Search Results - "Lopes, Débora de Oliveira"
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Characterization of Lectin from Bauhinia holophylla Using Bioinformatics Tools
Published in Horticulturae (01-07-2024)“…Lectins are proteins of a non-immune nature with activity against microorganisms, insects, and tumor cells. The aim of this work was to predict the…”
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Mutation screening of TP53, CHEK2 and BRCA genes in patients at high risk for hereditary breast and ovarian cancer (HBOC) in Brazil
Published in Breast cancer (Tokyo, Japan) (01-05-2019)“…Background Few studies related to hereditary breast and ovarian cancer syndrome (HBOC) have been conducted in Brazil, and they are restricted to only small…”
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Molecular surveillance of dengue in Minas Gerais provides insights on dengue virus 1 and 4 circulation in Brazil
Published in Journal of medical virology (01-06-2017)“…Dengue, caused by any of the four types of Dengue virus (DENV) is the most important arbovirus in the world. In this study we performed a molecular…”
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The Corynebacterium pseudotuberculosis genome contains two formamidopyrimidine-DNA glycosylase enzymes, only one of which recognizes and excises 8-oxoguanine lesion
Published in Gene (10-01-2016)“…The GO-system is a DNA repair mechanism that prevents and corrects oxidative DNA damage. Formamidopyrimidine-DNA glycosylase (FPG/MutM) participates in this…”
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Clinical, Molecular, and Epidemiological Analysis of Dengue Cases during a Major Outbreak in the Midwest Region of Minas Gerais, Brazil
Published in Journal of Tropical Medicine (01-01-2014)“…This study aims to perform the first molecular and clinical-epidemiological analysis of dengue cases in Divinopolis, MG, Brazil. Data from 4,110 cases of…”
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Reverse and structural vaccinology approach to design a highly immunogenic multi-epitope subunit vaccine against Streptococcus pneumoniae infection
Published in Infection, genetics and evolution (01-11-2020)“…Streptococcus pneumoniae is a pathogen that resides in the upper respiratory tract of healthy individuals, maintaining a commensal relationship with its host…”
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Occurrence of schistosomiasis in Divinópolis-MG based on study of schoolchildren and surveys of disease notification
Published in Jornal brasileiro de patologia e medicina laboratorial (01-08-2014)“…Introduction: Schistosomiasis is a neglected chronic disease that affects mainly underdeveloped regions, including Brazil. Objective: To evaluate the…”
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The role of IL-10 in immune responses against Pseudomonas aeruginosa during acute lung infection
Published in Cell and tissue research (01-03-2021)“…Pseudomonas aeruginosa is considered an opportunistic pathogen of great clinical importance. The clearance of this bacterium occurs through recognition of the…”
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Rational selection of immunodominant and preserved epitope Sm043300e from Schistosoma mansoni and design of a chimeric molecule for biotechnological purposes
Published in Molecular immunology (01-01-2018)“…•Use of computational tools in the development of vaccines against human diseases.•Rational development and structural verification of chimeric proteins.•The…”
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Assays with recombinant soluble isoforms of DC-SIGN, a dengue virus ligand, show variation in their ability to bind to mannose residues
Published in Archives of virology (01-11-2019)“…The DC-SIGN glycoprotein is responsible for the initial adhesion of dengue virus (DENV) to immune cells by the carbohydrate recognition domain (CRD). There are…”
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Adenine Glycosylase MutY of Corynebacterium pseudotuberculosis presents the antimutator phenotype and evidences of glycosylase/AP lyase activity in vitro
Published in Infection, genetics and evolution (01-10-2016)“…Corynebacterium pseudotuberculosis is the etiological agent of caseous lymphadenitis, a disease that predominantly affects small ruminants, causing significant…”
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12
Screening of the BRCA1 gene in Brazilian patients with breast and/or ovarian cancer via high-resolution melting reaction analysis
Published in Familial cancer (01-04-2016)“…The aim of this study was to evaluate the profile of BRCA1 mutations among cancer-affected Brazilian women from the Midwest region of Minas Gerais state with…”
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Identification of a vaccine against schistosomiasis using bioinformatics and molecular modeling tools
Published in Infection, genetics and evolution (01-12-2013)“…•Fourteen promiscuous epitopes were identified in Schistosoma mansoni data base by using bioinformatics.•Eleven peptides presented thermodynamically stable…”
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Cytotoxic Activities of Eosinophil Cationic Protein and Eosinophil-derived Neurotoxin: In Silico Analysis
Published in Cancer genomics & proteomics (01-11-2015)“…Eosinophil cationic protein (ECP) and eosinophil derived-neurotoxin (EDN) are homologous ribonuclease (RNAse) A family proteins. The objective of the present…”
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Chemical composition and evaluation of the anti-inflammatory and antinociceptive activities of Duguetia furfuracea essential oil: Effect on edema, leukocyte recruitment, tumor necrosis factor alpha production, iNOS expression, and adenosinergic and opioidergic systems
Published in Journal of ethnopharmacology (01-03-2019)“…Duguetia furfuracea (A. St. -Hil.) Saff. (Annonaceae) is commonly known in Brazil as “araticum-seco,” and its root is used in folk medicine to treat…”
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Foreshadowing an exponential market: A brief story, applications, and perspectives of CRISPR/Cas system for the production of (hemi-)cellulases in filamentous fungi
Published in Fungal biology reviews (01-09-2024)“…The demand to develop protein production systems that are both economically and scientifically viable is reflected in the global scenario, where filamentous…”
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Soluble isoforms of the DC-SIGN receptor can increase the dengue virus infection in immature dendritic cells
Published in The Brazilian journal of infectious diseases (01-11-2024)“…Dengue is a disease with a high-impact on public health worldwide. Many researches have focused on the cell receptors involved in its pathogenesis. The role of…”
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Cervical uterine lesions: An epidemiological and molecular investigation in midwestern Minas Gerais, Brazil
Published in Journal of medical virology (01-05-2013)“…Cervical uterine cancer is the second most frequent form of cancer in the female population and the fourth cause of cancer deaths among Brazilian women. In…”
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Anti-inflammatory and central and peripheral anti-nociceptive activities of α-asarone through the inhibition of TNF-α production, leukocyte recruitment and iNOS expression, and participation of the adenosinergic and opioidergic systems
Published in Inflammopharmacology (01-08-2020)“…Alpha-asarone has been found to possess many pharmacological activities, which can improve cognitive function and exert anti-oxidant, anxiolytic,…”
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The polyanions heparin and suramin impede binding of free adenine to a DNA glycosylase from C. pseudotuberculosis
Published in International journal of biological macromolecules (15-03-2019)“…Currently no effective treatment is available to combat infections caused by Corynebacterium pseudotuberculosis in livestock. Survival of this Gram-positive…”
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