patients with Chronic Obstructive Pulmonary Disease: Comparison between Local and Systemic Responses
Published in Cells (Basel, Switzerland) (22-06-2021)“…Th17/Treg imbalance plays a pivotal role in COPD development and progression. We aimed to assess Th17/Treg-related intracellular signaling at different COPD…”
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