Search Results - "Lopes, Cátia D.F"

BDNF gene delivery mediated by neuron-targeted nanoparticles is neuroprotective in peripheral nerve injury by Lopes, Cátia D.F, Gonçalves, Nádia P, Gomes, Carla P, Saraiva, Maria J, Pêgo, Ana P

“…Abstract Neuron-targeted gene delivery is a promising strategy to treat peripheral neuropathies. Here we propose the use of polymeric nanoparticles based on…”
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Ibuprofen-loaded fibrous patches—taming inhibition at the spinal cord injury site by Pires, Liliana R., Lopes, Cátia D. F., Salvador, Daniela, Rocha, Daniela N., Pêgo, Ana Paula

“…It is now widely accepted that a therapeutic strategy for spinal cord injury (SCI) demands a multi-target approach. Here we propose the use of an easily…”
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A high-throughput bioimaging study to assess the impact of chitosan-based nanoparticle degradation on DNA delivery performance by Gomes, Carla P., Varela-Moreira, Aida, Leiro, Victoria, Lopes, Cátia D.F., Moreno, Pedro M.D., Gomez-Lazaro, Maria, Pêgo, Ana P.

“…[Display omitted] By using imaging flow cytometry as a powerful statistical high-throughput technique we investigated the impact of degradation on the…”
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Dendrimers as Powerful Building Blocks in Central Nervous System Disease: Headed for Successful Nanomedicine by Leiro, Victoria, Duque Santos, Sofia, Lopes, Cátia D. F., Paula Pêgo, Ana

“…Dendrimers have emerged as a powerful class of nanomaterials in the nanomedicine field due to their unique structural features: globular, well‐defined, highly…”
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Atomic Force Microscopy as a Tool to Assess the Specificity of Targeted Nanoparticles in Biological Models of High Complexity by Gomes, Carla P., Lopes, Cátia D. F., Leitner, Michael, Ebner, Andreas, Hinterdorfer, Peter, Pêgo, Ana P.

“…The ability to design nanoparticle delivery systems capable of selectively target their payloads to specific cell populations is still a major caveat in…”
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Interfacing Microfluidics with Microelectrode Arrays for Studying Neuronal Communication and Axonal Signal Propagation by Lopes, Cátia D.F., Mateus, José C., Aguiar, Paulo

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The membrane periodic skeleton is an actomyosin network that regulates axonal diameter and conduction by Costa, Ana Rita, Sousa, Sara C, Pinto-Costa, Rita, Mateus, José C, Lopes, Cátia Df, Costa, Ana Catarina, Rosa, David, Machado, Diana, Pajuelo, Luis, Wang, Xuewei, Zhou, Feng-Quan, Pereira, António J, Sampaio, Paula, Rubinstein, Boris Y, Mendes Pinto, Inês, Lampe, Marko, Aguiar, Paulo, Sousa, Monica M

“…Neurons have a membrane periodic skeleton (MPS) composed of actin rings interconnected by spectrin. Here, combining chemical and genetic gain- and…”
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µSpikeHunter: An advanced computational tool for the analysis of neuronal communication and action potential propagation in microfluidic platforms by Heiney, Kristine, Mateus, José C., Lopes, Cátia D. F., Neto, Estrela, Lamghari, Meriem, Aguiar, Paulo

“…Understanding neuronal communication is fundamental in neuroscience, but there are few methodologies offering detailed analysis for well-controlled conditions…”
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Interfacing Microfluidics with Microelectrode Arrays for Studying Neuronal Communication and Axonal Signal Propagation by Lopes, Cátia D F, Mateus, José C, Aguiar, Paulo

“…Microelectrode arrays (MEAs) are widely used to study neuronal function in vitro. These devices allow concurrent non-invasive recording/stimulation of…”
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Microfluidic-based platform to mimic the in vivo peripheral administration of neurotropic nanoparticles by Lopes, Cátia Df, Gomes, Carla P, Neto, Estrela, Sampaio, Paula, Aguiar, Paulo, Pêgo, Ana P

“…Propose a nanoparticle for neuron-targeted retrograde gene delivery and describe a microfluidic-based culture system to provide insight into vector performance…”
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In vivo targeted gene delivery to peripheral neurons mediated by neurotropic poly(ethylene imine)-based nanoparticles by Lopes, Cátia Df, Oliveira, Hugo, Estevão, Inês, Pires, Liliana Raquel, Pêgo, Ana Paula

“…A major challenge in neuronal gene therapy is to achieve safe, efficient, and minimally invasive transgene delivery to neurons. In this study, we report the…”
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Neuron–microglia contact-dependent mechanisms attenuate methamphetamine-induced microglia reactivity and enhance neuronal plasticity by Bravo, Joana, Ribeiro, Inês, Terceiro, Ana Filipa, Bonifácio Andrade, Elva, Portugal, Camila Cabral, Lopes, Igor M., Azevedo, Maria M., Sousa, Mafalda, Lopes, Cátia D. F., Lobo, Andrea C., Canedo, Teresa, Relvas, João Bettencourt, Summavielle, Teresa

“…Exposure to methamphetamine (Meth) has been classically associated with damage to neuronal terminals. However, it is now becoming clear that addiction may also…”
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