Search Results - "Lopes, Carla"
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Overview on gastroretentive drug delivery systems for improving drug bioavailability
Published in International journal of pharmaceutics (20-08-2016)“…[Display omitted] In recent decades, many efforts have been made in order to improve drug bioavailability after oral administration. Gastroretentive drug…”
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Surface-modified lipid nanocarriers for crossing the blood-brain barrier (BBB): A current overview of active targeting in brain diseases
Published in Colloids and surfaces, B, Biointerfaces (01-01-2023)“…The blood-brain barrier (BBB) restricts the access of therapeutic agents to the brain, complicating the treatment of neurological diseases, such as Alzheimer’s…”
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Centriolar satellites are assembly points for proteins implicated in human ciliopathies, including oral-facial-digital syndrome 1
Published in Journal of cell science (15-02-2011)“…Ciliopathies are caused by mutations in genes encoding proteins required for cilia organization or function. We show through colocalization with PCM-1, that…”
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Centrosome amplification arises before neoplasia and increases upon p53 loss in tumorigenesis
Published in The Journal of cell biology (02-07-2018)“…Centrosome abnormalities are a typical hallmark of human cancers. However, the origin and dynamics of such abnormalities in human cancer are not known. In this…”
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Folate and folic acid in the periconceptional period: recommendations from official health organizations in thirty-six countries worldwide and WHO
Published in Public health nutrition (01-01-2016)“…To summarize the recommendations on folate intake and folic acid supplementation and fortification in the periconceptional period, aimed at prevention of…”
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Replication levels, false presences and the estimation of the presence/absence from eDNA metabarcoding data
Published in Molecular ecology resources (01-05-2015)“…Environmental DNA (eDNA) metabarcoding is increasingly used to study the present and past biodiversity. eDNA analyses often rely on amplification of very small…”
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PLK4 trans-Autoactivation Controls Centriole Biogenesis in Space
Published in Developmental cell (26-10-2015)“…Centrioles are essential for cilia and centrosome assembly. In centriole-containing cells, centrioles always form juxtaposed to pre-existing ones, motivating a…”
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Editorial on special issue “Lipid nanosystems for local drug delivery”
Published in Pharmaceutics (01-07-2023)“…Nanosystems provide an attractive approach to pharmacological therapy, with the possibility of enhancing the performance and overcoming the constraints of…”
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The oral-facial-digital syndrome gene C2CD3 encodes a positive regulator of centriole elongation
Published in Nature genetics (01-08-2014)“…Maxence Nachury, Christel Thauvin-Robinet and colleagues identify mutations in C2CD3 in two families with oral-facial-digital syndrome. They further show that…”
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Evaluation of a short food frequency questionnaire for dietary intake assessment among children
Published in European journal of clinical nutrition (01-05-2019)“…Background/objectives The objective of this study was to evaluate the performance of a short food frequency questionnaire (FFQ) to assess dietary intake at 4…”
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Lyotropic liquid crystalline 2D and 3D mesophases: Advanced materials for multifunctional anticancer nanosystems
Published in Biochimica et biophysica acta. Reviews on cancer (01-11-2023)“…Cancer remains a leading cause of mortality. Despite significant breakthroughs in conventional therapies, treatment is still far from ideal due to high…”
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Navigating Neurotoxicity and Safety Assessment of Nanocarriers for Brain Delivery: Strategies and Insights
Published in Acta biomaterialia (01-11-2024)“…Nanomedicine, an area that uses nanomaterials for theragnostic purposes, is advancing rapidly, particularly in the detection and treatment of neurodegenerative…”
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Eye selector logic for a coordinated cell cycle exit
Published in PLoS genetics (01-02-2015)“…Organ-selector transcription factors control simultaneously cell differentiation and proliferation, ensuring the development of functional organs and their…”
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Cadmium exposure and risk of breast cancer: A dose-response meta-analysis of cohort studies
Published in Environment international (01-09-2020)“…•We carried out a dose-response meta-analysis on Cd exposure and breast cancer.•We found a marginal and statistically imprecise relation with dietary Cd…”
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Studying Centriole Duplication and Elongation in Human Cells
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2020)“…Centrioles assemble centrosomes and cilia/flagella, which are microtubule-based structures with key roles in cell division, polarity, motility, and signaling…”
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Systematic review of saturated fatty acids on inflammation and circulating levels of adipokines
Published in Nutrition research (New York, N.Y.) (01-09-2013)“…Abstract Diet is one factor that plays a part in coronary heart disease risk through multiple biological mechanisms including subclinical inflammation. In this…”
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Steady-state and time-resolved fluorescence of chlorophyll extracted of sunflower seedlings primed with green synthesized silver and copper nanoparticles
Published in Applied physics. A, Materials science & processing (2024)“…Nanopriming is a pre-sowing treatment in which seeds are soaked in nanoparticle solutions for a determined period. This process enhances germination…”
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pH-responsive hybrid nanoassemblies for cancer treatment: formulation development, optimization, and In vitro therapeutic performance
Published in Pharmaceutics (2023)“…Current needs for increased drug delivery carrier efficacy and specificity in cancer necessitate the adoption of intelligent materials that respond to…”
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Co-Designing Research for Sustainable Food Systems and Diets with Aboriginal Communities: A Study Protocol
Published in International journal of environmental research and public health (04-03-2024)“…(1) Background: Food choices and systems have contributed to various health and environmental issues, resulting in the global syndemic (obesity, undernutrition…”
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Fatty Acids Consumption: The Role Metabolic Aspects Involved in Obesity and Its Associated Disorders
Published in Nutrients (22-10-2017)“…Obesity and its associated disorders, such as insulin resistance, dyslipidemia, metabolic inflammation, dysbiosis, and non-alcoholic hepatic steatosis, are…”
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